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Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of a radical nature, and diverse families of organic compounds, such as (hetero) aromatic rings and aliphatic substrates. Drawing on the authors' expert knowledge, this book provides researchers with a broad set of applicable methods to use in their work. Highlights the latest developments in the field in a concise volume. Provides details of key fluorinating reagents across diverse families of organic compounds. Explores the current applications and future potential of fluorine in drug development.
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AROMATIC COMPOUNDS --- HALOGENATION --- NITRATION --- SUBSTITUTION REACTIONS --- AROMATIC COMPOUNDS --- HALOGENATION --- NITRATION --- SUBSTITUTION REACTIONS
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Chemical kinetics. --- Free radicals (Chemistry) --- Halogenation. --- Free radicals (Chemistry).
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"The Curious World of Fluorinated Molecules: Molecules Containing Fluorine is the sixth volume in the Progress in Fluorine Science series and is edited by the world-renowned scientist Konrad Seppelt. Dr. Seppelt brings together a team of global experts to uncover the multifaceted nature of the most electronegative element in the Periodic Table. The book explores the fascinating world of unpredictable, fluorine-containing molecules through their discoveries, path to recognition, current state of the art, and impact on the broader fields of fluorinated materials development."--
Fluorine. --- Fluorination. --- Chemical reactions --- Halogenation --- Halogens --- Light elements
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Phagocytosis --- Peroxidase --- Halogenation --- Congresses. --- PEROXIDASES, congresses --- LEUKOCYTES, congresses --- HALOGENS, congresses --- Congresses --- Halogenation - Congresses --- Peroxidase - Congresses --- Phagocytosis - Congresses
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Descriptive organic chemistry --- Organic compounds --- Synthesis --- Chemistry, Organic. --- Synthesis. --- Hydrogenation. --- Organic compounds. --- Oxidation. --- Organic compounds - Synthesis --- Addition reaction --- Deuteration --- Halogenation --- Rearrangement (chemistry) --- Substitution
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544.43 --- 66.094.3 --- 665.652.8 --- Chemistry, Organic --- Oxidation --- #WSCH:LOSH --- Autoxidation --- Organic chemistry --- Chemistry --- Mechanism of chemical reactions --- Reaction with various chemicals. Halogenation. Oxidation. Sulphurization --- 665.652.8 Reaction with various chemicals. Halogenation. Oxidation. Sulphurization --- 66.094.3 Oxidation --- Chemistry, Organic. --- Oxidation. --- Copper --- Coupling reaction --- Ruthenium compounds --- Thallium
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