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Quatrième de couverture : "La dissection anatomique et l'anatomopathologie furent pendant longtemps les seules méthodes rendant le cerveau humain accessible en dehors des données cliniques recueillies après les lésions accidentelles ou les ablations (lobotomies), ainsi que certaines prouesses neurochirurgicales (neurostimulation). Cet ouvrage collectif s'intéresse plus spécialement à l'évolution des techniques d'exploration cérébrale au cours de l'histoire récente, essentiellement aux XXe et XXIe siècles. Il s'agit de comprendre l'apparition des nouveaux outils, d'aborder le cerveau dans les méandres instrumentaux de son histoire scientifique, de l'animal à l'homme, du structural au fonctionnel. L'histoire de l'exploration du cerveau humain est envisagée selon trois perspectives fondatrices : le renouveau de l'exploration anatomique, l'exploration bioélectrique et biomagnétique et l'exploration par imagerie fonctionnelle."

Electroencephalography --- Neurosciences --- Brain --- Cerveau --- History --- Imaging --- Diseases --- Diagnosis --- Imagerie --- Histoire --- Maladies --- Diagnostic --- Functional Neuroimaging --- history --- Functional Neuroimaging - history --- Neurosciences - history

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The role of nutrition in health and disease has been appreciated from time immemorial. Around 400 B.C., Hippocrates wrote “Let food by thy medicine and medicine be thy food.” In the 12th century, the great philosopher and physician Moses Maimonides wrote “any disease that can be treated by diet should be treated by no other means.” Now, in the 21st century, we are bombarded by claims in the media of “superfoods,” wondrous nutritional supplements, and special diets that promise to cure or prevent disease, improve health and restore functioning. Much of the focus has been on neurological disease, brain health and psychological functioning (behavior, cognition, and emotion). The hyperbole aside, there has been considerable progress in the past decade in our understanding of the contribution of specific nutrients and dietary patterns to brain development, physiology, and functioning. This Special Issue of Brain Sciences is devoted to the latest research on the role of nutritional deficiencies and excesses in the genesis of brain dysfunction, and use of diet for the prevention and treatment of brain and mental disorders. Basic laboratory and clinical research studies of the immature, adult, and aged nervous system are all welcome.

epilepsy --- glioblastoma multiforme --- ADHD --- n/a --- prefrontal cortex --- regainers --- functional neuroimaging --- malignant glioma --- nutrients --- caffeine --- children --- inflammation --- working memory --- cytokines --- modified Atkins diet --- fish intake --- insulin resistance --- transpulmonary administration --- obesity --- maintainers --- electroencephalography --- Alzheimer’s disease --- omega-3 fatty acids --- diet-deficient --- weight loss maintenance --- neural processing --- hippocampal neurogenesis --- Brain --- Diseases --- Diet therapy. --- Cerebrum --- Mind --- Central nervous system --- Head --- Alzheimer's disease

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In the last decade, several different optical imaging techniques, either based on various voltage or calcium dyes, or more recently on modified fluorescent or bioluminescent proteins (genetically encoded) that are sensitive to calcium, have been developed to study neuronal activity, and especially groups of neurons, with the goal of mapping and deciphering the neural code underlying major neurophysiological functions.  Genetically Encoded Functional Indicators brings together expert contributors to present the development of recent genetic techniques that allow for generating genetically encoded activity sensors in order to investigate neuronal activity. Each chapter describes a specific sensor and its utilization to study neuronal activity in a particular way.  Written in the Neuromethods series style, chapters contain the kind of key description and implementation advice that guarantees successful results.   Helpful and easy to use, Genetically Encoded Functional Indicators aims to inspire students and researchers and to serve as a useful guide to those who wish to start using these different brain imaging techniques and require a bit of guidance in how best to choose a technique to match the goal of their study.

Neurosciences. --- Human genetics. --- Neurology. --- Human Genetics. --- Medicine --- Nervous system --- Neuropsychiatry --- Genetics --- Heredity, Human --- Human biology --- Physical anthropology --- Neural sciences --- Neurological sciences --- Neuroscience --- Medical sciences --- Diseases --- Fluorometry. --- Functional Neuroimaging --- Fluorescent Dyes. --- Fluorescence Agents --- Fluorescent Agents --- Fluorogenic Substrate --- Fluorescent Probes --- Fluorochromes --- Agents, Fluorescence --- Agents, Fluorescent --- Dyes, Fluorescent --- Probes, Fluorescent --- Substrate, Fluorogenic --- Luminescent Agents --- Fluorometric Analysis --- Fluorimetry --- Analysis, Fluorometric --- methods. --- Flourescent Agent --- Fluorescent Dye --- Fluorescent Probe --- Fluorochrome --- Fluorogenic Substrates --- Substrates, Fluorogenic