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Dog. --- Firing. --- Position. --- Tail docking.
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Behavioral consequences. --- Education. --- Medical consequences. --- Tail docking.
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Pig. --- Pigs. --- Tail docking. --- Tail-biting. --- Welfare.
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Castration. --- Lamb. --- Lambs. --- Method. --- Old. --- Pain. --- Reduction. --- Response. --- Tail docking.
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The definitive reference for space engineers on rendezvous and docking/berthing (RVD/B) related issues, this book answers key questions such as: How does the docking vehicle accurately approach the target spacecraft? What technology is needed aboard the spacecraft to perform automatic rendezvous and docking, and what systems are required by ground control to supervise this process? How can the proper functioning of all rendezvous-related equipment, systems and operations be verified before launch? The book provides an overview of the major issues governing approach and mating strategies, and system concepts for rendezvous and docking/berthing. These issues are described and explained such that aerospace engineers, students and even newcomers to the field can acquire a basic understanding of RVD/B. The author would like to extend his thanks to Dr Shufan Wu, GNC specialist and translator of the book's Chinese edition, for his help in the compilation of these important errata.
Orbital rendezvous (Space flight) --- Space vehicles --- 629.78 --- Docking of space vehicles --- Space vehicle docking --- Aerospace engineering --- Space rockets --- Spacecraft --- Spaceships --- Astronautics --- Navigation (Astronautics) --- Rocketry --- Vehicles --- Rendezvous, Orbital --- Rendezvous (Space) --- Rendezvous in space --- Space orbital rendezvous --- Space flight --- Space ships --- Space stations --- Automatic control --- Docking --- Ruimteschip --- Piloting --- Orbital rendezvous (Space flight). --- Mechanical Engineering --- Engineering & Applied Sciences --- Aeronautics Engineering & Astronautics --- Automatic control. --- Docking.
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Anxiety. --- Blood sampling. --- Castrating. --- Lamb. --- Lambs. --- Method. --- Pain. --- Tail docking. --- Welfare.
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Drug repositioning is the process of identifying new indications for existing drugs. At present, the conventional de novo drug discovery process requires an average of about 14 years and US$2.5 billion to approve and launch a drug. Drug repositioning can reduce the time and cost of this process because it takes advantage of drugs already in clinical use for other indications or drugs that have cleared phase I safety trials but have failed to show efficacy in the intended diseases. Historically, drug repositioning has been realized through serendipitous clinical observations or improved understanding of disease mechanisms. However, recent technological advances have enabled a more systematic approach to drug repositioning. This eBook collects 16 articles from 112 authors, providing readers with current advances and future perspectives of drug repositioning.
database --- Integrative strategies --- molecular docking --- polypharmacology --- multi-omics --- computational analysis --- Drug Repositioning --- data sharing --- Patenting
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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact
chemoinformatics --- drug design --- Molecular modeling --- Computational Chemistry --- QSAR --- molecular docking --- QSPR --- Virtual Screening --- molecular dynamics
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Drug repositioning is the process of identifying new indications for existing drugs. At present, the conventional de novo drug discovery process requires an average of about 14 years and US$2.5 billion to approve and launch a drug. Drug repositioning can reduce the time and cost of this process because it takes advantage of drugs already in clinical use for other indications or drugs that have cleared phase I safety trials but have failed to show efficacy in the intended diseases. Historically, drug repositioning has been realized through serendipitous clinical observations or improved understanding of disease mechanisms. However, recent technological advances have enabled a more systematic approach to drug repositioning. This eBook collects 16 articles from 112 authors, providing readers with current advances and future perspectives of drug repositioning.
database --- Integrative strategies --- molecular docking --- polypharmacology --- multi-omics --- computational analysis --- Drug Repositioning --- data sharing --- Patenting
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This thesis work is focusing on the design and analysis of a Floating Dry Dock complying with DNV-GL Rules with emphasis on the structural design and stability. The mentioned work was carried out during the internship in Nelton Sp. z o.o. located in Szczecin from July 3 till November 8 in the year 2017. Floating Dry Docks are being widely used for the construction of ships, docking of ships for inspection and repairs and also for ship launching. One of the major advantage of floating dry docks from the graving docks is mobility. And a floating dry dock doesn’t require any yard space. Floating dry docks are built to different lifting capacities, and there are different types of designs available as well based on the requirements. With the requirement for a pontoon type floating dry dock with 5 modules of pontoons and 2 dock wings which can be dismantled, the design is carried out for the same with an appropriate connection between the pontoons and the wing tanks. Just like any other structure, the safety is of prime concern and hence various classification societies developed rules for the design of floating dry docks with regard to the structural design, stability, machinery, other safety and protection systems and survey requirements. Current work is based on the rules developed by DNV-GL. With a stability check based on approximated weights available, the work carried out involves the global structural design, with adequate connections between different modules. With structural design in place, more or less actual weights of the structure is calculated and then the stability check is done based on that. Based on a feasibility check, the capacity and dimensions of this floating dry dock is found suitable for the construction of all the types of submarines which are currently under consideration by the Polish Navy.
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