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Contemporary healthcare trends indicate that many chronic and communicable diseases are related to lifestyle, stress, personal choices and systemic factors. In response to the shortfalls of modern medicine regarding the prevention of these diseases and the promotion of whole-person health, providers and consumers worldwide are exploring integrative, natural and complementary approaches to prevention, treatment and health promotion. These trends harbor the future of medicine. The issues of clinician burnout, high rates of adverse effects, high cost, and lack of rigorous methods to promote individual and collective immunity are addressed by leading physicians and scientists from around the world. The original research and reviews in this volume investigate efficacy, molecular mechanisms and hypotheses that suggest that traditional systems of medicine and health, e.g., Ayurveda, yoga, traditional Chinese medicine, and mind–body–lifestyle medicine, may offer preventive and cost-effective solutions to contemporary health care challenges. Integrating innovative health approaches with conventional medicine offers a whole system of medicine that encompasses the individual, family, community and environment—from single person to planetary health.

Medicine --- asthma --- diagnosis --- treatment strategies --- oxidative stress --- antioxidants --- microbiome --- Ayurveda --- gut bacteria --- diet --- lifestyle --- disease --- prevention --- integrative medicine --- Ayurgenomics --- genomics --- P4 medicine --- personalized medicine --- epigenetics --- genotype --- phenotype --- Prakriti --- doshas --- meditation --- focused attention --- open monitoring --- Transcendental Meditation --- antiviral --- medicinal plants --- pandemic --- SARS-CoV-2 --- zoonotic virus --- Artemisia --- Artemisinin --- ARTs --- phytochemicals --- chronic stress --- transcendental meditation --- gene expression --- energy metabolism --- biological aging --- epigenetic effects --- allostatic load --- complementary medicine --- plastic surgery --- anthroposophic medicine --- pandemic and women --- women and heart disease --- psychological effects of pandemic --- cardiac prevention --- risk of heart disease in women --- hypercholesterolemia --- ayurveda --- ayurvedic herbs --- systematic review --- meta-analysis --- integrative health --- whole-person health --- systems research --- reductionism --- complementary and alternative medicine --- healing --- healthcare transformation --- overview --- stroke --- vegetarian --- vegan --- dosha --- prakriti --- integrative nutrition --- asthma --- diagnosis --- treatment strategies --- oxidative stress --- antioxidants --- microbiome --- Ayurveda --- gut bacteria --- diet --- lifestyle --- disease --- prevention --- integrative medicine --- Ayurgenomics --- genomics --- P4 medicine --- personalized medicine --- epigenetics --- genotype --- phenotype --- Prakriti --- doshas --- meditation --- focused attention --- open monitoring --- Transcendental Meditation --- antiviral --- medicinal plants --- pandemic --- SARS-CoV-2 --- zoonotic virus --- Artemisia --- Artemisinin --- ARTs --- phytochemicals --- chronic stress --- transcendental meditation --- gene expression --- energy metabolism --- biological aging --- epigenetic effects --- allostatic load --- complementary medicine --- plastic surgery --- anthroposophic medicine --- pandemic and women --- women and heart disease --- psychological effects of pandemic --- cardiac prevention --- risk of heart disease in women --- hypercholesterolemia --- ayurveda --- ayurvedic herbs --- systematic review --- meta-analysis --- integrative health --- whole-person health --- systems research --- reductionism --- complementary and alternative medicine --- healing --- healthcare transformation --- overview --- stroke --- vegetarian --- vegan --- dosha --- prakriti --- integrative nutrition

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Contemporary healthcare trends indicate that many chronic and communicable diseases are related to lifestyle, stress, personal choices and systemic factors. In response to the shortfalls of modern medicine regarding the prevention of these diseases and the promotion of whole-person health, providers and consumers worldwide are exploring integrative, natural and complementary approaches to prevention, treatment and health promotion. These trends harbor the future of medicine. The issues of clinician burnout, high rates of adverse effects, high cost, and lack of rigorous methods to promote individual and collective immunity are addressed by leading physicians and scientists from around the world. The original research and reviews in this volume investigate efficacy, molecular mechanisms and hypotheses that suggest that traditional systems of medicine and health, e.g., Ayurveda, yoga, traditional Chinese medicine, and mind–body–lifestyle medicine, may offer preventive and cost-effective solutions to contemporary health care challenges. Integrating innovative health approaches with conventional medicine offers a whole system of medicine that encompasses the individual, family, community and environment—from single person to planetary health.

asthma --- diagnosis --- treatment strategies --- oxidative stress --- antioxidants --- microbiome --- Ayurveda --- gut bacteria --- diet --- lifestyle --- disease --- prevention --- integrative medicine --- Ayurgenomics --- genomics --- P4 medicine --- personalized medicine --- epigenetics --- genotype --- phenotype --- Prakriti --- doshas --- meditation --- focused attention --- open monitoring --- Transcendental Meditation --- antiviral --- medicinal plants --- pandemic --- SARS-CoV-2 --- zoonotic virus --- Artemisia --- Artemisinin --- ARTs --- phytochemicals --- chronic stress --- transcendental meditation --- gene expression --- energy metabolism --- biological aging --- epigenetic effects --- allostatic load --- complementary medicine --- plastic surgery --- anthroposophic medicine --- pandemic and women --- women and heart disease --- psychological effects of pandemic --- cardiac prevention --- risk of heart disease in women --- hypercholesterolemia --- ayurveda --- ayurvedic herbs --- systematic review --- meta-analysis --- integrative health --- whole-person health --- systems research --- reductionism --- complementary and alternative medicine --- healing --- healthcare transformation --- overview --- stroke --- vegetarian --- vegan --- dosha --- prakriti --- integrative nutrition --- n/a

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Many research teams are working to demonstrate that microorganisms can be our daily partners, due to the great diversity of biochemical transformations and molecules they are able to produce. This Special Issue highlights several facets of the production of microbial metabolites of interest. From the discovery of new strains or new bioactive molecules issued from novel environments, to the increase in their synthesis by traditional or innovative methods, different levels of biotechnological processes are addressed. Combining the new dimensions of "Omics" sciences, such as genomics, transcriptomics or metabolomics, microbial biotechnologies are opening up incredible opportunities for discovering and improving microorganisms and their production.

Research & information: general --- Biology, life sciences --- Microbiology (non-medical) --- Docosahexaenoic acid (DHA) --- polyunsaturated fatty acids (PUFAs) --- mutant strain --- Aurantiochytrium sp. --- transcriptome --- Xanthomonas campestris pv. campestris --- 6-pentyl-α-pyrone --- antibiosis --- Trichoderma --- secondary metabolites --- antibiofilm --- Gram-negative bacterium --- antibiotic resistance --- natural products --- angucycline --- aquayamycin --- glycosyltransferase --- Lake Baikal --- Streptomyces --- Talaromyces albobiverticillius 30548 --- submerged fermentation --- pigments --- biomass --- optimization --- Box–Behnken experimental design --- response surface modeling --- carnosic acid --- propolis --- antifungal action --- synergy --- Candida albicans --- biofilms --- sponges --- actinomycetes --- cryptic --- Micromonospora --- Nocardia --- Gordonia --- mycolic acid --- LC-HRESIMS --- N-functionalized amines --- N-methylanthranilate --- Corynebacterium glutamicum --- metabolic engineering --- sustainable production of quinoline precursors --- acridone --- quinazoline alkaloid drugs --- SARS-CoV-2 --- Covid-19 --- Mpro --- microbial natural products --- docking --- molecular dynamic simulation --- Serratiochelin A --- Serratiochelin C --- Serratia sp. --- siderophore --- iron --- anticancer --- microbial biotechnology --- degradation --- antibacterial --- S. aureus --- sparkling wine --- second fermentation --- fermentation by-products --- Saccharomyces cerevisiae flor yeast --- proteins --- Scopalina hapalia --- Actinomycetes --- Bacillus --- Fungi --- elastase inhibition --- tyrosinase inhibition --- CDK7 inhibition --- Fyn kinase inhibition --- catalase activation --- sirtuin 1 activation --- Curvularia papendorfii --- endophytic fungi --- human coronavirus HCoV 229E --- Staphylococcus sp. --- MRSA --- antiproliferative activity --- polyhydroxyacid --- kheiric acid --- insect --- mealworm --- gut bacteria --- OSMAC --- cyclic peptides --- biosynthetic pathway --- autophagy inducer --- fermentation --- Lactococcus lactis --- bacteriocin --- culture conditions --- medium compositions --- lactic acid fermentation --- Pediococcus acidilactici PA204 --- simultaneous saccharification and fermentation --- corn stover --- pyocyanin --- maize industry wastewater --- Pseudomonas aeruginosa NEJ01R --- redox metabolite --- response surface analysis --- bioproduction --- valorization --- electrochemical analysis --- sugarcane --- distillery waste water --- molasses spent wash --- vinasse --- fungi --- yeasts --- bioremediation --- COD --- discoloration --- antimicrobial --- antioxidant --- GNPS --- textiles --- cation-exchange resin --- adsorption --- removal --- ammonium --- cell viability --- mutant gdhA P. multocida B:2 --- cyanobacteria --- photosynthesis --- synthetic biology --- systems biology --- genome-scale model --- protoplast fusion --- novel compound discovery --- cell wall-deficiency --- heteroploidy --- Talaromyces --- azaphilone --- marine fungi --- N-threonyl-rubropunctamin --- PP-R --- greener extraction --- red pigments --- fungal pigments --- antinematode compound --- anthelminthic drugs --- marine epiphytic bacteria --- marine biofilm --- marine environment --- parasitic nematode --- Caenorhabditis elegans --- natural colors --- bio-pigments --- quorum sensing --- marine bacteria --- biosynthesis --- biological activities --- industrial applications --- therapeutic insights --- global pigment market --- terpenoids --- sesquiterpene production --- Rhodobacter capsulatus --- β-caryophyllene --- bioactivity --- phytopathogens --- plant pathogenic fungi --- plant growth-promoting bacteria --- microorganisms --- biotechnology --- screening --- production --- extraction --- bioactive properties --- perspectives --- Docosahexaenoic acid (DHA) --- polyunsaturated fatty acids (PUFAs) --- mutant strain --- Aurantiochytrium sp. --- transcriptome --- Xanthomonas campestris pv. campestris --- 6-pentyl-α-pyrone --- antibiosis --- Trichoderma --- secondary metabolites --- antibiofilm --- Gram-negative bacterium --- antibiotic resistance --- natural products --- angucycline --- aquayamycin --- glycosyltransferase --- Lake Baikal --- Streptomyces --- Talaromyces albobiverticillius 30548 --- submerged fermentation --- pigments --- biomass --- optimization --- Box–Behnken experimental design --- response surface modeling --- carnosic acid --- propolis --- antifungal action --- synergy --- Candida albicans --- biofilms --- sponges --- actinomycetes --- cryptic --- Micromonospora --- Nocardia --- Gordonia --- mycolic acid --- LC-HRESIMS --- N-functionalized amines --- N-methylanthranilate --- Corynebacterium glutamicum --- metabolic engineering --- sustainable production of quinoline precursors --- acridone --- quinazoline alkaloid drugs --- SARS-CoV-2 --- Covid-19 --- Mpro --- microbial natural products --- docking --- molecular dynamic simulation --- Serratiochelin A --- Serratiochelin C --- Serratia sp. --- siderophore --- iron --- anticancer --- microbial biotechnology --- degradation --- antibacterial --- S. aureus --- sparkling wine --- second fermentation --- fermentation by-products --- Saccharomyces cerevisiae flor yeast --- proteins --- Scopalina hapalia --- Actinomycetes --- Bacillus --- Fungi --- elastase inhibition --- tyrosinase inhibition --- CDK7 inhibition --- Fyn kinase inhibition --- catalase activation --- sirtuin 1 activation --- Curvularia papendorfii --- endophytic fungi --- human coronavirus HCoV 229E --- Staphylococcus sp. --- MRSA --- antiproliferative activity --- polyhydroxyacid --- kheiric acid --- insect --- mealworm --- gut bacteria --- OSMAC --- cyclic peptides --- biosynthetic pathway --- autophagy inducer --- fermentation --- Lactococcus lactis --- bacteriocin --- culture conditions --- medium compositions --- lactic acid fermentation --- Pediococcus acidilactici PA204 --- simultaneous saccharification and fermentation --- corn stover --- pyocyanin --- maize industry wastewater --- Pseudomonas aeruginosa NEJ01R --- redox metabolite --- response surface analysis --- bioproduction --- valorization --- electrochemical analysis --- sugarcane --- distillery waste water --- molasses spent wash --- vinasse --- fungi --- yeasts --- bioremediation --- COD --- discoloration --- antimicrobial --- antioxidant --- GNPS --- textiles --- cation-exchange resin --- adsorption --- removal --- ammonium --- cell viability --- mutant gdhA P. multocida B:2 --- cyanobacteria --- photosynthesis --- synthetic biology --- systems biology --- genome-scale model --- protoplast fusion --- novel compound discovery --- cell wall-deficiency --- heteroploidy --- Talaromyces --- azaphilone --- marine fungi --- N-threonyl-rubropunctamin --- PP-R --- greener extraction --- red pigments --- fungal pigments --- antinematode compound --- anthelminthic drugs --- marine epiphytic bacteria --- marine biofilm --- marine environment --- parasitic nematode --- Caenorhabditis elegans --- natural colors --- bio-pigments --- quorum sensing --- marine bacteria --- biosynthesis --- biological activities --- industrial applications --- therapeutic insights --- global pigment market --- terpenoids --- sesquiterpene production --- Rhodobacter capsulatus --- β-caryophyllene --- bioactivity --- phytopathogens --- plant pathogenic fungi --- plant growth-promoting bacteria --- microorganisms --- biotechnology --- screening --- production --- extraction --- bioactive properties --- perspectives