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Zika virus. --- Zika Virus --- Virus, Zika --- ZikV --- Flaviviruses

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This reprint covers different aspects of the West Nile virus (WNV), a mosquito-borne pathogen that belongs to the Flavivirus genus (family Flaviviridae). The virus is maintained in nature in a rural cycle between mosquito vectors, mainly Culex species, and avian hosts. Spillover from this cycle occasionally results in outbreaks in horses and humans. In severe cases, the infection can induce neurological signs, such as meningitis and encephalitis, and in some cases, it can lead to death. The virus has spread across the world in this century, including its expansion in the Americas since 1999, and an increase in the number of outbreaks and its severity has been observed in Europe in recent years. Considering all these aspects, an approach including public, animal and environmental health is the best option to increase the knowledge of this problem, making this disease an excellent example of a "One Health" issue. Bearing in mind this multidisciplinary aspect, the volume includes contributions related to the pathogenesis, vaccines, diagnosis and epidemiology of the virus both in humans and animals.

West Nile virus. --- Egypt 101 virus --- Kunjin virus --- Flaviviruses

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This unique volume presents an up-to-date review of one of the world's major health problems - diseases caused by the four dengue viruses. It begins with an insightful story of the origin of dengue disease outbreaks, including the emergence of severe and fatal dengue hemorrhagic fever. The nature, structure and biology of the four dengue viruses are described, and a major portion of the book is focused on the epidemiology of dengue as a mosquito-borne disease. This is complemented by critiques of existing mosquito control programs by three groups of outstanding authorities. The strongest element of the volume is its comprehensive description of the current understanding of dengue disease pathogenesis, followed by an analysis of the pros and cons of five of the most controversial areas in the field: the WHO DEF case definition, secondary dengue infections, virulent viruses, the role of abnormal T cells and autoimmunity.

Dengue. --- Dengue viruses. --- Flaviviruses --- Breakbone fever --- Dengue fever --- Arbovirus infections --- Flaviviral diseases --- Hemorrhagic fever

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Communicable diseases. --- Zika virus. --- Flaviviruses --- Contagion and contagious diseases --- Contagious diseases --- Infectious diseases --- Microbial diseases in human beings --- Zymotic diseases --- Diseases --- Infection --- Epidemics

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Hepatitis C infects 170 million people worldwide, and has been labelled the 'silent epidemic' as a result of its concealed attack on the liver. This multidisciplinary overview covers basic concepts related to the discovery of the virus, development of serological and nucleic acid tests to detect infection, the structure of the virus genome, generation of virus gene products, and proposed replication scheme. It then goes on to introduce the epidemiology, transmission, pathogenesis of infection, the development of hepatocellular carcinoma associated with chronic virus infection, and current strategies for treatment. The book then discusses advances in cell culture systems, animal models of infection, and emerging treatments and vaccine development. Through its coverage of basic science, clinical consequences, and methods of research, this integrated and accessible account will be of immense value to biomedical scientists and clinicians alike, and a useful introduction for all those studying the virus and its effects.

Hepatitis C. --- Hepatitis C virus. --- HCV (Hepatitis C virus) --- Flaviviruses --- Hepatitis viruses --- Hepatitis, Non-A, non-B --- Non-A, non-B hepatitis, Parenterally-transmitted --- Parenterally-transmitted non-A, non-B hepatitis --- Flaviviral diseases --- Hepatitis, Viral