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The contribution of coronary stents in the prevention and treatment of complications of angioplasty in preventing restenosis is no longer contested. However, like any therapeutic progress, this technique has its limitations by generating a neo-pathology that includes stent restenosis and stent thrombosis with its dreaded fatal events are myocardial infarctions and sudden death. (6 Stopping antiplatelet therapy is the main risk of stent thrombosis DES as stent BMS. This risk raises the question of antithrombotic treatment alternative when the antiplatelet therapy should be stopped for surgery.The aim of this retrospective clinical study is to evaluate the prevalence (and incidence), predictors and impact of thrombosis bare stents (BMS) in non-diabetic patients.We believe that the incidence of stent thrombosis, as reported in prospective randomized trials or registries, is undervalued by at least 50%, recurrent thrombosis in the same patient and thrombosis of different stents procedure index, are generally not reported.Since November 2003, coated stents (DES) have been implanted in Belgium, especially in diabetic patients, these stents are associated with a higher rate of late thrombosis.Our clinical research work consists of a detailed analysis of the procedural data and long term follow up of patients treated in place bare metal stents (BMS) .So we analyzed 743 consecutive procedures from January l st, 2002 - December 2003 (before the DES era). During follow-up we evaluated the additional revascularization procedures and thrombosis of stents (classified as certain, probable and possible) .We intend to describe the incidence and impact of thrombosis bare stents, and a multivariate analysis to determine predictors. We also compare our results with those of patients (es) treated (es) by introduction of coated stents (DES) in the same period in the same hospital and the current literature L'apport des stents coronaires dans la prévention et le traitement des complications de l'angioplastie et dans la prévention des resténoses n'est plus contesté.Néanmoins, comme tout progrès thérapeutique, cette technique a ses limites en engendrant une néo-pathologie qui inclut la resténose intrastent et la thrombose de stent dont ses manifestations fatales redoutées sont l'infarctus myocardiques et la mort subites. (6)L'arrêt du traitement antiagrégant représente le principal risque de thrombose de stent actif comme de stent nu. Ce risque soulève la question du traitement antithrombotique de substitution lorsque le traitement antiagrégant doit être arrêté pour une chirurgie.Le but de cette recherche clinique rétrospective est d'évaluer la prévalence (et l'incidence), les facteurs prédictifs et l'impact des thromboses des stents nus (BMS) chez les patients non diabétiques.Nous pensons que l'incidence des thromboses de stents, telle que rapportée dans les études randomisées prospectives ou les registres, est sous-évaluée d'au moins 50%: les thromboses récidivantes chez le même patient et les thromboses de stents différents de la procédure index, ne sont généralement pas rapportées.Depuis novembre 2003, des stents enrobés (DES) sont implantés en Belgique, en particulier chez les patients diabétiques, ces stents sont associées à un taux plus élevé de thromboses tardives.Notre travail de recherche clinique consiste en une analyse en détail des données procédurales et de suivi à long terme des patients traités par mise en place de stents nus (BMS). Ainsi nous avons analysé 743 procédures consécutives du 01 janvier 2002 au 31 décembre 2003 (la majorité avant l'ère de DES en Belgique). Durant le suivi nous avons évalué les procédures de revascularisation supplémentaires et les thromboses de stents (classées en certaines, probables et possibles).Nous comptons décrire l'incidence et l'impact des thromboses des stents nus, et par une analyse multi-variée déterminer les facteurs prédictifs. Nous comparerons également nos résultats à ceux de patients(es) traités(es) par une mise en place de stents enrobés (DES) à la même période au sein du même hôpital et à la littérature actuelle.
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Athérosclérose. --- Thrombose des artères coronaires. --- Atherosclerosis. --- Coronary Thrombosis.
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This book has been written with the intention of providing an up-to-the minute review of acute coronary syndromes. Atherosclerotic coronary disease is still a leading cause of death within developed countries and not surprisingly, is significantly rising in others. Over the past decade the treatment of these syndromes has changed dramatically. The introduction of novel therapies has impacted the outcomes and surviving rates in such a way that the medical community need to be up to date almost on a "daily bases". It is hoped that this book will provide a timely update on acute coronary syndromes and prove to be an invaluable resource for practitioners seeking new and innovative ways to deliver the best possible care to their patients.
Coronary heart disease. --- Coronary arteries --- Coronary arteriosclerosis --- Coronary disease --- Coronary thrombosis --- Ischemic heart disease --- Myocardial ischemia --- Heart --- Type A behavior --- Diseases --- Cardiovascular medicine
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Translational Research in Coronary Artery Disease: Pathophysiology to Treatment covers the entire spectrum of basic science, genetics, drug treatment, and interventions for coronary artery disease. With an emphasis on vascular biology, this reference fully explains the fundamental aspects of coronary artery disease pathophysiology. Included are important topics, including endothelial function, endothelial injury, and endothelial repair in various disease states, vascular smooth muscle function and its interaction with the endothelium, and the interrelationship between inflammatory biology and vascular function. By providing this synthesis of current research literature, this reference allows the cardiovascular scientist and practitioner to access everything they need from one source. --
Coronary heart disease --- Pathophysiology. --- Research. --- Treatment. --- Coronary arteries --- Coronary arteriosclerosis --- Coronary disease --- Coronary thrombosis --- Ischemic heart disease --- Myocardial ischemia --- Heart --- Type A behavior --- Diseases --- Interventional cardiology
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This book discusses the benefits of application of different psychotherapy techniques, in addition to optimal medical approaches, in patients with ischemic heart disease. It explains the theoretical basis for use of these techniques, discusses the scientific evidence for their efficacy, and identifies important practical issues. Detailed attention is devoted to both well-established and recently developed approaches of proven value, as well as to future applications. In addition, practical insights are provided into the most effective ways of integrating psychotherapy with medical activities in hospitals, outpatient clinics, and rehabilitation centers. The authors are world experts in the fields of psychotherapy, pharmacology, and cardiology, who collectively provide a sound foundation for an interdisciplinary approach to patients with ischemic heart disease. Psychotherapy for Ischemic Heart Disease is both a textbook and a practical manual aimed particularly at cardiologists, psychologists, psychotherapists, and psychiatrists, but also internal medicine specialists, cardiac surgeons, general practitioners, rehabilitation doctors, students, nurses, and patients.
Medicine. --- Cardiology. --- Medicine & Public Health. --- Coronary heart disease. --- Coronary arteries --- Coronary arteriosclerosis --- Coronary disease --- Coronary thrombosis --- Ischemic heart disease --- Myocardial ischemia --- Diseases --- Heart --- Type A behavior --- Internal medicine
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Coronary heart disease. --- Coronary arteries --- Coronary arteriosclerosis --- Coronary disease --- Coronary thrombosis --- Ischemic heart disease --- Myocardial ischemia --- Heart --- Type A behavior --- Diseases
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Fast Facts: Acute Coronary Syndromes is an international evidence-based primer that focuses on optimizing patient outcomes via accurate initial diagnosis, appropriate risk stratification and proper therapeutic decision-making in line with both American and European management guidelines.
Coronary heart disease. --- Coronary arteries --- Coronary arteriosclerosis --- Coronary disease --- Coronary thrombosis --- Ischemic heart disease --- Myocardial ischemia --- Heart --- Type A behavior --- Diseases
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Coronary artery disease is the most common cause of morbidity and mortality in the developed and developing world. This concise pocketbook highlights the practical aspects of management, and establishes straightforward management plans. It uses a team approach to address all of the issues and to optimise care.
Coronary heart disease. --- Heart --- Cardiac diseases --- Heart diseases --- Cardiology --- Coronary arteries --- Coronary arteriosclerosis --- Coronary disease --- Coronary thrombosis --- Ischemic heart disease --- Myocardial ischemia --- Type A behavior --- Diseases. --- Diseases
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Coronary heart disease. --- Ventricular fibrillation. --- Fibrillation, Ventricular --- Arrhythmia --- Cardiac arrest --- Coronary arteries --- Coronary arteriosclerosis --- Coronary disease --- Coronary thrombosis --- Ischemic heart disease --- Myocardial ischemia --- Heart --- Type A behavior --- Diseases
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Coronary heart disease. --- Heart --- Coronary arteries --- Coronary arteriosclerosis --- Coronary disease --- Coronary thrombosis --- Ischemic heart disease --- Myocardial ischemia --- Type A behavior --- Cardiac diseases --- Heart diseases --- Cardiology --- Diseases. --- Diseases
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