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Guidebook to the homeobox genes
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ISBN: 0198599404 Year: 1994 Publisher: Oxford Oxford University Press

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Sudden origins : fossils, genes, and the emergence of species
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ISBN: 0471329851 0471379123 Year: 1999 Publisher: New York, NY : John Wiley,

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The greatest riddle of evolution has been the following puzzle: while Darwin argued that new species emerge through a slow, gradual accumulation of tiny mutations, the fossil record reveals a very different scenario--the sudden emergence of whole new species, with no apparent immediate ancestors. This discrepancy has fueled heated debate among evolutionary theorists and has provided unfortunate fodder to creationists, who see it as proof that evolution doesn't happen at all.Now, in this provocative and timely book, leading paleoanthropologist Jeffrey Schwartz presents a groundbreaking and radical new theory of evolution, which brings together evidence from genetics, paleontology, embryology, and anatomy to solve this great outstanding riddle. Central to the new theory is the recent discovery of a special kind of gene, known as homeobox genes, which can cause dramatic mutations that express themselves suddenly in the form of a new species. Such a new species will appear to have arisen out of thin air, with no lineage of ancestors. The new theory preserves natural selection, but shows that it is not the primary engine driving evolution, after all.Writing with graceful prose and the expert knowledge only an insider can bring, Jeffrey Schwartz begins by taking readers on a fascinating journey through the whole history of evolutionary thinking and discovery, recounting the major events and disputes. He also introduces the intriguing puzzles encountered along the way in the study of human evolution and shows how, despite early alternative theories advanced by some of the greatest scientific minds of the nineteenth and twentieth centuries, gradualism became a matter of scientific orthodoxy. His account includes the stories behind such highlights as the infamous Piltdown hoax and the remarkable discovery of the astonishingly complete Lucy skeleton.Schwartz then introduces the series of important recent discoveries in developmental biology and genetics that paved the

HOX gene expression
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ISBN: 1281044512 9786611044510 0387689907 0387689893 1441923977 Year: 2007 Publisher: Austin,Tex : New York : Landes Bioscience/Eurekah.com ; Springer Science + Business Media,

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The study of Hox genes is crucial not only in exploring the enigma of homeosis but also in understanding normal development at the fundamental molecular level. "Hox Gene Expression" starts with the amazing discovery of the homeobox twenty-three years ago and follows the exciting path thereafter of a series of breakthroughs in Genetics, Development and Evolution. It deals with homeotic genes- their evolution, structure, normal and abnormal function. Researchers and graduate students in Biology and Medicine will benefit from this integrated overview of Hox gene activities.


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Hox genes : studies from the 20th to the 21st century
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ISBN: 1441966722 9786613074492 1441966730 1283074494 Year: 2010 Publisher: New York : Austin, Tex. : Springer Science+Business Media ; Landes Bioscience,

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In his 1894 book, Materials for the Study of Variation, William Bateson coined the term Homoeosis with the following prose: The case of the modification of the antenna of an insect into a foot, of the eye of a Crustacean into an antenna, of a petal into a stamen, and the like, are examples of the same kind. It is desirable and indeed necessary that such Variations, which consist in the assumption by one member of a Meristic series, of the form or characters proper to other members of the series, should be recognized as constituting a distinct group of phenomena. ...I therefore propose...the term HOMOEOSIS...; for the essential phenomenon is not that there has merely been a change, but that something has been changed into the likeness of something else. The book was intended as a listing of the kinds of naturally occurring variation that could act as a substrate for the evolutionary process and Bateson took his examples from collections, both private and in museums, of materials displaying morphological oddities. Interestingly the person who also coined the term “Genetics” proffered little in the way of speculation on the possible genetic underpinnings of these oddities. It wasn’t until the early part of the next century that these changes in meristic series were shown to be heritable.


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Matters of life and death : perspectives on public health, molecular biology, cancer, and the prospects for the human race
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ISBN: 0691002509 Year: 1997 Publisher: Princeton (N.J.): Princeton university press

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Cancer has become the scourge of the twentieth century. It was always part of the human condition, but until recently it was not a common cause of death because most people died from the infectious diseases. Now that so many of us will live long enough to develop cancer, we need to learn as much about it as we can. This requires some understanding of molecular biology. John Cairns has made significant contributions to cancer research, molecular biology, and virology. He believes that it is possible to explain what is known about cancer and about molecular biology in terms that are easily understood by people with little or no scientific training. In this fascinating book, he explores the revolution in public health, the origins and principles of molecular biology, and our emerging understanding of the causes of cancer. Finally, he discusses how these developments are likely to affect future generations. As Cairns points out, the last two hundred years have altered our life expectations beyond all recognition. Even in the less developed nations of the world, people are starting to believe that everyone ought to be able to live into old age and be protected from the major causes of premature death. This change in our expectations is one of the major benefits of technology and the biological sciences. But the resulting explosion in the human population ultimately threatens everything we have gained by scientific progress.

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