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This detailed background review paper provides a summary of the relevant literature (up to September 2001) relevant to the standardisation and validation of the rodent uterotrophic bioassay. The rodent uterotrophic bioassay is being validated as part of the OECD Test Guidelines Programme.  The rodent uterotrophic bioassay is based on the principle that the uterus is under the control of oestrogens to stimulate and maintain growth. If endogenous sources of this hormone are not available, the animal will require an exogenous source to initiate and/or restore uterine growth.  

Environment --- Balance of nature --- Biology --- Bionomics --- Ecological processes --- Ecological science --- Ecological sciences --- Environmental biology --- Oecology --- Environmental sciences --- Population biology --- Ecology

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This Test Guideline is designed to assess the effects of prolonged exposure to chemicals on the growth of juvenile fish. Juvenile fish in exponential growth phase are placed, after being weighed, in test chambers and are normally exposed to five sublethal concentrations of the test substance dissolved in water preferably under flowthrough, or, if not possible, under appropriate semi static (static-renewal) conditions. The test duration is 28 days. The daily food ration is based on initial fish weights and may be recalculated after 14 days. The study report should include the concentration measurement of the test substance, the observation of external abnormalities and abnormal behavior and the fish weighting at the end of the test. Effects on growth rates are analyzed using a regression model in order to estimate the concentration that would cause a x % variation in growth rate, i.e. ECx. Alternatively, the data may be compared with control values in order to determine the lowest observed effect concentration (LOEC) and the no observed effect concentration (NOEC).

Ecology --- Balance of nature --- Biology --- Bionomics --- Ecological processes --- Ecological science --- Ecological sciences --- Environment --- Environmental biology --- Oecology --- Environmental sciences --- Population biology

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General ecology and biosociology --- Ecology --- -Balance of nature --- Biology --- Bionomics --- Ecological processes --- Ecological science --- Ecological sciences --- Environment --- Environmental biology --- Oecology --- Environmental sciences --- Population biology --- Philosophy --- Philosophy. --- -Philosophy --- Ecophilosophy

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General ecology and biosociology --- Ecology --- Tropical climate --- Tropical climate. --- Balance of nature --- Biology --- Bionomics --- Ecological processes --- Ecological science --- Ecological sciences --- Environment --- Environmental biology --- Oecology --- Environmental sciences --- Population biology

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""The force that through the green fuse drives the flower / Drives my green age; that blasts the roots of trees / Is my destroyer," wrote poet Dylan Thomas. In this evocative book a widely respected ecological scientist and activist draws on the poet's image and his own environmental research to demonstrate the intricate interconnections among disparate ecosystems. He takes us from the salmon runs of southwestern Alaska and the marshes of the Florida everglades to the coral reefs of the South Pacific and the depopulated bleakness of the Tibetan plateau. The result is that rare book that bridges the cultures of science and art. Lyrical and vivid portraits of natural wonders and the threats to them are combined with precise scientific accounts of natural processes and their disturbances. The Green Fuse will show nonscientists the fascination of ecological detective work and renew scientists' love for the beauty of the world under their microscopes." "Written from personal passion as well as intellectual analysis, Harte's stories illuminate, without sermonizing, the damage to natural systems brought about by technological hubris and calculated political ruthlessness. To fuse is to join together; "the green fuse" symbolizes the basic unity behind natural diversity. But Harte observes that a green fuse may also be the weak link in an overloaded system or the slow burning wick on an ecological bomb. The scientist's words echo the poet's insight: as The Green Fuse reminds us, the energies that created human liberation from nature can also be those that bring about the human destruction of nature."--Jacket.

Ecology. --- Ecology --- Earth & Environmental Sciences --- Balance of nature --- Biology--Ecology --- Bionomics --- Ecological processes --- Ecological science --- Ecological sciences --- Ecologie --- Environment --- Environmental biology --- Environnement --- Oecology --- Biology --- Environmental sciences --- Population biology