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Fundamentals of Protein Structure and Function Engelbert Buxbaum, Dr. rer. nat. This book serves as an introduction to the fundamentals of protein structure and function. Starting with their make up from simple building blocks called amino acids, the 3-dimensional structure of proteins is explained. This is followed by an introduction into enzymology and modern concepts of enzyme kinetics, taking into account the physiological and medical significance of this often neglected topic. Also covered in the text are enzymes, biocatalysts, enzyme kinetics, hemoglobin, myoglobin, prion proteins, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins into mitochondria, transport of proteins between cell compartments, transport of solutes across membranes, analytic techniques, protein-ligand interactions, protein purification, and protein structure, size and shape, emphasizing the link between protein structure, physiological function and medical significance. This book is an introductory text for researchers in protein biochemistry, molecular biology, cell biology, chemistry, biophysics and biomedical research. The book also makes an ideal textbook for graduate and advanced undergraduate courses in protein structure and function, and a supplementary text for related courses. About the Author Dr. Buxbaum is a biochemist with interest in enzymology and protein science. Dr. Buxbaum has been working on the biochemistry of membrane transport proteins for almost 20 years and has taught courses in biochemistry and molecular medicine at several universities. "The analytical descriptions of structure, biophysics and function of proteins is an extremely important aspect of today's education in biochemistry." Martin Sagermann, Ph.D. University of California, Santa Barbara

Proteins --- Structure --- Protein Conformation --- 577.122 --- 577.122 Protein metabolism --- Protein metabolism --- Conformation, Protein --- Conformations, Protein --- Protein Conformations --- Protein Folding --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- physiology --- Proteins - Structure

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"Proteins: Structure and Function is a comprehensive introduction to the study of proteins and their importance to modern biochemistry. Each chapter addresses the structure and function of proteins with a definitive theme designed to enhance student understanding. The latest developments in the field are included and key concepts introduced in a user-friendly way to ensure that students are able to grasp the essentials before moving on to more advanced study and analysis of proteins. An invaluable resource for students of Biochemistry, Molecular Biology, Medicine and Chemistry providing a modern approach to the subject of proteins."--Jacket.

Proteins --- Protein Conformation. --- Protéines --- chemistry. --- genetics. --- metabolism. --- Protein Conformation --- 577.122 --- 577.122 Protein metabolism --- Protein metabolism --- Conformation, Protein --- Conformations, Protein --- Protein Conformations --- Protein Folding --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- chemistry --- genetics --- metabolism --- Acqui 2006

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Glutathione conformations --- Glx/GABA --- Neurodegenerative diseases --- Neuropsychiatric diseases --- Multi-modal Imaging --- Machine Learning --- Data Mining --- Cognitive Decline --- Biomarkers

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Proteins --- Enzymes --- Protein Conformation. --- Proteins. --- Enzymes. --- Protéines --- Périodiques. --- Biocatalysts --- Gene Products, Protein --- Gene Proteins --- Protein Gene Products --- Proteins, Gene --- Conformation, Protein --- Conformations, Protein --- Protein Conformations --- Ferments --- Soluble ferments --- Molecular Mechanisms of Pharmacological Action --- Protein Folding --- Catalysts --- Enzymology --- Biocatalyst --- Enzyme --- Protein

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"Intrinsically Disordered Proteins: Dynamics, Binding, and Function thoroughly examines and ties together the fundamental biochemical functions of intrinsically disordered proteins (IDPs) and intrinsically disordered regions (IDRs), including signaling, binding, and regulation, with the methodology for study and the associated pathways for drug design and therapeutic intervention. The role of new mechanistic, computational, and experimental approaches in IDP study are explored in depth, with methods for the characterization of IDP dynamics; models, simulations, and mechanisms of IDP and IDR binding; and biological and medical implications of IDP dynamics prominently featured. Written and edited by leading scientists in the field, this book explores groundbreaking areas such as ensemble descriptions of IDPs and IDRs, single-molecule studies of IDPs and IDRs, IDPs and IDRs in membraneless organelles, and molecular mechanisms of fibrillation of IDPs. Intrinsically Disordered Proteins provides students and researchers in biochemistry, molecular biology, and applied microbiology with a comprehensive and updated discussion of the complex dynamics of IDPs and IDRs."--

Proteins --- Structure. --- Intrinsically Disordered Proteins --- Carrier Proteins. --- Protein Conformation --- physiology. --- Conformation, Protein --- Conformations, Protein --- Protein Conformations --- Protein Folding --- Binding Protein --- Binding Proteins --- Transport Proteins --- Protein, Binding --- Proteins, Binding --- Proteins, Carrier --- Proteins, Transport --- Protein Binding --- Receptors, Transferrin --- Carrier Protein --- Transport Protein --- Protein, Carrier --- Protein, Transport