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[Increasing evidence suggests that microbiota and especially the gut microbiota (the microbes inhabiting the gut including bacteria, archaea, viruses, and fungi) plays a key role in human physiology and pathology. Recent findings indicate how dysbiosis—an imbalance in the composition and organization of microbial populations—could severely impact the development of different medical conditions (from metabolic to mood disorders), providing new insights into the comprehension of diverse diseases, such as IBD, obesity, asthma, autism, stroke, diabetes, and cancer. Given that microbial cells in the gut outnumber host cells, microbiota influences human physiology both functionally and structurally. Microbial metabolites bridge various—even distant—areas of the organism by way of the immune and hormone system. For instance, it is now clear that the mutual interaction between the gastrointestinal tract and the brain (gut–brain axis), often involves gut microbiota, indicating that the crosstalk between the organism and its microbial residents represents a fundamental aspect of both the establishment and maintenance of healthy conditions. Moreover, it is crucial to recognize that beyond the intestinal tract, microbiota populates other host organs and tissues (e.g., skin and oral mucosa). We have edited this eBook with the aim of publishing manuscripts focusing on the impact of microbiota in the development of different diseases and their associated treatments.]
gastrointestinal diseases --- sterile inflammation --- n/a --- Staphylococcus spp. --- etiopathogenesis --- colitis --- Escherichia coli --- bacteriophages --- atopic dermatitis --- intravenous immunoglobulin G --- adaptive immunity --- 16S rRNA gene --- vaginal microbiota --- modularity --- innate immunity --- gut-liver axis --- disease activity --- immune system --- cytokines --- commensals --- Staphylococcus aureus --- dysbiosis --- fecal transplantation --- TLR mimicry --- etanercept --- dextran sulfate sodium --- CAR T-cell --- 3-dihydroxy-4-methoxyBenzaldehyde --- chemo free treatment --- Staphylococcus epidermis --- rheumatoid arthritis --- microbiome --- co-occurrence network --- immune epigenetics --- 2 --- autoimmunity --- superoxide dismutase --- precision medicine --- metabolism --- adoptive cell transfer (ACT) --- gut barrier --- antibiotics --- checkpoint inhibitors --- probiotics --- microbiota --- Candida albicans --- Enterococcus faecalis --- chronic liver diseases --- TCR --- anaerobic bacteria --- HSV2 --- bacteriocins --- methotrexate --- microbial interactions --- T cells --- virus --- mice --- lymphoid malignancies --- HPV --- macrophages --- anti-TNF-? --- inflammation --- chondroitin sulfate disaccharide --- immunotherapy --- genomics --- immuno-oncology --- diet --- aerobic bacteria --- immunological niche --- melanin --- health --- chemokines --- gut microbiota --- cutaneous immunity --- HIV --- TIL --- cancer --- global network
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Gut microbiota are an area recently targeted by modern biomedical research. In fact, during the last five years, there has been increasing evidence related to the role of gut microbiota as remarkable symbiotic partners critical for the maintenance of good health. Several factors cause alterations in gut microbiota which are, indeed, accompanied by alterations in the quality of health. Accordingly, gut microbiota dysbiosis has been related to increased susceptibilities to intestinal, cardiovascular, and nervous pathologies. In this manual, you will find the latest studies carried out in the field of microbiota. Overall, the contributions published in this Special Issue further strengthen the essential function of gut microbiota in health and in various diseases.
Public health & preventive medicine --- gut microbiota --- anti-TNFα --- Crohn’s disease --- Faecalibacterium prausnitzii --- Escherichia coli and Clostridium coccoides group --- obesity --- percutaneous electrical stimulation --- dermatome T6 --- microbiota --- probiotics --- resistance --- survivability --- gastrointestinal passage --- gut --- nicotinic acetylcholine receptors --- α7 and α9 nicotinic receptor subtypes --- cholinergic anti-inflammatory pathway --- gut-brain axis --- gut microbiome --- dysbiosis --- inflammatory bowel disease --- COVID-19 --- dioxide titanium --- TiO2 --- E171 --- CI 77891 --- food additive --- gut barrier --- immunity --- toxicity --- diet --- memory --- attention --- gut–brain axis --- gastrointestinal microbiome --- fibromyalgia --- drug therapy --- neoplasms --- radiotherapy --- systematic review --- autoimmunity --- multiple sclerosis --- inflammation --- cytokines --- intestinal permeability --- disease modifying drugs --- food-derived opioids --- casomorphin --- gliadorphin --- opioid receptors --- A1 beta-casein --- beta-casomorphin-7 --- gut-to-brain --- microbiome --- DPP4 --- fecal microbiota --- isoflavones --- equol --- pyrosequencing --- menopause --- fatty acids --- stool --- stool collection --- Cambodia --- sample collection --- rural health --- collection kit --- allergy --- osteoporosis --- bone metabolism --- food allergy --- skeletal health --- osteoimmunology --- n/a --- Crohn's disease
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Supporting initiation, development and resolution of appropriate immune responses is key to survival. Many nutrients and dietary components have been purported to have a role in supporting optimal immune function. This is vital throughout the life course, from the development and programming of the immune system in early life, to supporting immunity and reducing chronic inflammation in older people. In this special issue of Nutrients, we examine the evidence for the role of diet and dietary components in promoting protective immunity.
immunonutrition --- supplementation --- superoxide dismutase (SOD) --- fermented milk --- selenocysteine --- dendritic cells --- lipoxygenase (LOX) --- chronic inflammatory conditions --- formulation --- immune system --- cytokines --- skeletal muscle --- zinc --- non-digestible carbohydrates --- Toll-like receptor --- carbohydrates --- fiber --- lymphocytes --- antibody --- infants --- liver --- macrophage --- inflammatory process --- probiotic --- plant --- older people --- gut barrier --- infection --- amino acids --- gut --- T helper 1 (Th1) --- immunity --- T cells --- bioactive peptide --- inhibitor of kappa kinase (IKK) --- inflammation --- adhesion molecules --- leukocytes --- human milk oligosaccharides --- vitamin D --- food structure --- vitamin E --- mitogen-activated protein Kinase (MAPK) --- gut microbiota --- weaning --- homeostasis --- intestinal immune system --- extra-cellular signal regulated kinases (ERK) --- cyclooxygenase (COX) --- oxidative stress --- life course --- polyphenols --- oligosaccharides --- micronutrients --- Th17 --- obesity --- tolerance --- arachidonic acid --- growth factors --- anti-inflammation --- age-related immunity --- prebiotic --- biomarker --- microbiome --- functional foods --- immunosenescence --- nutrition --- molecular mechanisms --- metabolism --- macronutrients --- toll-like receptor 4 --- sepsis --- nutrition guidelines --- microbiota --- immunomodulation --- inflammatory markers --- elderly --- Th1/Th17 response --- adults --- reactive oxygen species (ROS) --- anorexia nervosa --- macrophages --- autoimmune diseases --- fatty acids --- T cell --- Treg --- breast milk --- nitric oxide synthase (NOS) --- chemokines --- anti-tumorigenic --- metabolites --- deficiency --- protein hydrolysate --- nuclear factor kappa-light-chain-enhancer of activated B cells (NF-?B) --- cancer
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