Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Mithra Pharmaceuticals is currently embracing many challenges and thereby questions the stature of its present supply chain network as well as the responsibility of each stakeholder.
The business environment of the healthcare industry has significantly changed in the past decade putting a tremendous price pressure and strengthening competition among life science companies. Beyond a stricter regulatory scrutiny, contract manufacturing operators impose rigorous constraints leading to long lead times with regards to products’ shelf life and large minimum order quantities. Therefore, supply chain is viewed as a new strategic asset and becomes a potential competitive advantage rather than an unavoidable cost center embedded in daily operations.
For what is more, Mithra recently started an international expansion and is aware that the current supply chain network might represent a burden to the successful accomplishment of its ambitions. In addition to that, Mithra’s future state-of-the-art technologic R&D and manufacturing platform is likely to bring changes and innovations in the way Mithra produces and commercializes its products, reducing the production dependency on third parties.
In this context, this project thesis aims at studying two potential alternatives to Mithra’s current distribution patterns. One the one hand, it will address a problem of network design and facility location to determine whether Mithra should move on to a centralized distribution model with a single warehouse taking roots in Liège Airport or not. Indeed, nowadays, the firm has a decentralized model including four local distribution centers. One the other hand, I will work on postponement concepts for Mithra’s production process. The objective will be to determine the best suited postponement strategy with regards to Mithra’s products portfolio. In both scenarios, I will evaluate the financial impact of such models.

healthcare industry, supply chain network optimization, centralized distribution strategy, facility location problem, postponement strategies. --- Sciences économiques & de gestion > Production, distribution & gestion de la chaîne logistique

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

With the Internet of Things and various information and communication technologies, a city can manage its assets in a smarter way, constituting the urban development vision of a smart city. This facilitates a more efficient use of physical infrastructure and encourages citizen participation. Smart energy and smart mobility are among the key aspects of the smart city, in which the electric vehicle (EV) is believed to take a key role. EVs are powered by various energy sources or the electricity grid. With proper scheduling, a large fleet of EVs can be charged from charging stations and parking infrastructures. Although the battery capacity of a single EV is small, an aggregation of EVs can perform as a significant power source or load, constituting a vehicle-to-grid (V2G) system. Besides acquiring energy from the grid, in V2G, EVs can also support the grid by providing various demand response and auxiliary services. Thanks to this, we can reduce our reliance on fossil fuels and utilize the renewable energy more effectively. This Special Issue “Smart Energy and Intelligent Transportation Systems” addresses existing knowledge gaps and advances smart energy and mobility. It consists of five peer-reviewed papers that cover a range of subjects and applications related to smart energy and transportation.

electric vehicles --- PROSA --- PROMETHEE for Sustainability Assessment --- MCDA --- Multi-Criteria Decision Analysis --- stochastic analysis --- Monte Carlo --- uncertainty --- cargo bicycles --- loading hub --- facility location problem --- computer simulations --- Python programing --- electric vehicle charging --- vehicle-to-grid --- genetic algorithms --- particle swarm optimization --- demand-side management --- discrete choice theory --- revenue management --- road–railway accidents --- classification trees --- road safety --- transport means --- accidents victims --- condition monitoring --- vibroacoustic diagnostics --- gearbox --- power transmission systems --- neural networks --- deep learning --- n/a --- road-railway accidents

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Applied mathematics and symmetry work together as a powerful tool for problem reduction and solving. We are communicating applications in probability theory and statistics (A Test Detecting the Outliers for Continuous Distributions Based on the Cumulative Distribution Function of the Data Being Tested, The Asymmetric Alpha-Power Skew-t Distribution), fractals - geometry and alike (Khovanov Homology of Three-Strand Braid Links, Volume Preserving Maps Between p-Balls, Generation of Julia and Mandelbrot Sets via Fixed Points), supersymmetry - physics, nanostructures -chemistry, taxonomy - biology and alike (A Continuous Coordinate System for the Plane by Triangular Symmetry, One-Dimensional Optimal System for 2D Rotating Ideal Gas, Minimal Energy Configurations of Finite Molecular Arrays, Noether-Like Operators and First Integrals for Generalized Systems of Lane-Emden Equations), algorithms, programs and software analysis (Algorithm for Neutrosophic Soft Sets in Stochastic Multi-Criteria Group Decision Making Based on Prospect Theory, On a Reduced Cost Higher Order Traub-Steffensen-Like Method for Nonlinear Systems, On a Class of Optimal Fourth Order Multiple Root Solvers without Using Derivatives) to specific subjects (Facility Location Problem Approach for Distributed Drones, Parametric Jensen-Shannon Statistical Complexity and Its Applications on Full-Scale Compartment Fire Data). Diverse topics are thus combined to map out the mathematical core of practical problems.

History of engineering & technology --- Khovanov homology --- braid link --- Jones polynomial --- drone deployment --- drone port --- traveling salesman --- facility location problem --- molecular arrays --- constrained optimization --- equivariant bifurcation theory --- generalized Lane–Emden systems --- Noether-like operator --- conservation laws --- barycentric coordinate system --- coordinate system --- hexagonal grid --- triangular grid --- tri-hexagonal grid --- transformations --- test for outliers --- order statistics --- extreme values --- confidence intervals --- Monte-Carlo simulation --- nonlinear equations --- systems --- derivative-free methods --- fast algorithms --- computational efficiency --- neutrosophic soft sets --- inconsistent information --- prospect theory --- stochastic multi-criteria group decision making --- lie symmetries --- invariants --- shallow water --- similarity solutions --- optimal system --- equal volume projection --- hierarchical grid --- iterative function --- multiple root --- composite method --- derivative-free method --- optimal convergence --- full-scale fire experiment --- compartment fire --- permutation entropy --- two length permutation entropy --- time series analysis --- parametric Jensen-Shannon statistical complexity --- symmetric duality --- alpha-power skew-t distribution --- skew-t distribution --- power-t distribution --- asymmetry --- Fisher information matrix --- maximum likelihood estimation --- iteration --- fixed points --- fractals

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Applied mathematics and symmetry work together as a powerful tool for problem reduction and solving. We are communicating applications in probability theory and statistics (A Test Detecting the Outliers for Continuous Distributions Based on the Cumulative Distribution Function of the Data Being Tested, The Asymmetric Alpha-Power Skew-t Distribution), fractals - geometry and alike (Khovanov Homology of Three-Strand Braid Links, Volume Preserving Maps Between p-Balls, Generation of Julia and Mandelbrot Sets via Fixed Points), supersymmetry - physics, nanostructures -chemistry, taxonomy - biology and alike (A Continuous Coordinate System for the Plane by Triangular Symmetry, One-Dimensional Optimal System for 2D Rotating Ideal Gas, Minimal Energy Configurations of Finite Molecular Arrays, Noether-Like Operators and First Integrals for Generalized Systems of Lane-Emden Equations), algorithms, programs and software analysis (Algorithm for Neutrosophic Soft Sets in Stochastic Multi-Criteria Group Decision Making Based on Prospect Theory, On a Reduced Cost Higher Order Traub-Steffensen-Like Method for Nonlinear Systems, On a Class of Optimal Fourth Order Multiple Root Solvers without Using Derivatives) to specific subjects (Facility Location Problem Approach for Distributed Drones, Parametric Jensen-Shannon Statistical Complexity and Its Applications on Full-Scale Compartment Fire Data). Diverse topics are thus combined to map out the mathematical core of practical problems.

History of engineering & technology --- Khovanov homology --- braid link --- Jones polynomial --- drone deployment --- drone port --- traveling salesman --- facility location problem --- molecular arrays --- constrained optimization --- equivariant bifurcation theory --- generalized Lane–Emden systems --- Noether-like operator --- conservation laws --- barycentric coordinate system --- coordinate system --- hexagonal grid --- triangular grid --- tri-hexagonal grid --- transformations --- test for outliers --- order statistics --- extreme values --- confidence intervals --- Monte-Carlo simulation --- nonlinear equations --- systems --- derivative-free methods --- fast algorithms --- computational efficiency --- neutrosophic soft sets --- inconsistent information --- prospect theory --- stochastic multi-criteria group decision making --- lie symmetries --- invariants --- shallow water --- similarity solutions --- optimal system --- equal volume projection --- hierarchical grid --- iterative function --- multiple root --- composite method --- derivative-free method --- optimal convergence --- full-scale fire experiment --- compartment fire --- permutation entropy --- two length permutation entropy --- time series analysis --- parametric Jensen-Shannon statistical complexity --- symmetric duality --- alpha-power skew-t distribution --- skew-t distribution --- power-t distribution --- asymmetry --- Fisher information matrix --- maximum likelihood estimation --- iteration --- fixed points --- fractals