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Immunogenetics --- Immunoglobulins --- Immunogenetics. --- Immunoglobulins.
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Human Immunogenetics. --- Immunologic diseases --- Immunogenetics. --- Genetic aspects.
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This dissertation by Hammoudi Alkaissi explores the genetic factors involved in mercury-induced autoimmunity (HgIA) using genome-wide association studies (GWAS). The research identifies candidate genes associated with autoimmune phenotypes and mercury excretion in mice. Key findings suggest that genes such as Bank1 and Nfkb1 play crucial roles in the development of autoantibodies, while Pprc1 is implicated in mercury regulation in the kidneys. The study employs various genetic analysis techniques to map quantitative trait loci (QTL) associated with these conditions, aiming to improve the understanding of autoimmune disease mechanisms and mercury toxicity. The intended audience includes researchers and professionals in immunology and genetic pathology.
Immunogenetics. --- Autoimmune diseases. --- Immunogenetics --- Autoimmune diseases
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Immunogenetics --- Histocompatibility --- Primates
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