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Mens sana in corpore sano (a healthy mind in a healthy body) is a Latin phrase taken from Giovenale (Satire, X, 356) that remains relevant and is supported by today’s data regarding genetics and nutrition, and their contribution to mental health. The purpose of this Special Issue on “Nutrition and Fitness: Mental Health” is to provide an update on the latest evidence regarding the association between nutrition, physical activity (and inactivity) and physical fitness, and the mental health of children, adolescents, and adults. Particularly, papers (reviews and clinical or experimental studies) dealing with the association between nutrition, physical fitness, and mental health both in general and with regard to specific mental disorders, and nutrients and physical activity as agents for prevention, treatment, or augmentation of treatment for mental disorders, will be included.

Medicine --- depressive symptoms --- food insecurity --- nutrition --- adults --- generalized estimating equation --- review --- eating disorders --- physical activity --- problematic use of physical activity --- multiple sclerosis --- epigallocatechin gallate --- coconut oil --- interleukin-6 --- anxiety --- disability --- mental health --- emotional exhaustion --- cynicism --- professional efficacy --- sedentary behavior --- dietary behavior --- macronutrients --- energy intake --- motivation to diet --- motivation to exercise --- weight loss program --- obesity --- physical performance --- network analysis --- vitality --- psychiatry --- schizophrenia --- depression --- microbiota --- transplantation --- depressive symptoms --- food insecurity --- nutrition --- adults --- generalized estimating equation --- review --- eating disorders --- physical activity --- problematic use of physical activity --- multiple sclerosis --- epigallocatechin gallate --- coconut oil --- interleukin-6 --- anxiety --- disability --- mental health --- emotional exhaustion --- cynicism --- professional efficacy --- sedentary behavior --- dietary behavior --- macronutrients --- energy intake --- motivation to diet --- motivation to exercise --- weight loss program --- obesity --- physical performance --- network analysis --- vitality --- psychiatry --- schizophrenia --- depression --- microbiota --- transplantation

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Mens sana in corpore sano (a healthy mind in a healthy body) is a Latin phrase taken from Giovenale (Satire, X, 356) that remains relevant and is supported by today’s data regarding genetics and nutrition, and their contribution to mental health. The purpose of this Special Issue on “Nutrition and Fitness: Mental Health” is to provide an update on the latest evidence regarding the association between nutrition, physical activity (and inactivity) and physical fitness, and the mental health of children, adolescents, and adults. Particularly, papers (reviews and clinical or experimental studies) dealing with the association between nutrition, physical fitness, and mental health both in general and with regard to specific mental disorders, and nutrients and physical activity as agents for prevention, treatment, or augmentation of treatment for mental disorders, will be included.

depressive symptoms --- food insecurity --- nutrition --- adults --- generalized estimating equation --- review --- eating disorders --- physical activity --- problematic use of physical activity --- multiple sclerosis --- epigallocatechin gallate --- coconut oil --- interleukin-6 --- anxiety --- disability --- mental health --- emotional exhaustion --- cynicism --- professional efficacy --- sedentary behavior --- dietary behavior --- macronutrients --- energy intake --- motivation to diet --- motivation to exercise --- weight loss program --- obesity --- physical performance --- network analysis --- vitality --- psychiatry --- schizophrenia --- depression --- microbiota --- transplantation --- n/a

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This book “Oxidative Stress Modulators and Functional Foods” is focused on the antioxidant role of natural products, involving their ability to modulate oxidative stress and/or reverse disease studied both in vitro and in animal models. Additionally, the molecular mechanisms of these actions and the modulation of signalling pathways related to inflammation, apoptosis, and survival response in the redox system by natural products are included.

high sugar-fat diet --- obesity --- β-adrenergic system --- cardiac dysfunction --- lycopene --- tomato-oleoresin --- coumarin --- pteryxin --- HO-1 --- Nrf2 --- oxidative stress --- Peucedanum japonicum Thunb --- RAW264.7 cells --- polysaccharide --- jujube pomace --- structural analysis --- antioxidant activity --- epigallocatechin-gallate --- liposomes --- diabetes mellitus --- antioxidant --- dendrimer --- electronic effect --- hydrogen atom transfer (HAT) --- single electron transfer-proton transfer (SET-PT) --- sequential proton loss electron transfer (SPLET) --- DPPH --- ultraviolet B --- gradient ethanol precipitation --- fucoidan --- HaCaT keratinocyte --- heme oxygenase-1 --- nutricosmetic --- folic acid --- nitric oxide --- neural tube defects --- NOR3 --- ESR --- LC/MS --- Benzo[a]pyrene --- myricetin --- BPDE-DNA adduct --- phase detoxifying enzyme --- Quamoclit angulata --- type 2 diabetes --- kidney damage --- inflammation --- apoptosis --- fibrosis --- Sargassum horneri --- (–)-loliolide --- fine dust --- HaCaT --- bilberry --- lingonberry --- polyphenols --- antioxidant compounds --- antimicrobial activity --- antimutagenicity --- altitude variations --- mitochondria --- neurodegeneration --- nutrient --- QM-ORSA --- antioxidative mechanisms --- reaction rate constants --- physiological conditions --- zebrafish embryo --- in vivo model --- antioxidant effect --- cudratrixanthone O --- reactive oxygen species --- nuclear transcription factor erythroid-2-like factor 2 --- hemeoxygenase-1 --- n/a --- (-)-loliolide

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This book “Oxidative Stress Modulators and Functional Foods” is focused on the antioxidant role of natural products, involving their ability to modulate oxidative stress and/or reverse disease studied both in vitro and in animal models. Additionally, the molecular mechanisms of these actions and the modulation of signalling pathways related to inflammation, apoptosis, and survival response in the redox system by natural products are included.

Medicine --- Pharmaceutical industries --- high sugar-fat diet --- obesity --- β-adrenergic system --- cardiac dysfunction --- lycopene --- tomato-oleoresin --- coumarin --- pteryxin --- HO-1 --- Nrf2 --- oxidative stress --- Peucedanum japonicum Thunb --- RAW264.7 cells --- polysaccharide --- jujube pomace --- structural analysis --- antioxidant activity --- epigallocatechin-gallate --- liposomes --- diabetes mellitus --- antioxidant --- dendrimer --- electronic effect --- hydrogen atom transfer (HAT) --- single electron transfer-proton transfer (SET-PT) --- sequential proton loss electron transfer (SPLET) --- DPPH --- ultraviolet B --- gradient ethanol precipitation --- fucoidan --- HaCaT keratinocyte --- heme oxygenase-1 --- nutricosmetic --- folic acid --- nitric oxide --- neural tube defects --- NOR3 --- ESR --- LC/MS --- Benzo[a]pyrene --- myricetin --- BPDE-DNA adduct --- phase detoxifying enzyme --- Quamoclit angulata --- type 2 diabetes --- kidney damage --- inflammation --- apoptosis --- fibrosis --- Sargassum horneri --- (-)-loliolide --- fine dust --- HaCaT --- bilberry --- lingonberry --- polyphenols --- antioxidant compounds --- antimicrobial activity --- antimutagenicity --- altitude variations --- mitochondria --- neurodegeneration --- nutrient --- QM-ORSA --- antioxidative mechanisms --- reaction rate constants --- physiological conditions --- zebrafish embryo --- in vivo model --- antioxidant effect --- cudratrixanthone O --- reactive oxygen species --- nuclear transcription factor erythroid-2-like factor 2 --- hemeoxygenase-1 --- high sugar-fat diet --- obesity --- β-adrenergic system --- cardiac dysfunction --- lycopene --- tomato-oleoresin --- coumarin --- pteryxin --- HO-1 --- Nrf2 --- oxidative stress --- Peucedanum japonicum Thunb --- RAW264.7 cells --- polysaccharide --- jujube pomace --- structural analysis --- antioxidant activity --- epigallocatechin-gallate --- liposomes --- diabetes mellitus --- antioxidant --- dendrimer --- electronic effect --- hydrogen atom transfer (HAT) --- single electron transfer-proton transfer (SET-PT) --- sequential proton loss electron transfer (SPLET) --- DPPH --- ultraviolet B --- gradient ethanol precipitation --- fucoidan --- HaCaT keratinocyte --- heme oxygenase-1 --- nutricosmetic --- folic acid --- nitric oxide --- neural tube defects --- NOR3 --- ESR --- LC/MS --- Benzo[a]pyrene --- myricetin --- BPDE-DNA adduct --- phase detoxifying enzyme --- Quamoclit angulata --- type 2 diabetes --- kidney damage --- inflammation --- apoptosis --- fibrosis --- Sargassum horneri --- (-)-loliolide --- fine dust --- HaCaT --- bilberry --- lingonberry --- polyphenols --- antioxidant compounds --- antimicrobial activity --- antimutagenicity --- altitude variations --- mitochondria --- neurodegeneration --- nutrient --- QM-ORSA --- antioxidative mechanisms --- reaction rate constants --- physiological conditions --- zebrafish embryo --- in vivo model --- antioxidant effect --- cudratrixanthone O --- reactive oxygen species --- nuclear transcription factor erythroid-2-like factor 2 --- hemeoxygenase-1

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Neurodegenerative diseases, including Alzheimer’s, Parkinson’s, Huntington’s, and amyotrophic lateral sclerosis, are the most common pathologies of the central nervous system currently without a cure. They share common molecular and cellular characteristics, including protein misfolding, mitochondrial dysfunction, glutamate toxicity, dysregulation of calcium homeostasis, oxidative stress, inflammation, and ageing, which contribute to neuronal death. Efforts to treat these diseases are often limited by their multifactorial etiology. Natural products, thanks to their multitarget activities, are considered promising alternatives for the treatment of neurodegeneration. This book deals with two different forms of natural products: extracts and isolated compounds. The study of the bioactivity of the extracts is extremely important as many studies have demonstrated the synergistic effect of the combination of different natural products. On the other hand, the investigation of the activity of specifically isolated natural products can be also important to understand their cellular and molecular mechanisms and to define the specific bioactive components in extracts or foods. This book can be considered an important contribution to knowledge of the neuroprotective effect of natural products and presents a great deal of information, related to both the benefits but also the limitations of their use in counteracting neurodegeneration.

Research & information: general --- Biology, life sciences --- Vitamin D --- Multiple Sclerosis --- symptom --- neurodegeneration --- oxidative injury --- Parkinson's disease --- terpenes, rotenone --- thymol --- Alzheimer's disease --- Centella asiatica --- hippocampus --- protein poshophatase 2 --- glycogen synthase kinase 3 --- B-cell lymphoma 2 --- neuroprotection --- nutraceuticals --- bioavailability --- stress response --- neurodegenerative disease --- bioactive compound --- natural extract --- β-amyloid peptide --- tau protein --- clinical trial --- human studies --- animal studies --- in vitro studies --- curcumin --- free radicals --- heme oxygenase --- safety profile --- type 2 diabetes --- inflammation --- vascular damage --- learning --- memory --- natural compound --- oxidative stress --- cognitive dysfunction --- cell death --- synapse loss --- protein aggregation --- neuroinflammation --- algae --- seaweeds --- neurodegenerative diseases --- auraptene --- dopamine neuron --- antioxidant --- mitochondria --- Chionanthus retusus --- flavonoid --- flower --- HO-1 --- NO --- Lippia citriodora --- VEE --- Vs --- relaxation --- depression --- cyclic AMP --- calcium --- blood-brain barrier --- catechin --- cognition --- epigallocatechin gallate --- green tea --- microbiota --- 5-(3,5-dihydroxyphenyl)-γ-valerolactone --- ascaroside pheromone --- C. elegans --- dauer --- neuronal signaling --- sexual behavior --- survival signals --- proteostasis --- chaperones --- autophagy --- ubiquitin-proteasome --- unfolded protein response --- natural compounds --- natural products --- ethics --- patients' autonomy --- beneficence --- nonmaleficence --- medical liability --- Parkinson's disease (PD) --- mitochondrial dysfunction --- dynamics --- hormesis --- ubiquitin‒proteasome system (UPS) --- mitophagy --- Vitamin D --- Multiple Sclerosis --- symptom --- neurodegeneration --- oxidative injury --- Parkinson's disease --- terpenes, rotenone --- thymol --- Alzheimer's disease --- Centella asiatica --- hippocampus --- protein poshophatase 2 --- glycogen synthase kinase 3 --- B-cell lymphoma 2 --- neuroprotection --- nutraceuticals --- bioavailability --- stress response --- neurodegenerative disease --- bioactive compound --- natural extract --- β-amyloid peptide --- tau protein --- clinical trial --- human studies --- animal studies --- in vitro studies --- curcumin --- free radicals --- heme oxygenase --- safety profile --- type 2 diabetes --- inflammation --- vascular damage --- learning --- memory --- natural compound --- oxidative stress --- cognitive dysfunction --- cell death --- synapse loss --- protein aggregation --- neuroinflammation --- algae --- seaweeds --- neurodegenerative diseases --- auraptene --- dopamine neuron --- antioxidant --- mitochondria --- Chionanthus retusus --- flavonoid --- flower --- HO-1 --- NO --- Lippia citriodora --- VEE --- Vs --- relaxation --- depression --- cyclic AMP --- calcium --- blood-brain barrier --- catechin --- cognition --- epigallocatechin gallate --- green tea --- microbiota --- 5-(3,5-dihydroxyphenyl)-γ-valerolactone --- ascaroside pheromone --- C. elegans --- dauer --- neuronal signaling --- sexual behavior --- survival signals --- proteostasis --- chaperones --- autophagy --- ubiquitin-proteasome --- unfolded protein response --- natural compounds --- natural products --- ethics --- patients' autonomy --- beneficence --- nonmaleficence --- medical liability --- Parkinson's disease (PD) --- mitochondrial dysfunction --- dynamics --- hormesis --- ubiquitin‒proteasome system (UPS) --- mitophagy