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Tea, made from the leaves of the Camellia senenisis plant, is the second most consumed beverage worldwide after water. Accumulating evidence from cellular, animal, epidemiological and clinical studies have linked tea consumption to various health benefits, such as chemoprevention of cancers, chronic inflammation, heart and liver diseases, diabetes, neurodegenerative diseases, etc. Although such health benefits have not been consistently observed in some intervention trials, positive results from clinical trials have provided direct evidence supporting the cancer-protective effect of green tea. In addition, numerous mechanisms of action have been suggested to contribute to tea’s disease-preventive effects. Furthermore, effects of the processing and storage of tea, as well as additives on tea’s properties have been investigated.
polyphenols --- n/a --- cell cycle arrest and apoptosis --- neuroblastoma --- salivary ?-amylase activity --- cancer apoptosis --- yaupon holly --- bioaccessibility --- fracture --- p53 --- tea --- Liubao tea --- BE(2)-C --- matrix metalloproteinase-1 (MMP-1) --- catechin --- renal stone --- oxalate --- protein expression --- 67LR --- Alzheimer’s disease --- EGCG --- nutraceutical --- diseases --- anti-oxidant --- heme oxygenase-1 --- polyphenol --- anxiety --- matcha --- ERCC1/XPF --- neuro-sphere --- tea consumption --- theanine --- Rosmarinic acid --- yerba mate --- hypercalciuria --- gene expression --- microbiota --- cohort study --- histone deacetylase 2 (HDAC2) --- guayusa --- nuclear factor erythroid 2-related factor 2 (Nrf2) --- DNA repair --- mRNA expression --- caffeine --- chemoprevention --- cisplatin --- 6-OH-11-O-hydroxyphenanthrene --- adrenal hypertrophy --- hepatic damage --- anti-photoaging --- cell death --- green tea --- kudingcha --- suberoylanilide hydroxamic acid (SAHA) --- epigallocatechin gallate (EGCG) --- stress-reduction --- calcium oxalate monohydrate --- Camellia sinensis --- chemoresistance --- tea polyphenols --- green tea polyphenols --- green tea catechins --- N-MYC --- cancer --- epigallocatechin-gallate (EGCG) --- Parkinson’s disease --- Alzheimer's disease --- Parkinson's disease
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Mens sana in corpore sano (a healthy mind in a healthy body) is a Latin phrase taken from Giovenale (Satire, X, 356) that remains relevant and is supported by today’s data regarding genetics and nutrition, and their contribution to mental health. The purpose of this Special Issue on “Nutrition and Fitness: Mental Health” is to provide an update on the latest evidence regarding the association between nutrition, physical activity (and inactivity) and physical fitness, and the mental health of children, adolescents, and adults. Particularly, papers (reviews and clinical or experimental studies) dealing with the association between nutrition, physical fitness, and mental health both in general and with regard to specific mental disorders, and nutrients and physical activity as agents for prevention, treatment, or augmentation of treatment for mental disorders, will be included.
Medicine --- depressive symptoms --- food insecurity --- nutrition --- adults --- generalized estimating equation --- review --- eating disorders --- physical activity --- problematic use of physical activity --- multiple sclerosis --- epigallocatechin gallate --- coconut oil --- interleukin-6 --- anxiety --- disability --- mental health --- emotional exhaustion --- cynicism --- professional efficacy --- sedentary behavior --- dietary behavior --- macronutrients --- energy intake --- motivation to diet --- motivation to exercise --- weight loss program --- obesity --- physical performance --- network analysis --- vitality --- psychiatry --- schizophrenia --- depression --- microbiota --- transplantation --- depressive symptoms --- food insecurity --- nutrition --- adults --- generalized estimating equation --- review --- eating disorders --- physical activity --- problematic use of physical activity --- multiple sclerosis --- epigallocatechin gallate --- coconut oil --- interleukin-6 --- anxiety --- disability --- mental health --- emotional exhaustion --- cynicism --- professional efficacy --- sedentary behavior --- dietary behavior --- macronutrients --- energy intake --- motivation to diet --- motivation to exercise --- weight loss program --- obesity --- physical performance --- network analysis --- vitality --- psychiatry --- schizophrenia --- depression --- microbiota --- transplantation
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Mens sana in corpore sano (a healthy mind in a healthy body) is a Latin phrase taken from Giovenale (Satire, X, 356) that remains relevant and is supported by today’s data regarding genetics and nutrition, and their contribution to mental health. The purpose of this Special Issue on “Nutrition and Fitness: Mental Health” is to provide an update on the latest evidence regarding the association between nutrition, physical activity (and inactivity) and physical fitness, and the mental health of children, adolescents, and adults. Particularly, papers (reviews and clinical or experimental studies) dealing with the association between nutrition, physical fitness, and mental health both in general and with regard to specific mental disorders, and nutrients and physical activity as agents for prevention, treatment, or augmentation of treatment for mental disorders, will be included.
Medicine --- depressive symptoms --- food insecurity --- nutrition --- adults --- generalized estimating equation --- review --- eating disorders --- physical activity --- problematic use of physical activity --- multiple sclerosis --- epigallocatechin gallate --- coconut oil --- interleukin-6 --- anxiety --- disability --- mental health --- emotional exhaustion --- cynicism --- professional efficacy --- sedentary behavior --- dietary behavior --- macronutrients --- energy intake --- motivation to diet --- motivation to exercise --- weight loss program --- obesity --- physical performance --- network analysis --- vitality --- psychiatry --- schizophrenia --- depression --- microbiota --- transplantation --- n/a
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Mens sana in corpore sano (a healthy mind in a healthy body) is a Latin phrase taken from Giovenale (Satire, X, 356) that remains relevant and is supported by today’s data regarding genetics and nutrition, and their contribution to mental health. The purpose of this Special Issue on “Nutrition and Fitness: Mental Health” is to provide an update on the latest evidence regarding the association between nutrition, physical activity (and inactivity) and physical fitness, and the mental health of children, adolescents, and adults. Particularly, papers (reviews and clinical or experimental studies) dealing with the association between nutrition, physical fitness, and mental health both in general and with regard to specific mental disorders, and nutrients and physical activity as agents for prevention, treatment, or augmentation of treatment for mental disorders, will be included.
depressive symptoms --- food insecurity --- nutrition --- adults --- generalized estimating equation --- review --- eating disorders --- physical activity --- problematic use of physical activity --- multiple sclerosis --- epigallocatechin gallate --- coconut oil --- interleukin-6 --- anxiety --- disability --- mental health --- emotional exhaustion --- cynicism --- professional efficacy --- sedentary behavior --- dietary behavior --- macronutrients --- energy intake --- motivation to diet --- motivation to exercise --- weight loss program --- obesity --- physical performance --- network analysis --- vitality --- psychiatry --- schizophrenia --- depression --- microbiota --- transplantation --- n/a
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Antioxidative polyphenols represented by tannins and flavonoids are rich in numerous food sources and traditional natural medicines and currently attracting increased attention in health care and food industries because of their multiple biological activities that are favorable to human health. Commemorating the outstanding achievements on tannins by Dr. Takuo Okuda on the occasion of his passing away in December 2016, his colleagues, friends, and worldwide experts of polyphenol research have contributed 18 papers on their recent study to the Special Issue of Molecules. This book is its reprinted form. This covers reviews of structural features, historical usages, and biological activities of unique class of ellagitannins and condensed tannins, and original articles on the most up-to-date findings on the anticancer effect of green tea catechins, the antivirus effect of tannins comparing with the clinically used drugs, the analytical method of ellagitannins using quantitative NMR, the chemical structures of Hydrangea-blue complex (pigment) and condensed tannins in Ephedra sinica and purple prairie clover, and the relationship of condensed tannins in legumes and grape-marc with methane production in the in vitro ruminant system, and others. This book will be useful to natural product chemists and also to researchers in pharmaceutical and/or food industry.
Coreopsis lanceolata L. --- UV-Vis --- methanogenesis --- Lythraceae --- flavanone --- grape marc --- TDDFT --- Ephedra sinica --- macrocyclic oligomer --- triple-negative breast cancer --- antioxidant --- purple prairie clover --- chalcone --- neuraminidase --- fatty acid synthase --- (?)-epigallocatechin gallate --- epidermal growth factor --- NMR spectroscopy --- Aluminum ion --- Onagraceae --- Hydrangea macrophylla --- synthetic analogues --- blue color development --- amyloid-? peptide --- FTIR --- oseltamivir carboxylate --- quantitative NMR --- phloroglucinolysis --- thin layer chromatography --- European historic leathers --- FASN inhibition --- ECD --- colorimetric tests --- taxanes --- cynandione A --- conservation method --- 5-O-caffeoylquinic acid --- ellagitannin --- PC12 --- condensed tannin --- Trapa taiwanensis Nakai --- 1H-NMR --- Acacia --- (?)-epigallocatechin 3-gallate --- Geranium thunbergii --- condensed tannins --- immunomodulatory effect --- Acacia mearnsii bark --- Escherichia coli --- oligomer --- Horner–Wadsworth–Emmons reaction --- lung tumor --- Aspergillus fumigates --- in vitro batch fermentation --- metal complex --- Myrtaceae --- Cynanchum auriculatum --- molecular interactions --- phenolic glycoside --- bamboo leaf extract --- stability --- Microsporum canis --- Cynanchum wilfordii --- thiolysis --- anti-inflammation --- hydrolysable tannin --- geraniin --- NGF --- polyphenol --- revision --- ESI-mass --- bioactivity --- antifungal activities --- interferon-? --- antitumor effect --- tannin composition --- oenothein B --- zanamivir --- 2-O-?-laminaribiosyl-4-hydroxyacetophenone --- anticancer activity --- proanthocyanidin --- vegetable tanning --- Dittrichia viscosa --- differentiation --- aurone --- antioxidants --- protein precipitation --- apoptosis --- polyphenolic FASN inhibitors --- forage legume --- biological activities --- ultrahigh-resolution negative mode MALDI-TOF mass spectrometry --- overlay method --- spectroscopy --- wattle tannin --- immune checkpoint --- hormesis --- 3-O-glucosyldelphinidin --- gallotannin --- proanthocyanidins --- fatty acids --- flavonol --- inhibition --- structure --- Candida spp. --- Malassezia spp. --- ORAC assay --- neuroprotection --- crystal structure --- tannins
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This book “Oxidative Stress Modulators and Functional Foods” is focused on the antioxidant role of natural products, involving their ability to modulate oxidative stress and/or reverse disease studied both in vitro and in animal models. Additionally, the molecular mechanisms of these actions and the modulation of signalling pathways related to inflammation, apoptosis, and survival response in the redox system by natural products are included.
Medicine --- Pharmaceutical industries --- high sugar-fat diet --- obesity --- β-adrenergic system --- cardiac dysfunction --- lycopene --- tomato-oleoresin --- coumarin --- pteryxin --- HO-1 --- Nrf2 --- oxidative stress --- Peucedanum japonicum Thunb --- RAW264.7 cells --- polysaccharide --- jujube pomace --- structural analysis --- antioxidant activity --- epigallocatechin-gallate --- liposomes --- diabetes mellitus --- antioxidant --- dendrimer --- electronic effect --- hydrogen atom transfer (HAT) --- single electron transfer-proton transfer (SET-PT) --- sequential proton loss electron transfer (SPLET) --- DPPH --- ultraviolet B --- gradient ethanol precipitation --- fucoidan --- HaCaT keratinocyte --- heme oxygenase-1 --- nutricosmetic --- folic acid --- nitric oxide --- neural tube defects --- NOR3 --- ESR --- LC/MS --- Benzo[a]pyrene --- myricetin --- BPDE-DNA adduct --- phase detoxifying enzyme --- Quamoclit angulata --- type 2 diabetes --- kidney damage --- inflammation --- apoptosis --- fibrosis --- Sargassum horneri --- (–)-loliolide --- fine dust --- HaCaT --- bilberry --- lingonberry --- polyphenols --- antioxidant compounds --- antimicrobial activity --- antimutagenicity --- altitude variations --- mitochondria --- neurodegeneration --- nutrient --- QM-ORSA --- antioxidative mechanisms --- reaction rate constants --- physiological conditions --- zebrafish embryo --- in vivo model --- antioxidant effect --- cudratrixanthone O --- reactive oxygen species --- nuclear transcription factor erythroid-2-like factor 2 --- hemeoxygenase-1 --- n/a --- (-)-loliolide
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This book “Oxidative Stress Modulators and Functional Foods” is focused on the antioxidant role of natural products, involving their ability to modulate oxidative stress and/or reverse disease studied both in vitro and in animal models. Additionally, the molecular mechanisms of these actions and the modulation of signalling pathways related to inflammation, apoptosis, and survival response in the redox system by natural products are included.
high sugar-fat diet --- obesity --- β-adrenergic system --- cardiac dysfunction --- lycopene --- tomato-oleoresin --- coumarin --- pteryxin --- HO-1 --- Nrf2 --- oxidative stress --- Peucedanum japonicum Thunb --- RAW264.7 cells --- polysaccharide --- jujube pomace --- structural analysis --- antioxidant activity --- epigallocatechin-gallate --- liposomes --- diabetes mellitus --- antioxidant --- dendrimer --- electronic effect --- hydrogen atom transfer (HAT) --- single electron transfer-proton transfer (SET-PT) --- sequential proton loss electron transfer (SPLET) --- DPPH --- ultraviolet B --- gradient ethanol precipitation --- fucoidan --- HaCaT keratinocyte --- heme oxygenase-1 --- nutricosmetic --- folic acid --- nitric oxide --- neural tube defects --- NOR3 --- ESR --- LC/MS --- Benzo[a]pyrene --- myricetin --- BPDE-DNA adduct --- phase detoxifying enzyme --- Quamoclit angulata --- type 2 diabetes --- kidney damage --- inflammation --- apoptosis --- fibrosis --- Sargassum horneri --- (–)-loliolide --- fine dust --- HaCaT --- bilberry --- lingonberry --- polyphenols --- antioxidant compounds --- antimicrobial activity --- antimutagenicity --- altitude variations --- mitochondria --- neurodegeneration --- nutrient --- QM-ORSA --- antioxidative mechanisms --- reaction rate constants --- physiological conditions --- zebrafish embryo --- in vivo model --- antioxidant effect --- cudratrixanthone O --- reactive oxygen species --- nuclear transcription factor erythroid-2-like factor 2 --- hemeoxygenase-1 --- n/a --- (-)-loliolide
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Dyslipidemia, and particularly hypercholesterolemia, remains a main cardiovascular disease risk factor, partly reversible with the improvement of life-style, including dietary, habits. Even when a pharmacological treatment is begun, dietary support to lipid-lowering is always desired. This book will provide a selection of new evidence on the possible lipid-lowering effects of some dietary and medicinal plant components, reporting some interesting reviews, experimental data and results from clinical trials. The book is adapted for experts in nutrition but also for all scientists involved in cardiovascular disease prevention.
beta-glucan --- fiber --- lipid profile --- cholesterol --- intestinal function --- green tea --- epigallocatechin gallate --- chitosan --- microspheres --- Eudragit --- metabolic diseases --- LCD score --- CHNS --- dyslipidemia --- dietary factor --- plant based --- animal based --- Chinese adults --- nutraceuticals --- PCSK9 --- SREBP --- HNF1α --- berberine --- metabolic syndrome --- plant extracts --- natural antioxidant --- polyphenols --- bergamot --- blackcurrant --- liver steatosis --- ovariectomized --- phytoestrogen --- vitamin B12 --- healthy --- Saudi Arabia --- serum cholesterol --- serum triglycerides --- serum low density lipoprotein --- serum high density lipoprotein --- dietary intake --- lifestyle --- black raspberry --- excessive choline --- TMAO --- hypercholesterolemia --- hepatic inflammation --- review --- CVD --- cardiovascular health --- dietary fats --- dietary fiber --- phytosterols --- plant-based diet --- dietary pattern --- sustainability --- propolis --- formononetin --- gastric ulcer --- rats --- Chrysanthemum morifolium Ramat leaves --- obesity --- lipidomics --- liquid chromatography tandem mass spectrometry --- phospholipid --- sphingolipid --- monacolins --- LDL-cholesterol --- red yeast rice --- clinical trial --- endothelial function --- alpha-linolenic acid --- flaxseed --- lipids --- omega-3 --- walnuts --- type 2 diabetes mellitus --- glibenclamide --- omega-3 fatty acids --- high fat diet --- transcription factors --- streptozotocin --- Armolipid Plus® --- nutraceutical --- supplementation --- blood pressure --- fasting plasma glucose --- n/a
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Phytotherapy is probably the oldest form of medicine; however, it represents a new therapeutic tool for healthcare workers. Indeed plants are an infinite source of novel molecules, with countless possible combinations. This collection of articles (a Special Issue from Molecules) brings together the most up-to-date studies on the use of plant-derived compounds, ranging from their anti-inflammatory, antioxidant, and anticancer effects to the revision of the prominent literature.
natural products --- phenylpropanoids --- phenolic acids --- plants --- depression --- behavioral disorders --- forced swim test --- tail suspension test --- anti-cancer activities --- multifloroside --- 10-oxyderivatives of oleoside secoiridoids --- structure-activity relationship --- flow cytometry --- epigallocatechin-3-gallate --- EGCG --- catechin --- green tea --- cancer preventive --- pharmacological activities --- Amelanchier alnifolia Nutt. --- carriers --- powders --- bioactive compounds --- functional food --- Ageratina havanensis --- flavonoids --- UPLC-ESI-MS/MS --- P-glycoprotein --- antioxidant potential --- nootkatone --- anti-inflammatory --- acute inflammation --- granuloma --- Pharbitis nil --- colorectal cancer --- KRAS --- muscle function --- juglone --- NLRP3 inflammasome --- caspase-1 --- IL-1β --- IL-18 --- plant secondary metabolites --- natural compounds --- biological activity --- phytochemistry --- pharmacological activity --- plant side effects --- Talisia esculenta --- Brosimum gaudichaudii --- Genipa americana --- Bromelia antiacantha --- RA-3 --- nephrotoxicity --- triterpene --- antioxidant --- hyperuricemia --- Hibiscus acetosella --- phenolic compound --- antibacterial --- UPLC --- Tabebuia impetiginosa --- Taheebo --- traditional uses --- immunopharmacology --- immunological disorders --- hesperidin --- new-clean process extraction --- nanocrystals --- anti-ageing --- zingerone --- lipopolysaccharide --- inflammation --- anti-oxidant --- cytokine storm --- procalcitonin --- histopathology --- doxorubicin --- Mahonia aquifolium --- matrix metalloproteinases --- cytotoxicity --- human lung adenocarcinoma --- n/a
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In this Special Issue, we have published papers on the health-promoting effects of nutraceuticals from different sources, and their effects in different pathologies. Extracts from plants have been analyzed, for example, extracts from olive leaves, Mikania micrantha, the devil’s claw, raspberries and others, alongside marine phytoplankton, egg-yolk and marketed dietary supplements. The effects of these extracts and dietary supplements have been studied in diseases associated with obesity, and in diseases where inflammation pathways are involved. The effectiveness of resveratrol and curcumin to support the anticancer activity of cisplatin has also been reported, as well as the ability of devil’s claw root extract to stimulate the CB2 receptors in synoviocytes in osteoarthritis patients. The anti-oxidant effect of marine phytoplankton has been studied on muscle damage, both in humans and in an animal model, and the effects of the metabolite of antocianin were analyzed in a mouse model of amyotrophic lateral sclerosis. Finally, reviews on the use of lactoferrin, ω3 and ω6 and abscisic acid have been reported, in addition to the crosstalk between prostate cancer and microbiota inflammation. Although it is not yet possible to draw definitive conclusions on the use of nutraceuticals, several mechanisms of action for many of them have been further clarified.
Humanities --- Social interaction --- fertility --- ingredients --- male reproduction --- semen parameters --- supplements --- allithiamine --- garlic --- hyperglycaemia --- advanced glycation end-products --- cytokines --- abscisic acid --- prediabetes --- type 2 diabetes mellitus --- metabolic syndrome --- insulin resistance --- adipocyte browning --- AMP-activated protein kinase --- food supplement --- frambinone --- meal frequency --- open-field test --- elevated plus maze --- sensory motor gating --- pre-pulse inhibition --- c-Fos --- amyotrophic lateral sclerosis --- anti-inflammatory --- antioxidant --- phenolic acid --- neuroprotective --- neurodegeneration --- obesity --- overweight --- beta-glucans --- chitosan --- follow up study --- weight loss programs --- weight gain --- weight loss --- body weight changes --- phytoplankton --- antioxidants --- muscle damage --- muscle recovery --- muscle soreness --- Viburnum opulus --- phenolic compounds --- adipogenesis --- PPARγ --- lipase inhibition --- green tea --- epigallocatechin --- lipid profile --- high-fat diet --- fast food --- osteoarthritis --- nutraceuticals --- polyphenols --- volatile compounds --- β-caryophyllene --- eugenol --- FAAH --- cannabinoid receptors --- phospholipases --- lactoferrin --- bovine milk --- nutraceutical --- human health --- resveratrol --- curcumin --- cisplatin --- head and neck cancer --- cell cycle --- apoptosis --- prostate cancer --- microbiota --- nutraceutical compounds --- fecundation --- inflammation --- cytokine --- growth factors --- metabolomics --- lipidomics --- ω-3PUFAs --- ω-6PUFAs --- endocannabinoids --- CRC --- fatty acids --- Gymnema inodorum --- gymnemic acid --- Mikania micrantha --- anti-hypercholesterolemia --- steatosis --- olive leaf --- macrophages --- fertility --- ingredients --- male reproduction --- semen parameters --- supplements --- allithiamine --- garlic --- hyperglycaemia --- advanced glycation end-products --- cytokines --- abscisic acid --- prediabetes --- type 2 diabetes mellitus --- metabolic syndrome --- insulin resistance --- adipocyte browning --- AMP-activated protein kinase --- food supplement --- frambinone --- meal frequency --- open-field test --- elevated plus maze --- sensory motor gating --- pre-pulse inhibition --- c-Fos --- amyotrophic lateral sclerosis --- anti-inflammatory --- antioxidant --- phenolic acid --- neuroprotective --- neurodegeneration --- obesity --- overweight --- beta-glucans --- chitosan --- follow up study --- weight loss programs --- weight gain --- weight loss --- body weight changes --- phytoplankton --- antioxidants --- muscle damage --- muscle recovery --- muscle soreness --- Viburnum opulus --- phenolic compounds --- adipogenesis --- PPARγ --- lipase inhibition --- green tea --- epigallocatechin --- lipid profile --- high-fat diet --- fast food --- osteoarthritis --- nutraceuticals --- polyphenols --- volatile compounds --- β-caryophyllene --- eugenol --- FAAH --- cannabinoid receptors --- phospholipases --- lactoferrin --- bovine milk --- nutraceutical --- human health --- resveratrol --- curcumin --- cisplatin --- head and neck cancer --- cell cycle --- apoptosis --- prostate cancer --- microbiota --- nutraceutical compounds --- fecundation --- inflammation --- cytokine --- growth factors --- metabolomics --- lipidomics --- ω-3PUFAs --- ω-6PUFAs --- endocannabinoids --- CRC --- fatty acids --- Gymnema inodorum --- gymnemic acid --- Mikania micrantha --- anti-hypercholesterolemia --- steatosis --- olive leaf --- macrophages
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