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This report by the World Health Organization discusses an informal consultation on methodologies to differentiate reinfection from recrudescence in areas with high malaria transmission. The report covers the complexities of distinguishing between these two occurrences following treatment of Plasmodium falciparum malaria, particularly in Africa's high transmission regions. It explores different genotyping methodologies, including amplicon sequencing and traditional marker methods, assessing their advantages and limitations. The report emphasizes the importance of accurate classification for evaluating antimalarial drug efficacy and guiding treatment policies. The intended audience includes researchers, healthcare professionals, and policymakers involved in malaria control and treatment.
Malaria. --- Genetic markers. --- Malaria --- Genetic markers
Book
Publisher: [S.l.] : Rennes : Rennes : AUPELF-UREF ; CNED (Centre National d'Enseignement à Distance) ; Institut de Rennes.
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genetic markers --- uses
Book
ISBN: 9789179299569 Year: 2019 Publisher: Linkopings Universitet
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This dissertation by Delmy Oliva focuses on predicting side effects from anticancer treatments to enhance patients' quality of life. It explores the genetic factors contributing to individual variations in experiencing side effects such as nausea, acute skin reactions, and sleep disturbances associated with cancer therapy. The research identifies biological markers that could help in predicting and managing these side effects, thereby personalizing treatment and care. The work aims to improve health-related quality of life by linking symptoms to genetic markers. It is intended for healthcare professionals and researchers in oncology and medical sciences.
Genetic markers. --- Quality of life. --- Genetic markers --- Quality of life
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Book
Year: 2015 Publisher: Reston, Virginia : U.S. Department of the Interior, U.S. Geological Survey,
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Article
Year: 1997 Publisher: [S.l.] : [s.n.],
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Cattle --- genetic markers --- identification. --- identification
Dissertation
ISBN: 9058082733 Year: 2000 Publisher: Wageningen : Wageningen University,
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chickens --- genetic maps --- genetic markers
Dissertation
Year: 2002
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Efficient molecular tools were developed for the identification and certification of about fifty apple varieties and rootstocks from the Belgian cultivar panel. The RFLP method allowed the distinction of 45 from the 49 tested apple tree varieties, on basis of 21 polymorphic fragments revealed by three probe-restriction enzyme combinations. The AFLP technique allowed the distinction of all the tested varieties, on basis of 46 polymorphic fragments revealed by two amplification profiles. Its efficiency is similar to that of the "Simple Sequence Repeats" technique in the distinction of color mutants from the Jonagold variety. Nevertheless, it revealed an existing genetic instability of this variety and its tested mutants. Besides, the "differential display" technique, applied to messenger RNA extracted from fruit epidermis, didn't reveal expression polymorphism that can be used for the distinction of the studied mutants. However, this technique highlighted the presence of an apple gene similar to that coding for the reverse transcriptase from a copia retrotransposon. It was briefly identified and characterized in apple as well as in different plant species representing the Rosaceae family.
Malus --- Varieties --- Rootstocks --- genetic markers
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