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This book reports cutting-edge technology in nanoprobes or nanobiomaterials used for the accurate diagnosis and therapy of tumors, involving a multidisciplinary of chemistry, materials science, oncology, biology, and medicine.

Technology: general issues --- Chemical engineering --- aptamers --- nanomaterials --- cancer --- treatment --- targeting --- NIR-II fluorescent probes --- activatable strategy --- NIR-II fluorescence imaging --- biomarker --- biosensing --- ferritin --- drug delivery --- thermally induced drug loading --- computational analysis --- iron oxide nanoparticles --- magnetotheranostics --- aggregation-induced emission --- NIR-II emission --- phototheranostics --- cancer treatment --- dendrimers --- gold nanoparticles --- CpG-ODN --- immunotherapy --- T cells --- ion interference therapy --- ions --- inorganic nanoparticles --- SERS --- Raman --- microbeads --- multiplex --- immunoassays --- circulating tumor cells --- ovarian cancer --- folic acid --- fluorescent-magnetic nanoparticles --- isolation --- identification --- living sample viability measurement --- atomic force microscopy --- AFM oscillating sensor method --- nanomotion --- n/a

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Creating antibacterial surfaces is the primary approach in preventing the occurrence and diffusion of clinical infections and foodborne diseases as well as in contrasting the propagation of pandemics in everyday life. Proper surface engineering can inhibit microorganism spread and biofilm formation, can contrast antimicrobial resistance (AMR), and can avoid cross-contamination from a contaminated surface to another and eventually to humans. For these reasons, antibacterial surfaces play a key role in many applications, ranging from biomedicine to food and beverage materials, textiles, and objects with frequent human contact. The incorporation of antimicrobial agents within a surface or their addition onto a surface are very effective strategies to achieve this aim and to properly modify many other surface properties at the same time. In this framework, this Special Issue collects research studying several materials and methods related to the antibacterial properties of surfaces for different applications and discussions about the environmental and human-safety aspects.

Technology: general issues --- nanocomposite --- mechanical properties --- cytotoxicity --- nanosilica --- antibiotics --- drug loading --- electrodeposition --- halloysite nanotubes --- zinc --- metal nanoparticles --- titanium implants --- cellulose --- silver --- nanoparticle --- antibacterial --- composite --- thin film --- xanthan gum --- zinc oxide --- quorum sensing --- biofilm --- virulence --- S. marcescens --- C. violaceum --- proteins --- titanium dioxide --- functionalization --- hybrid composites --- antimicrobial coatings --- aluminum-doped zinc oxide (AZO) --- RF sputtering (RFS) --- supersonic cluster beam deposition (SCBD) --- silver nanoparticles --- atomic force microscopy (AFM) --- health --- biomedical applications --- food packaging --- antibacterial coating --- antimicrobial peptide --- plasma polymer --- LL 37 --- Magainin --- Parasin --- bacterial attachment --- polylactide --- photodynamic --- supramolecular systems --- micelles --- drug delivery --- copolymers --- ring opening polymerization --- aPDT --- BODIPY --- antimicrobial --- polycaprolactone (PCL) --- nanofibers --- electrospinning --- sputtering --- antiviral --- biomedical --- bioremediation --- antifouling --- metal ions --- graphene --- antibiotic resistance --- foams --- biomaterials

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This book aims to summarize the latest achievements in the development and manufacturing of modern biomaterials used in modern medicine and dentistry, for example, in cases where, as a result of a traffic or sports accident, aging, resection of organs after oncological surgery, or dangerous inflammation, there is a need to replace lost organs, tissues, and parts of the human body. The essence of biomedical materials is their constant contact with living tissues, organisms, or microorganisms and, therefore, they should meet numerous requirements from various fields, including medicine, biology, chemistry, tissue engineering, and materials science. For this reason, biomaterials must be compatible with the organism, and biocompatibility issues must be addressed before using the product in a clinical setting. The production and synthesis of biomaterials require the use of various technologies and methods to obtain the appropriate material, which is then processed using advanced material processing technologies. Often, however, it is necessary to directly manufacture a specific product with individualized geometric features and properties tailored to the requirements of a particular patient. In such cases, additive manufacturing methods are increasingly used. In this sense, it can be considered that the Biomaterials 4.0 stage has been reached, and detailed information is included in the individual chapters of this book on the achievements in the development and manufacturing of modern biomaterials used in modern regenerative medicine, regenerative dentistry, and tissue engineering.

Technology: general issues --- sol-gel phase transitions --- injectable scaffolds --- chitosan --- calcium β-glycerophosphate --- rheology --- bone tissue engineering --- diblock copolymers --- drug delivery systems --- nanoparticles --- nanoprecipitation --- self-assembly --- implant --- stainless steel --- nickel --- leaching --- nitrogen --- cytotoxicity --- nanodendrites --- nanostar --- fibroblast cells --- gelatin --- one-pot synthesis --- hollow mesoporous silica --- porous silica --- high drug loading capacity --- drug delivery system --- fretting --- fretting wear --- Ni-Cr-Mo --- dental alloys --- titaniumcarbonitride --- Ti(C, N) coating --- thin films --- zirconium carbide --- antimicrobial properties --- medical implants --- 316L stainless steel --- sintering --- surface nitriding --- nitrogen absorption --- response surface methodology --- sodium alginate --- hydrogel material --- regenerative medicine --- urethra --- hybrid materials --- hydroxyapatite --- FEA --- V-shaped tooth defects --- fillings --- glass-ionomer cement --- flowable composite --- stomatognathic system --- prosthetic restorations --- surgical guide --- dental prosthesis restoration manufacturing center --- CBCT tomography --- dental implants --- implant-scaffolds --- hybrid multilayer biological-engineering composites biomaterials --- CAD/CAM methods --- additive manufacturing technologies --- selective laser sintering --- stereolithography --- Dentistry 4.0 --- Industry 4.0 --- robocasting --- bioactive glass --- scaffold --- sol–gel --- 45S5 Bioglass® --- biomaterials --- biomedical implants --- additive manufacturing --- dental prosthetic restorations --- Ti6Al4V dental alloy --- structural X-ray analysis --- energy-dispersive X-ray spectroscope --- metallography --- tensile and bending strength --- corrosion resistance --- tribological tests --- in-vitro tests --- industry 4.0 --- dentistry 4.0 --- SARS-CoV-2 pandemic --- SPEC strategy --- elimination clinical aerosol at the source --- dendrological matrix --- photopolymer materials --- additive digital light printing --- dentistry sustainable development --- dental prophylaxis --- dental interventionistic treatment --- caries --- periodontology --- toothlessness --- endodontics --- dental implantology --- dental prosthetics --- dentist safety --- dentist ethics --- Co–Cr dental alloys --- corrosion --- porcelain firing --- SLM --- MSM --- CST --- light-cured composites --- photopolymerization process --- microhardness --- optimization --- regression analysis --- health --- well-being --- long and healthy life policy --- medicine --- dentistry --- medical ethics --- COVID-19 pandemic --- bioengineering --- medical engineering --- dental engineering --- biomedical materials --- Bioengineering 4.0 --- engineers’ ethics --- filling materials --- sealants --- obturation --- gutta-percha --- Resilon --- procedural benchmarking --- comparative matrices --- virtual approach --- digital twin --- scanning electron microscopy --- n/a --- sol-gel --- Co-Cr dental alloys --- engineers' ethics --- Waddawalla / Well 40 (Great Sandy Desert WA SF51-08)

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This book aims to summarize the latest achievements in the development and manufacturing of modern biomaterials used in modern medicine and dentistry, for example, in cases where, as a result of a traffic or sports accident, aging, resection of organs after oncological surgery, or dangerous inflammation, there is a need to replace lost organs, tissues, and parts of the human body. The essence of biomedical materials is their constant contact with living tissues, organisms, or microorganisms and, therefore, they should meet numerous requirements from various fields, including medicine, biology, chemistry, tissue engineering, and materials science. For this reason, biomaterials must be compatible with the organism, and biocompatibility issues must be addressed before using the product in a clinical setting. The production and synthesis of biomaterials require the use of various technologies and methods to obtain the appropriate material, which is then processed using advanced material processing technologies. Often, however, it is necessary to directly manufacture a specific product with individualized geometric features and properties tailored to the requirements of a particular patient. In such cases, additive manufacturing methods are increasingly used. In this sense, it can be considered that the Biomaterials 4.0 stage has been reached, and detailed information is included in the individual chapters of this book on the achievements in the development and manufacturing of modern biomaterials used in modern regenerative medicine, regenerative dentistry, and tissue engineering.

Technology: general issues --- sol-gel phase transitions --- injectable scaffolds --- chitosan --- calcium β-glycerophosphate --- rheology --- bone tissue engineering --- diblock copolymers --- drug delivery systems --- nanoparticles --- nanoprecipitation --- self-assembly --- implant --- stainless steel --- nickel --- leaching --- nitrogen --- cytotoxicity --- nanodendrites --- nanostar --- fibroblast cells --- gelatin --- one-pot synthesis --- hollow mesoporous silica --- porous silica --- high drug loading capacity --- drug delivery system --- fretting --- fretting wear --- Ni-Cr-Mo --- dental alloys --- titaniumcarbonitride --- Ti(C, N) coating --- thin films --- zirconium carbide --- antimicrobial properties --- medical implants --- 316L stainless steel --- sintering --- surface nitriding --- nitrogen absorption --- response surface methodology --- sodium alginate --- hydrogel material --- regenerative medicine --- urethra --- hybrid materials --- hydroxyapatite --- FEA --- V-shaped tooth defects --- fillings --- glass-ionomer cement --- flowable composite --- stomatognathic system --- prosthetic restorations --- surgical guide --- dental prosthesis restoration manufacturing center --- CBCT tomography --- dental implants --- implant-scaffolds --- hybrid multilayer biological-engineering composites biomaterials --- CAD/CAM methods --- additive manufacturing technologies --- selective laser sintering --- stereolithography --- Dentistry 4.0 --- Industry 4.0 --- robocasting --- bioactive glass --- scaffold --- sol-gel --- 45S5 Bioglass® --- biomaterials --- biomedical implants --- additive manufacturing --- dental prosthetic restorations --- Ti6Al4V dental alloy --- structural X-ray analysis --- energy-dispersive X-ray spectroscope --- metallography --- tensile and bending strength --- corrosion resistance --- tribological tests --- in-vitro tests --- industry 4.0 --- dentistry 4.0 --- SARS-CoV-2 pandemic --- SPEC strategy --- elimination clinical aerosol at the source --- dendrological matrix --- photopolymer materials --- additive digital light printing --- dentistry sustainable development --- dental prophylaxis --- dental interventionistic treatment --- caries --- periodontology --- toothlessness --- endodontics --- dental implantology --- dental prosthetics --- dentist safety --- dentist ethics --- Co-Cr dental alloys --- corrosion --- porcelain firing --- SLM --- MSM --- CST --- light-cured composites --- photopolymerization process --- microhardness --- optimization --- regression analysis --- health --- well-being --- long and healthy life policy --- medicine --- dentistry --- medical ethics --- COVID-19 pandemic --- bioengineering --- medical engineering --- dental engineering --- biomedical materials --- Bioengineering 4.0 --- engineers' ethics --- filling materials --- sealants --- obturation --- gutta-percha --- Resilon --- procedural benchmarking --- comparative matrices --- virtual approach --- digital twin --- scanning electron microscopy --- Waddawalla / Well 40 (Great Sandy Desert WA SF51-08)