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Bacterial nanocellulose (BNC), cellulose nanocrystals (CNCs), and cellulose nanofibers (CNFs) are three nanometric forms of the most abundant natural polymer (viz. cellulose), and are currently under the spotlight in numerous fields of modern science and technology. The eco-friendly connotations, peculiar features, and multiple functionalities of these nanoscale cellulosic substrates are being explored to engineer advanced nanocomposites and nanohybrid materials for application in manifold domains, such as mechanics, optics, electronics, energy, environment, biology, and medicine.The aim of this Special Issue titled “Advanced Nanocellulose-Based Materials: Production, Properties, and Applications” is to gather original research and review contributions from the world-leading scientists working with nanocellulose. Thus, research that is representative of the current developments dealing with the production methodologies, properties, and applications of nanocellulose-based materials (e.g., nanocomposites, hybrids, aerogels, hydrogels, films, and fibers) are presented in the Special Issue.
Technology: general issues --- bacterial nanocellulose --- lignosulfonates --- mechanical performance --- thermal-oxidative stability --- ion-exchange membranes --- biobased separators --- ionic conductivity --- oxidized bacterial cellulose --- chitosan --- alginate --- layer-by-layer assembly --- multi-layered patches --- dexpanthenol --- wound healing --- cellulose nanocomposite --- ice-templating --- interface --- orientation --- mechanical properties --- cellulose nanofibrils --- wood --- lignin --- TEMPO-oxidation --- cellulose nanomaterials --- nanoscale resolution --- cellulose --- chitosan nanoparticles --- bionanocomposites --- 5-fluorouracil --- in vitro drug release --- cytotoxicity assay --- colorectal cancer --- lyophilization --- plasma modification --- cell adhesion --- cellulose nanocrystals --- folic acid --- fluorescein isothiocyanate --- nanosystems --- physical adsorption --- cellular uptake --- cellular exometabolomics --- folate receptor-positive cancer cells --- dissolving pulp --- cellulose nanofibril --- nano silicon dioxide --- high strength --- n/a
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Bacterial nanocellulose (BNC), cellulose nanocrystals (CNCs), and cellulose nanofibers (CNFs) are three nanometric forms of the most abundant natural polymer (viz. cellulose), and are currently under the spotlight in numerous fields of modern science and technology. The eco-friendly connotations, peculiar features, and multiple functionalities of these nanoscale cellulosic substrates are being explored to engineer advanced nanocomposites and nanohybrid materials for application in manifold domains, such as mechanics, optics, electronics, energy, environment, biology, and medicine.The aim of this Special Issue titled “Advanced Nanocellulose-Based Materials: Production, Properties, and Applications” is to gather original research and review contributions from the world-leading scientists working with nanocellulose. Thus, research that is representative of the current developments dealing with the production methodologies, properties, and applications of nanocellulose-based materials (e.g., nanocomposites, hybrids, aerogels, hydrogels, films, and fibers) are presented in the Special Issue.
bacterial nanocellulose --- lignosulfonates --- mechanical performance --- thermal-oxidative stability --- ion-exchange membranes --- biobased separators --- ionic conductivity --- oxidized bacterial cellulose --- chitosan --- alginate --- layer-by-layer assembly --- multi-layered patches --- dexpanthenol --- wound healing --- cellulose nanocomposite --- ice-templating --- interface --- orientation --- mechanical properties --- cellulose nanofibrils --- wood --- lignin --- TEMPO-oxidation --- cellulose nanomaterials --- nanoscale resolution --- cellulose --- chitosan nanoparticles --- bionanocomposites --- 5-fluorouracil --- in vitro drug release --- cytotoxicity assay --- colorectal cancer --- lyophilization --- plasma modification --- cell adhesion --- cellulose nanocrystals --- folic acid --- fluorescein isothiocyanate --- nanosystems --- physical adsorption --- cellular uptake --- cellular exometabolomics --- folate receptor-positive cancer cells --- dissolving pulp --- cellulose nanofibril --- nano silicon dioxide --- high strength --- n/a
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Bacterial nanocellulose (BNC), cellulose nanocrystals (CNCs), and cellulose nanofibers (CNFs) are three nanometric forms of the most abundant natural polymer (viz. cellulose), and are currently under the spotlight in numerous fields of modern science and technology. The eco-friendly connotations, peculiar features, and multiple functionalities of these nanoscale cellulosic substrates are being explored to engineer advanced nanocomposites and nanohybrid materials for application in manifold domains, such as mechanics, optics, electronics, energy, environment, biology, and medicine.The aim of this Special Issue titled “Advanced Nanocellulose-Based Materials: Production, Properties, and Applications” is to gather original research and review contributions from the world-leading scientists working with nanocellulose. Thus, research that is representative of the current developments dealing with the production methodologies, properties, and applications of nanocellulose-based materials (e.g., nanocomposites, hybrids, aerogels, hydrogels, films, and fibers) are presented in the Special Issue.
Technology: general issues --- bacterial nanocellulose --- lignosulfonates --- mechanical performance --- thermal-oxidative stability --- ion-exchange membranes --- biobased separators --- ionic conductivity --- oxidized bacterial cellulose --- chitosan --- alginate --- layer-by-layer assembly --- multi-layered patches --- dexpanthenol --- wound healing --- cellulose nanocomposite --- ice-templating --- interface --- orientation --- mechanical properties --- cellulose nanofibrils --- wood --- lignin --- TEMPO-oxidation --- cellulose nanomaterials --- nanoscale resolution --- cellulose --- chitosan nanoparticles --- bionanocomposites --- 5-fluorouracil --- in vitro drug release --- cytotoxicity assay --- colorectal cancer --- lyophilization --- plasma modification --- cell adhesion --- cellulose nanocrystals --- folic acid --- fluorescein isothiocyanate --- nanosystems --- physical adsorption --- cellular uptake --- cellular exometabolomics --- folate receptor-positive cancer cells --- dissolving pulp --- cellulose nanofibril --- nano silicon dioxide --- high strength --- bacterial nanocellulose --- lignosulfonates --- mechanical performance --- thermal-oxidative stability --- ion-exchange membranes --- biobased separators --- ionic conductivity --- oxidized bacterial cellulose --- chitosan --- alginate --- layer-by-layer assembly --- multi-layered patches --- dexpanthenol --- wound healing --- cellulose nanocomposite --- ice-templating --- interface --- orientation --- mechanical properties --- cellulose nanofibrils --- wood --- lignin --- TEMPO-oxidation --- cellulose nanomaterials --- nanoscale resolution --- cellulose --- chitosan nanoparticles --- bionanocomposites --- 5-fluorouracil --- in vitro drug release --- cytotoxicity assay --- colorectal cancer --- lyophilization --- plasma modification --- cell adhesion --- cellulose nanocrystals --- folic acid --- fluorescein isothiocyanate --- nanosystems --- physical adsorption --- cellular uptake --- cellular exometabolomics --- folate receptor-positive cancer cells --- dissolving pulp --- cellulose nanofibril --- nano silicon dioxide --- high strength
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582.282.23 --- 581.17 --- 576.3 --- 576.3 General cytology. The cell as a biological system. General plan, chemical composition, physicochemical and molecular properties --- General cytology. The cell as a biological system. General plan, chemical composition, physicochemical and molecular properties --- 581.17 Physiology of the cell --- Physiology of the cell --- 582.282.23 Saccharomycetineae. Yeasts. Brettanomyces --- Saccharomycetineae. Yeasts. Brettanomyces --- Cytological technics --- Tissue culture --- Yearbooks. --- MAMMALS --- ISOLATION --- CELLS --- SYNCHRONIZATION --- MUTANTS --- TRANSFORMATION --- REVERTANTS --- MOLECULAR CLONING --- CLONES --- SCREENING --- SAMPLING --- SYNTHETIC MEDIA --- CELL CULTURE --- CRYOPRESERVATION --- BATCH CULTURE --- ENUCLEATED CELLS --- BINUCLEATED CELLS --- LIPOSOMES --- CARRIERS --- CELL FUSION --- CELL BIOLOGY --- METHODS --- ENZYMES --- MICROELECTROPHORESIS --- COMPLEMENT-MEDIATED ANTIBODY CYTOTOXICITY ASSAY --- TISSUE DISSOCIATION --- SOMATIC CELL HYBRIDS --- MICROINJECTION --- NUCLEIC ACID SYNTHESIS --- PERMEABILIZED CELLS --- MINISEGREGANT CELLS --- ANIMAL CELLS --- CELL NUCLEUS --- STAINING --- PLASMA MEMBRANE --- NEUROSPORA --- MITOCHONDRIA --- PROTOPLASTS --- YEASTS --- MOLECULAR GENETICS --- MUTAGENESIS --- CULTURES --- TETRAHYMENA --- AMOEBA --- ORGANS --- AMPHIBIA --- OESTROGEN RECEPTORS --- AUTORADIOGRAPHY --- PROTEINS --- DENSITY LABELLING --- NUCLEIC ACIDS --- LABELLING --- SPERMATOZOA --- FRACTIONATION --- LIVER --- RECONSTITUTION --- GROWTH --- GENETIC MAPS --- CELL CYCLE --- MICROMANIPULATIONS --- MONITORS --- CONTINUOUS CULTURES --- GERMINATION --- SPORULATION --- MICROSCOPIC TECHNIQUES
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The discovery of new drugs is one of pharmaceutical research's most exciting and challenging tasks. Unfortunately, the conventional drug discovery procedure is chronophagous and seldom successful; furthermore, new drugs are needed to address our clinical challenges (e.g., new antibiotics, new anticancer drugs, new antivirals).Within this framework, drug repositioning—finding new pharmacodynamic properties for already approved drugs—becomes a worthy drug discovery strategy.Recent drug discovery techniques combine traditional tools with in silico strategies to identify previously unaccounted properties for drugs already in use. Indeed, big data exploration techniques capitalize on the ever-growing knowledge of drugs' structural and physicochemical properties, drug–target and drug–drug interactions, advances in human biochemistry, and the latest molecular and cellular biology discoveries.Following this new and exciting trend, this book is a collection of papers introducing innovative computational methods to identify potential candidates for drug repositioning. Thus, the papers in the Special Issue In Silico Strategies for Prospective Drug Repositionings introduce a wide array of in silico strategies such as complex network analysis, big data, machine learning, molecular docking, molecular dynamics simulation, and QSAR; these strategies target diverse diseases and medical conditions: COVID-19 and post-COVID-19 pulmonary fibrosis, non-small lung cancer, multiple sclerosis, toxoplasmosis, psychiatric disorders, or skin conditions.
Medicine --- Pharmaceutical industries --- COVID-19 --- drug repurposing --- topological data analysis --- persistent Betti function --- SARS-CoV-2 --- network-based pharmacology --- combination therapy --- nucleoside GS-441524 --- fluoxetine --- synergy --- antidepressant --- natural compounds --- QSAR --- molecular docking --- drug repositioning --- UK Biobank --- vaccine --- LC-2/ad cell line --- drug discovery --- docking --- MM-GBSA calculation --- molecular dynamics --- cytotoxicity assay --- GWAS --- multiple sclerosis --- oxidative stress --- repurposing --- ADME-Tox --- bioinformatics --- complex network analysis --- modularity clustering --- ATC code --- hidradenitis suppurativa --- acne inversa --- transcriptome --- proteome --- comorbid disorder --- biomarker --- signaling pathway --- druggable gene --- drug-repositioning --- MEK inhibitor --- MM/GBSA --- Glide docking --- MD simulation --- MM/PBSA --- single-cell RNA sequencing --- pulmonary fibrosis --- biological networks --- p38α MAPK --- allosteric inhibitors --- in silico screening --- computer-aided drug discovery --- network analysis --- psychiatric disorders --- medications --- psychiatry --- mental disorders --- toxoplasmosis --- Toxoplasma gondii --- in vitro screening --- drug targets --- drug-disease interaction --- target-disease interaction --- DPP4 inhibitors --- lipid rafts
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