Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Wild animals under human care as well as domesticated farm production animals are often exposed to environmental changes (e.g., capture and transportation). Short-term or acute changes in physiological indices (e.g., heart rate, respiration, body temperatures, immune cells, and stress hormonal biomarkers) provide crucial information regarding the responses of animals to novel environments, and they could provide crucial determining factors for the long-term health and welfare of animals. This Special Issue includes experimental research papers that demonstrate the applications of physiological indices and welfare assessment methods (e.g., morphological and morphometric data, behavioural assessments, thermal profiles, and physiological markers) in any wildlife or production animal (e.g., rescued and rehabilitating animals, pets, competition animals, farm animals, and zoo animals), in response to environmental and management related factors. The goal is to provide examples of new research and techniques that can be used to monitor short- and long-term environmental adaptation of animals under human care.

Research & information: general --- Biology, life sciences --- Zoology & animal sciences --- non-invasive --- bioindicator --- pollution --- stress --- welfare --- constructed wetland --- glucocorticoid --- urban river --- reindeer --- glucocorticoids --- validation --- rodents --- ecological immunology --- natural antibodies --- haptoglobin --- neutrophil to lymphocyte ratio --- immune strategy --- vector-borne pathogens --- parasitology --- zoonosis --- thermal imaging --- koalas --- body temperature --- heat/cold stress --- thermoregulation --- substrate --- Zoo --- protocol --- veterinary assessment --- Punjab urial --- body condition --- behavior --- Pakistan --- red deer --- hind --- reproduction --- progesterone --- cortisol --- hair --- Asian elephant --- saliva --- immunoglobulin A --- circadian rhythm --- Panthera tigris tigris --- Panthera tigris altaica --- siberian --- tigers --- bengal tigers --- captive --- biochemical parameter --- serum protein electrophoresis --- Cervus elaphus --- plasma --- feces --- hunting --- zoo --- faecal analysis --- glucocorticoid metabolites --- enzyme immunoassay --- roe deer --- blood parameters --- prognostic factors --- blood lactate concentration --- biomarkers --- captivity-induced stress --- fecal glucocorticoid metabolites --- physiological stress in rodents --- oxytocin --- boar --- ejaculation --- wildlife --- environmental stress --- urbanisation --- birds --- n/a

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Even though initially considered as a passive means for storing energy, lipids are now regarded as multifaceted molecules with crucial structural and functional activities. For instance, some of them play essential roles as key components of cell membranes whereas others act as signaling molecules in the regulation of cell homeostasis. In recent years, lipid research has attracted increasing interest because of the involvement of this class of compounds in human health. Indeed, a plethora of pathological conditions are characterized by alterations in lipid metabolism, such as cardiovascular diseases and brain disorders. This Special Issue is a collection of papers from different experts in lipid research, with the aim of providing new insights into the physiopathological involvement of lipids and their impact on human health. This collection also demonstrates the usefulness of interdisciplinary approaches in the development of novel methods to study and manipulate lipid metabolism, which may represent an attractive target for designing effective therapeutic strategies to counteract numerous pathologies.

Medicine --- neutral sphingomyelinase --- radiation --- sphingomyelin metabolism --- pathology --- cell signaling --- brain --- adipose tissue --- breast cancer --- epinephrine --- breast reconstruction --- epicardial fat thickness --- visceral fat thickness --- high-sensitivity c-reactive protein --- leptin --- gender --- female --- hippocampus --- frontal cortex --- adiponectin --- haptoglobin --- lipocalin --- BDNF --- synaptic proteins --- phosphatidylinositol 4,5-bisphosphate --- phospholipase C --- cholesterol --- high-cholesterol diet --- BET proteins --- cell proliferation --- epigenetics --- HMGCR --- JQ1 --- LDLr --- lipid metabolism --- SREBP --- TMEM97 --- atherosclerosis --- diabetes mellitus --- cardiovascular disease --- chronic inflammation --- hyperglycemia --- mutations --- lipid --- fatty acid --- glyceride --- steroid --- phospholipid --- oral drug absorption --- prodrug --- phospholipase A2 (PLA2) --- acid sphingomyelinase --- SOD --- liver --- eicosanoids --- ischemic stroke --- ischemia --- lipoproteins --- polyunsaturated fatty acids --- angiogenesis --- high-density lipoprotein --- endothelial cell --- metabolism --- metabolic reprogramming --- pulmonary fibrosis --- lipid mediators --- sphingolipids --- sphingosine-1-phosphate --- sphingosine kinase 1 --- prostaglandins --- lysophosphatidic acid --- autotaxin --- G-protein coupled receptors --- lysocardiolipin acyltransferase --- phospholipase D --- oxidized phospholipids --- DNA damage response --- double strand breaks --- ATM --- ionizing radiation --- metabolic stress --- oxidative stress --- p53 --- nuclear sphingolipids --- lipophagy --- lipolysis --- lipid droplets --- lipid storage diseases --- lipid metabolism diseases --- mTORC1 --- TFEB --- Cholesterol --- Fatty acids --- Lipid mediators --- Lipids --- Lipophagy --- Sphingolipids

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Biomarkers are measures of a biological state. The treatment of individual patients based on particular factors, such as biomarkers, distinguishes standard, generalized treatment plans from personalized medicine. Even though personalized medicine is applicable to most branches of medicine, the field of oncology is perhaps where it is most easily employed. Cancer is a heterogeneous disease; although patients may be diagnosed histologically with the same cancer type, their tumors can comprise varying tumor microenvironments and molecular characteristics that can impact treatment response and prognosis. There has been a major drive over the past decade to try and realize personalized cancer medicine through the discovery and use of disease-specific biomarkers. This book, entitled “Cancer Biomarker Research and Personalized Medicine”, encompasses 22 publications from colleagues working on a diverse range of cancers, including prostate, breast, ovarian, head and neck, liver, gastric, bladder, colorectal, and kidney. The biomarkers assessed in these studies include genes, intracellular or secreted proteins, exosomes, DNA, RNA, miRNA, circulating tumor cells, circulating immune cells, in addition to radiomic features.

Medicine --- Oncology --- clear cell renal cell carcinoma --- radiomics --- WHO/ISUP nuclear grade --- multiphasic multidetector computed tomography --- triple-negative breast cancer --- taxane --- chemotherapy --- GBP5 --- Akt/mTOR --- autophagy --- IL13Rα2 --- renal cell carcinoma --- JAK2 --- FOXO3 --- telmisartan --- ovarian cancer --- bioinformatics --- CREB1 --- drug perturbation --- lincRNA-p21 --- rectal cancer --- chemoradiotherapy --- colorectal cancer --- long non-coding RNA --- p53 --- predictive biomarker --- intestinal anastomosis --- anastomotic leak --- biomarkers --- precision medicine --- personalized medicine --- biomarker --- AmpliSeq --- DNA methylation --- epigenetics --- head and neck cancer --- saliva --- liquid biopsy --- meta-analysis --- gastric cancer --- middle-up-down --- haptoglobin --- glycopeptide --- mass spectrometry --- circulating tumor cells --- prostate cancer --- cancer vaccine --- immune response --- breast cancer --- predictive tools --- prognostic tools --- translational research --- IL6ST --- gp130 --- cytokine signalling --- tissue-based biomarkers --- liquid-based biomarkers --- radiotherapy --- radiosensitivity biomarkers --- secretome --- radioresistance --- bladder tumor --- lymphocyte-to-monocyte ratio --- peripheral blood parameters --- tumor recurrence --- transurethral resection --- lipidomics --- 1H-NMR --- LC-MS/MS --- lipoprotein subfractions --- lipoprotein lipase --- cancer biomarkers --- hepatocellular carcinoma --- p16 expression --- head and neck squamous cell carcinoma --- HPV genotyping --- exosomes --- chemoresistance --- comparative oncology --- One Health --- microRNA --- lymph node metastasis --- hormone-dependent carcinogenesis --- localized prostate cancer --- prognostic factors --- HNSCC --- n/a

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Biomarkers are measures of a biological state. The treatment of individual patients based on particular factors, such as biomarkers, distinguishes standard, generalized treatment plans from personalized medicine. Even though personalized medicine is applicable to most branches of medicine, the field of oncology is perhaps where it is most easily employed. Cancer is a heterogeneous disease; although patients may be diagnosed histologically with the same cancer type, their tumors can comprise varying tumor microenvironments and molecular characteristics that can impact treatment response and prognosis. There has been a major drive over the past decade to try and realize personalized cancer medicine through the discovery and use of disease-specific biomarkers. This book, entitled “Cancer Biomarker Research and Personalized Medicine”, encompasses 22 publications from colleagues working on a diverse range of cancers, including prostate, breast, ovarian, head and neck, liver, gastric, bladder, colorectal, and kidney. The biomarkers assessed in these studies include genes, intracellular or secreted proteins, exosomes, DNA, RNA, miRNA, circulating tumor cells, circulating immune cells, in addition to radiomic features.

clear cell renal cell carcinoma --- radiomics --- WHO/ISUP nuclear grade --- multiphasic multidetector computed tomography --- triple-negative breast cancer --- taxane --- chemotherapy --- GBP5 --- Akt/mTOR --- autophagy --- IL13Rα2 --- renal cell carcinoma --- JAK2 --- FOXO3 --- telmisartan --- ovarian cancer --- bioinformatics --- CREB1 --- drug perturbation --- lincRNA-p21 --- rectal cancer --- chemoradiotherapy --- colorectal cancer --- long non-coding RNA --- p53 --- predictive biomarker --- intestinal anastomosis --- anastomotic leak --- biomarkers --- precision medicine --- personalized medicine --- biomarker --- AmpliSeq --- DNA methylation --- epigenetics --- head and neck cancer --- saliva --- liquid biopsy --- meta-analysis --- gastric cancer --- middle-up-down --- haptoglobin --- glycopeptide --- mass spectrometry --- circulating tumor cells --- prostate cancer --- cancer vaccine --- immune response --- breast cancer --- predictive tools --- prognostic tools --- translational research --- IL6ST --- gp130 --- cytokine signalling --- tissue-based biomarkers --- liquid-based biomarkers --- radiotherapy --- radiosensitivity biomarkers --- secretome --- radioresistance --- bladder tumor --- lymphocyte-to-monocyte ratio --- peripheral blood parameters --- tumor recurrence --- transurethral resection --- lipidomics --- 1H-NMR --- LC-MS/MS --- lipoprotein subfractions --- lipoprotein lipase --- cancer biomarkers --- hepatocellular carcinoma --- p16 expression --- head and neck squamous cell carcinoma --- HPV genotyping --- exosomes --- chemoresistance --- comparative oncology --- One Health --- microRNA --- lymph node metastasis --- hormone-dependent carcinogenesis --- localized prostate cancer --- prognostic factors --- HNSCC --- n/a