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Virtual reality (VR) and augmented reality (AR) have long histories in the healthcare sector, offering the opportunity to develop a wide range of tools and applications aimed at improving the quality of care and efficiency of services for professionals and patients alike. The best-known examples of VR–AR applications in the healthcare domain include surgical planning and medical training by means of simulation technologies. Techniques used in surgical simulation have also been applied to cognitive and motor rehabilitation, pain management, and patient and professional education. Serious games are ones in which the main goal is not entertainment, but a crucial purpose, ranging from the acquisition of knowledge to interactive training.These games are attracting growing attention in healthcare because of their several benefits: motivation, interactivity, adaptation to user competence level, flexibility in time, repeatability, and continuous feedback. Recently, healthcare has also become one of the biggest adopters of mixed reality (MR), which merges real and virtual content to generate novel environments, where physical and digital objects not only coexist, but are also capable of interacting with each other in real time, encompassing both VR and AR applications.This Special Issue aims to gather and publish original scientific contributions exploring opportunities and addressing challenges in both the theoretical and applied aspects of VR–AR and MR applications in healthcare.

reaction time --- accuracy rate --- serious game --- PC-based game --- MCI --- dementia --- elderly healthcare --- cognitive function --- surgical simulation --- augmented reality --- spine surgery --- hybrid simulator --- pedicle screws fixation training --- unity game engine --- healthcare simulation --- mixed reality --- hybrid --- medical training --- serious games --- rehabilitation --- elderly --- body tracking --- exercise games --- AMD --- salience --- virtual reality --- VR --- preventive care --- self-regulation --- assisted Neurofeedback --- neurostimulation --- mindfulness --- randomized --- serious games BCI --- exergames --- personalized exergames --- multicomponent training --- wearable sensors --- older adults --- game design --- interaction design --- mild cognitive impairment --- machine learning --- feature selection --- data transformations --- classification --- n/a

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Some in the social sciences argue that the same logic applies to both qualitative and quantitative methods. In A Tale of Two Cultures, Gary Goertz and James Mahoney demonstrate that these two paradigms constitute different cultures, each internally coherent yet marked by contrasting norms, practices, and toolkits. They identify and discuss major differences between these two traditions that touch nearly every aspect of social science research, including design, goals, causal effects and models, concepts and measurement, data analysis, and case selection. Although focused on the differences between qualitative and quantitative research, Goertz and Mahoney also seek to promote toleration, exchange, and learning by enabling scholars to think beyond their own culture and see an alternative scientific worldview. This book is written in an easily accessible style and features a host of real-world examples to illustrate methodological points.

Social sciences --- Political sociology --- Political science --- Mass political behavior --- Political behavior --- Sociology --- Administration --- Civil government --- Commonwealth, The --- Government --- Political theory --- Political thought --- Politics --- Science, Political --- State, The --- Research --- Methodology. --- Sociological aspects --- 2 x 2 tables. --- David Hume. --- Fundamental Principle of Variable Transformation. --- Fundamental Problem of Causal Inference. --- Fundamental Tradeoffs. --- Hooke's law. --- Principle of Conceptual Opposites. --- Principle of Conceptual Overlap. --- Principle of Unimportant Variation. --- additive-linear causal model. --- aggregation technique. --- asymmetry. --- case selection. --- case studies. --- cases. --- categories. --- causal complexity. --- causal effects. --- causal heterogeneity. --- causal inference. --- causal mechanism. --- causal model. --- causal models. --- causal-process observations. --- causality. --- causation. --- cause. --- causes-of-effects approach. --- characteristics. --- concepts. --- conceptualization. --- constant conjunction definition. --- control variables. --- counterfactual analysis. --- counterfactual definition. --- counterfactuals. --- cross-case analysis. --- data analysis. --- data transformations. --- data-set observations. --- definitions. --- dependent variable. --- effects-of-causes approach. --- empirical testing. --- equifinality. --- error. --- experiments. --- fuzziness. --- fuzzy-set analysis. --- fuzzy-set transformations. --- generalization. --- hypothesis testing. --- indicators. --- individual case analysis. --- individual cases. --- inferential statistics. --- logging. --- logic. --- meaning retention. --- measurement. --- membership functions. --- methodological pluralism. --- minimum rewrite rule. --- mixed-method research. --- multimethod research. --- multiple causation. --- natural language. --- necessary condition. --- nonoccurrence. --- occurrence. --- opposites. --- perfect predictors. --- political science. --- probability theory. --- process tracing. --- qualitative research. --- quantitative research. --- regression. --- scale types. --- scope conditions. --- semantic transformations. --- semantics. --- set theory. --- set-theoretic causal model. --- set-theoretic generalization. --- social science research. --- social sciences. --- sociology. --- standardization. --- static causal asymmetry. --- statistical analysis. --- statistical method. --- statistical model. --- statistics. --- sufficient condition. --- symmetry. --- translation problems. --- typologies. --- variable transformations. --- within-case analysis. --- within-model responses.