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1. Systeemoverzicht Common Rail systeem 
2. Brandstofopvoersysteem 
3. Hogedrukcomponenten van het Common Rail systeem 
4. Verstuivers 
5. Hogedrukverbingen 
6. Elektronische dieselregeling EDC


Common rail --- Dieselinspuitsystemen --- Elektronische dieselregeling EDC --- 629 --- 621.436 --- Common Rail (CR) systeem --- dieselmotoren --- common-rail-inspuiting --- verstuiver --- elektronische dieselcontrole --- dieselinspuiting; hogedruk (hogedrukinspuiting) --- 629 Transport vehicle engineering --- Transport vehicle engineering --- zuigerverbrandingsmotoren, dieselmotoren --- (zie ook: dieselinspuiting) --- (zie ook: dieselregeling) --- (zie ook: diesel-elektronica) --- (zie ook: edc) --- (zie ook: toerentalregeling; diesel) --- Motorcars engineering --- common rail --- auto's

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dieselmotoren --- dieselinspuitsystemen --- edc --- Common Rail --- 621.436 --- 629 --- Diesel motormanagementsystemen --- Diesellijninspuitpompen --- Dieselmotoren --- Radiaalplunjer verdelerpomp VR --- common-rail-inspuiting --- dieselinspuiting --- dieselinspuitpomp --- dieselinspuitpomp; pe --- dieselinspuitpomp; radiaalplunjerpomp --- dieselinspuitpomp; verdelerpomp --- dieselmotor --- elektronische dieselcontrole --- radiaalplunjerpomp --- verdelerpomp --- (zie ook: dieselinspuiting) --- (zie ook: diesel-elektronica) --- (zie ook: pomp) --- (zie ook: verdelerpomp) --- (zie ook: motor) --- (zie ook: dieselregeling) --- (zie ook: edc) --- (zie ook: toerentalregeling; diesel) --- (zie ook: plunjerpomp) --- (zie ook: dieselinspuitpomp; verdelerpomp) --- Motorcars engineering --- motormanagement

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Development provides an especially sensitive window whereby environmental contaminants can have significant and lasting effects on the morphology and function of many organs and systems. The importance of understanding developmental effects of environmental contaminants extends not only to developmental stages, but also to encompass the hypotheses of the developmental or fetal origins of adult disease. Such effects of environmental contaminants during development extend to health outcomes that can persist in adulthood, first become apparent in adulthood, or manifest in adulthood but only after a second hit/stressor. The diverse nature of possible environmental contaminants, ranging from persistent organic pollutants to emerging contaminants of concern, along with the diverse range of health implications, including autism, diabetes, cancer, infertility, and lower urinary tract function, make understanding developmental effects of environmental contaminants an ever growing and important field of study.This Special Issue aims to explore a variety of topics in line with the aims and scope of Toxics. Specifically, topics related to the developmental effects of environmental contaminants and/or their metabolites on the molecular, cellular, tissue, organ, organ system or organism, including mechanisms of toxicity, metabolism, risk assessment and management, as well as multiple stressor impacts in the context of aging or disease progression following developmental exposures.

Medicine --- Medical toxicology --- arsenic --- synaptic transmission --- long-term potentiation --- hippocampus --- development --- lower urinary tract --- bladder --- inflammation --- POPs --- developmental basis of adult disease --- multigenerational --- toxicants --- bronchopulmonary dysplasia --- therapeutics --- lung development --- selective serotonin reuptake inhibitor --- perinatal mortality --- neonatal morbidity --- fluoxetine --- sertraline --- endocrine-disrupting chemicals (EDC) --- Aroclor 1221 (A1221) --- PCBs --- vinclozolin --- social behavior --- sex differences --- transgenerational --- epigenetic --- endocrine-disrupting chemical (EDC) --- polychlorinated biphenyl (PCB) --- mating behavior --- paced mating --- ultrasonic vocalization (USV) --- estradiol --- triclosan --- triclocarbon --- detergents --- 4-nonylphenol --- Danio rerio --- zebrafish --- environmental toxicity --- aquatic environment --- ground water chemicals --- lower urinary tract dysfunction --- lower urinary tract symptoms --- BPH --- prostate --- axonal growth --- developmental neurotoxicity --- neuronal morphogenesis --- PBDE --- reactive oxygen species --- thyroid hormone --- pesticides --- prebiotic --- intestinal dysbiosis --- perigestational --- dysmetabolism --- risk factor --- behavior --- chemical screening --- literature comparison --- developmental toxicity --- negative control --- positive control --- rapid testing --- PFAS --- PFAS mixtures --- epigenetics --- microglia --- valproic acid --- primary motor cortex

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Canada's engagement with post-independence Africa presents a puzzle. Although Canada is recognized for its activism where Africa is concerned, critics have long noted the contradictions that underlie Canadian involvement. Focusing on the period following 2000, and by juxtaposing Jean Chrétien's G8 activism with the Harper government's retreat from continental engagement, David R. Black's Canada and Africa in the New Millennium illustrates a history of consistent inconsistency in Canada's relationship with Africa. Black combines three interpretive frames to account for this record: the tradition of "good international citizenship"; Canada's role as a benign face of Western hegemonic interests in Africa; and Africa's role as the basis for a longstanding narrative concerning Canada's ethical mission in the world. To examine Africa's place in Canada's foreign policy-and Canada's place in Africa-Black focuses on G8 diplomacy, foreign aid, security assistance through peace operations and training, and the increasingly controversial impact of Canadian extractive companies. Offering an integrated account of Canada's role in sub-Saharan Africa, Black provides a way of understanding the nature and resilience of recent shifts in Canadian policy. He underscores how Africa-though marginal to Canadian interests as traditionally conceived-has served as an important marker of Canada's international role.

Canada --- Africa --- Eastern Hemisphere --- Canada (Province) --- Canadae --- Ceanada --- Chanada --- Chanadey --- Dominio del Canadá --- Dominion of Canada --- Jianada --- Kʻaenada --- Kanada (Dominion) --- Ḳanadah --- Kanadaja --- Kanadas --- Ḳanade --- Kanado --- Kanakā --- Province of Canada --- Republica de Canadá --- Yn Chanadey --- Καναδάς --- Канада --- קאנאדע --- קנדה --- كندا --- کانادا --- カナダ --- 加拿大 --- 캐나다 --- Lower Canada --- Upper Canada --- Foreign relations --- Politics and government --- Kaineḍā --- Africa and the West. --- CIDA. --- Canadian mining companies. --- DFAIT. --- EDC. --- Lloyd Axworthy. --- NEPAD. --- corporate social responsibility. --- development assistance. --- hegemony. --- human security. --- moral identity. --- multilateralism. --- non-governmental development organizations. --- norm entrepreneurship. --- peacekeeping. --- the Africa Action Plan. --- the Canadian Forces. --- the Commonwealth.

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The concept of advanced therapy medicinal products (ATMPs) encompasses novel kinds of medicines for human use that are based on genes, cells or tissues. These intend to offer not only regeneration, but complete functional recovery of diseased tissues and organs using different strategies. Gene therapy, cell therapy and tissue engineering are the main areas in which promising advanced therapies are emerging. The eye is a very complex organ whose main structures, the cornea and the retina, play a pivotal role in maintaining normal vision, as severe alterations in these tissues can lead to blindness. Ocular tissues are starting to benefit from ATMPs by fighting against the enormous complexity and devastating potential of many ocular diseases. However, developments arising from this field of work face important challenges related to vectors to deliver drugs and genetic material to target tissues, suitable biomaterials to prepare cell scaffolds and cell stemness, among others—not to mention the complicated legislation around ATMPs, the complexity in production and quality control and the absence of standardized protocols.The purpose of this Special Issue is to serve as an overview of the current progress in the application of cell and gene therapies, as well as tissue engineering to restore functionality in diseased ocular structures, and the challenges linked to reaching patients.

Medicine --- MPC polymer --- dry eye --- ocular surface --- lacrimal fluid --- mucin --- 3D bioprinting --- cornea --- retina --- ophthalmology --- tissue regeneration --- electrospinning --- conjunctiva --- decellularized tissue matrix --- small intestinal submucosa --- urinary bladder matrix --- polycaprolactone --- fiber --- tissue engineering --- stratification --- conjunctival epithelial cells --- hydrogel --- keratoplasty --- scaffold --- collagen --- advanced therapy medicinal product --- ATMP --- cell therapy --- gene therapy --- eye --- ocular --- regulatory --- marketing authorization --- double-crosslinking --- carbodiimide --- glutaraldehyde --- sodium metabisulfite --- sodium borohydride --- EDC/NHS --- stem cells --- retinal diseases --- optic nerve diseases --- cell replacement --- cell sources --- advanced therapies --- ocular mucosa --- blindness --- CLET --- limbal niche --- limbal stem cell --- LSCD --- mesenchymal stem cell transplantation --- MSCT --- corneal limbus --- decellularized xenograft --- recellularization --- mesenchymal stem cells --- MPC polymer --- dry eye --- ocular surface --- lacrimal fluid --- mucin --- 3D bioprinting --- cornea --- retina --- ophthalmology --- tissue regeneration --- electrospinning --- conjunctiva --- decellularized tissue matrix --- small intestinal submucosa --- urinary bladder matrix --- polycaprolactone --- fiber --- tissue engineering --- stratification --- conjunctival epithelial cells --- hydrogel --- keratoplasty --- scaffold --- collagen --- advanced therapy medicinal product --- ATMP --- cell therapy --- gene therapy --- eye --- ocular --- regulatory --- marketing authorization --- double-crosslinking --- carbodiimide --- glutaraldehyde --- sodium metabisulfite --- sodium borohydride --- EDC/NHS --- stem cells --- retinal diseases --- optic nerve diseases --- cell replacement --- cell sources --- advanced therapies --- ocular mucosa --- blindness --- CLET --- limbal niche --- limbal stem cell --- LSCD --- mesenchymal stem cell transplantation --- MSCT --- corneal limbus --- decellularized xenograft --- recellularization --- mesenchymal stem cells