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Hematologic Neoplasms --- Hematology --- Hematological oncology --- Hématologie --- Hématocancérologie --- Periodicals. --- Periodicals --- Périodiques --- Hematologic Neoplasms. --- Hematology. --- Hematologic Malignancy --- Hematological Malignancies --- Hematological Neoplasms --- Hematopoietic Malignancies --- Malignancies, Hematologic --- Malignancy, Hematologic --- Neoplasms, Hematologic --- Neoplasms, Hematopoietic --- Hematologic Malignancies --- Hematopoietic Neoplasms --- Hematologic Neoplasm --- Hematological Malignancy --- Hematological Neoplasm --- Hematopoietic Malignancy --- Hematopoietic Neoplasm --- Malignancies, Hematological --- Malignancies, Hematopoietic --- Malignancy, Hematological --- Malignancy, Hematopoietic --- Neoplasm, Hematologic --- Neoplasm, Hematological --- Neoplasm, Hematopoietic --- Neoplasms, Hematological --- Haematology --- hematologic malignancies --- blood cancer --- immunology --- Internal medicine --- Blood --- Diseases --- Oncology. Neoplasms --- Blood Cancer --- Blood Cancers --- Cancer, Blood --- Hématologie

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Cancer Epidemiology and Prevention --- cancer genetics --- Cancer Imaging and Image-directed Interventions --- Cancer Immunity and Immunotherapy --- Molecular Targets and Therapeutics --- Gastrointestinal cancers --- Genitourinary oncology --- head and neck cancer --- Hematologic Malignancies Metabolism --- molecular and cellular oncology --- Neuro-Oncology and Neurosurgical Oncology --- pediatric oncology --- Pharmacology of Anti-Cancer Drugs --- Radiation Oncology --- surgical oncology --- thoracic oncology --- women's cancer

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Hematology --- Hematology. --- Hematologic Neoplasms. --- Haematology --- Internal medicine --- Blood --- Hematologic Malignancy --- Hematological Malignancies --- Hematological Neoplasms --- Hematopoietic Malignancies --- Malignancies, Hematologic --- Malignancy, Hematologic --- Neoplasms, Hematologic --- Neoplasms, Hematopoietic --- Hematologic Malignancies --- Hematopoietic Neoplasms --- Hematologic Neoplasm --- Hematological Malignancy --- Hematological Neoplasm --- Hematopoietic Malignancy --- Hematopoietic Neoplasm --- Malignancies, Hematological --- Malignancies, Hematopoietic --- Malignancy, Hematological --- Malignancy, Hematopoietic --- Neoplasm, Hematologic --- Neoplasm, Hematological --- Neoplasm, Hematopoietic --- Neoplasms, Hematological --- Cancer --- Diseases --- leukemia --- toxicity --- flow cytometry --- hematology --- Blood Cancer --- Blood Cancers --- Cancer, Blood

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Blood --- Hematology --- Hematologic Neoplasms. --- Hematology. --- Cancer. --- Health. --- Diseases --- Diseases. --- Clinical hematology --- Hematologic diseases --- Hematologic Malignancy --- Hematological Malignancies --- Hematological Neoplasms --- Hematopoietic Malignancies --- Malignancies, Hematologic --- Malignancy, Hematologic --- Neoplasms, Hematologic --- Neoplasms, Hematopoietic --- Hematologic Malignancies --- Hematopoietic Neoplasms --- Hematologic Neoplasm --- Hematological Malignancy --- Hematological Neoplasm --- Hematopoietic Malignancy --- Hematopoietic Neoplasm --- Malignancies, Hematological --- Malignancies, Hematopoietic --- Malignancy, Hematological --- Malignancy, Hematopoietic --- Neoplasm, Hematologic --- Neoplasm, Hematological --- Neoplasm, Hematopoietic --- Neoplasms, Hematological --- Haematology --- Body fluids --- Fear of blood --- Internal medicine --- Hematologic Neoplasms --- Pathology --- Blood Cancer --- Blood Cancers --- Cancer, Blood --- Health Sciences --- Hematologia --- Malalties hematològiques

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The mechanistic/mammalian target of rapamycin (mTOR), a serine/threonine kinase, is a central regulator for human physiological activity. Deregulated mTOR signaling is implicated in a variety of disorders, such as cancer, obesity, diabetes, and neurodegenerative diseases. The papers published in this Special Issue summarize the current understanding of the mTOR pathway and its role in the regulation of tissue regeneration, regulatory T cell differentiation and function, and different types of cancer including hematologic malignancies, skin, prostate, breast, and head and neck cancer. The findings highlight that targeting mTOR pathway is a promising strategy to fight against certain human diseases.

mTOR --- histone deacetylase --- prostate cancer --- integrins --- adhesion --- invasion --- cell metabolism --- T cells --- Foxp3 --- Acute Lymphoblastic leukemia --- targeted therapy --- metabolism --- cell signalling --- mTOR signalling --- head and neck cancer --- mutant genes --- biomarkers --- targeted therapies --- clinical trials --- cancers --- inhibitors --- photodynamic therapy --- PI3K --- Akt --- skin cancers --- phytochemicals --- melanoma --- basal cell carcinoma --- squamous cell carcinoma --- Merkel cell carcinoma --- TNBC --- eribulin --- PI3K/AKT/mTOR --- everolimus --- combination --- synergy --- mTOR signaling --- tissue regeneration --- neuron --- muscle --- liver --- intestine --- hematologic malignancies --- regulatory T cells --- tumor