Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Many biodegradation pathways, both aerobic and anaerobic, have already been characterised, and the phylogenetic relationships among catabolic genes within them have been studied. However, new biodegradation activities and their coding genes are continuously being reported, including those involved in the catabolism of emerging contaminants and those generally regarded as non-biodegradable. Gene regulation is also an important issue for the efficient biodegradation of contaminants. Specific induction by the substrate and over-imposed global regulatory networks adjust the expression of the biodegradation genes to meet bacterial physiological needs. New biodegradation pathways can be assembled in a particular strain or in a bacterial consortium by recruiting biodegradation genes from different origins through horizontal gene transfer. The abundance and diversity of biodegradation genes, analysed by either genomic or metagenomic approaches, constitute valuable indicators of the biodegradation potential of a particular environmental niche. This knowledge paves the way to systems metabolic engineering approaches to valorise biowaste for the production of value-added products.

Research & information: general --- Biology, life sciences --- tetralin --- Sphingopyxis granuli strain TFA --- Rhodococcus sp. strain TFB --- redox proteins --- carbon catabolite repression --- plastics --- biodegradation --- sustainability --- upcycling --- biotransformations --- polyethylene terephthalate --- terephthalate --- ethylene glycol --- biphenyl --- bph gene --- integrative conjugative element --- genome sequence --- LysR --- transcription factor --- Acinetobacter --- LTTR --- benzoate --- muconate --- synergism --- biosensor --- naphthalene --- toluene --- hydrocarbons --- plant growth promotion --- bioremediation --- Pseudomonas --- soil pollution --- phytoremediation --- rhizoremediation --- diesel --- bacteria --- consortium --- metagenomics --- PAHs --- TPH --- regulation --- anaerobic --- Azoarcus --- promoter architecture --- bioethanol --- furfural --- ALE --- AraC --- sterols --- bile acids --- steroid hormones --- 9,10-seco pathway --- 4,5-seco pathway --- 2,3-seco pathway --- xenobiotics --- Carbaryl --- horizontal gene transfer --- mobile genetic elements --- transposons --- integrative conjugative elements --- pathway assembly --- evolution --- Sphingopyxis lindanitolerans --- pesticide --- complete genome sequence --- pangenome --- γ-HCH degradation --- lin genes --- testosterone --- steroid --- catabolism --- transcriptomic --- valorisation --- catabolic pathway --- mobile DNA --- anaerobic biodegradation --- gene regulation --- tetralin --- Sphingopyxis granuli strain TFA --- Rhodococcus sp. strain TFB --- redox proteins --- carbon catabolite repression --- plastics --- biodegradation --- sustainability --- upcycling --- biotransformations --- polyethylene terephthalate --- terephthalate --- ethylene glycol --- biphenyl --- bph gene --- integrative conjugative element --- genome sequence --- LysR --- transcription factor --- Acinetobacter --- LTTR --- benzoate --- muconate --- synergism --- biosensor --- naphthalene --- toluene --- hydrocarbons --- plant growth promotion --- bioremediation --- Pseudomonas --- soil pollution --- phytoremediation --- rhizoremediation --- diesel --- bacteria --- consortium --- metagenomics --- PAHs --- TPH --- regulation --- anaerobic --- Azoarcus --- promoter architecture --- bioethanol --- furfural --- ALE --- AraC --- sterols --- bile acids --- steroid hormones --- 9,10-seco pathway --- 4,5-seco pathway --- 2,3-seco pathway --- xenobiotics --- Carbaryl --- horizontal gene transfer --- mobile genetic elements --- transposons --- integrative conjugative elements --- pathway assembly --- evolution --- Sphingopyxis lindanitolerans --- pesticide --- complete genome sequence --- pangenome --- γ-HCH degradation --- lin genes --- testosterone --- steroid --- catabolism --- transcriptomic --- valorisation --- catabolic pathway --- mobile DNA --- anaerobic biodegradation --- gene regulation

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Many biodegradation pathways, both aerobic and anaerobic, have already been characterised, and the phylogenetic relationships among catabolic genes within them have been studied. However, new biodegradation activities and their coding genes are continuously being reported, including those involved in the catabolism of emerging contaminants and those generally regarded as non-biodegradable. Gene regulation is also an important issue for the efficient biodegradation of contaminants. Specific induction by the substrate and over-imposed global regulatory networks adjust the expression of the biodegradation genes to meet bacterial physiological needs. New biodegradation pathways can be assembled in a particular strain or in a bacterial consortium by recruiting biodegradation genes from different origins through horizontal gene transfer. The abundance and diversity of biodegradation genes, analysed by either genomic or metagenomic approaches, constitute valuable indicators of the biodegradation potential of a particular environmental niche. This knowledge paves the way to systems metabolic engineering approaches to valorise biowaste for the production of value-added products.

Research & information: general --- Biology, life sciences --- tetralin --- Sphingopyxis granuli strain TFA --- Rhodococcus sp. strain TFB --- redox proteins --- carbon catabolite repression --- plastics --- biodegradation --- sustainability --- upcycling --- biotransformations --- polyethylene terephthalate --- terephthalate --- ethylene glycol --- biphenyl --- bph gene --- integrative conjugative element --- genome sequence --- LysR --- transcription factor --- Acinetobacter --- LTTR --- benzoate --- muconate --- synergism --- biosensor --- naphthalene --- toluene --- hydrocarbons --- plant growth promotion --- bioremediation --- Pseudomonas --- soil pollution --- phytoremediation --- rhizoremediation --- diesel --- bacteria --- consortium --- metagenomics --- PAHs --- TPH --- regulation --- anaerobic --- Azoarcus --- promoter architecture --- bioethanol --- furfural --- ALE --- AraC --- sterols --- bile acids --- steroid hormones --- 9,10-seco pathway --- 4,5-seco pathway --- 2,3-seco pathway --- xenobiotics --- Carbaryl --- horizontal gene transfer --- mobile genetic elements --- transposons --- integrative conjugative elements --- pathway assembly --- evolution --- Sphingopyxis lindanitolerans --- pesticide --- complete genome sequence --- pangenome --- γ-HCH degradation --- lin genes --- testosterone --- steroid --- catabolism --- transcriptomic --- valorisation --- catabolic pathway --- mobile DNA --- anaerobic biodegradation --- gene regulation

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

This book collected recent innovative research and review articles on analytical techniques, production protocols, biotechnological tools, and new insights into bioactivities of ginsenosides including the effects on epithelial-mesenchymal transition, hippocampal neurogenesis and inflammation as well as on diseases such as ischemic stroke, autoimmune diseases, and allergic disorders. Additionally, the analysis through molecular docking and an overview of the Panax ginseng pharmacopuncture were also presented.

Ginseng berries --- UPLC-QTOF/MS --- HR-MAS NMR spectroscopy --- ginsenoside --- primary metabolite --- notoginseng leaf triterpenes --- HMGB1 --- cerebral ischemia and reperfusion injury --- inflammation --- MAPK --- NF-κB --- Panax ginseng --- wild ginseng --- pharmacopuncture --- safety --- clinical trials --- ocotillol type ginsenoside epimers --- stereoselective ADME characteristics --- molecular docking analysis --- homology modeling --- molecular interaction --- Rg3 --- Th17 --- RORγt --- EAE --- Lactobacillus ginsenosidimutans --- complete genome sequence --- novel glycoside hydrolases --- bioconversion --- recombinant enzyme --- ginsenoside Rg3(S) --- gram unit production --- Asian ginseng --- American ginseng --- Panax quinquefolium L. --- ginsenosides --- anti-inflammation --- pro-resolving --- ginseng --- macrophage --- M2 polarization --- ginsenoside CK --- neurogenesis --- cell proliferation --- neuroprotection --- dammarane-type triterpene saponin --- ginsenoside MT1 --- transglycosylation --- biotransformation --- biotechnology --- Anxa2 --- epithelial-mesenchymal transition --- (20S)G-Rh2 --- bioreactor --- cell suspension --- hairy root --- polyploidy --- protoplast --- Panax sp. --- polysaccharides --- allergy --- immune system --- n/a --- compound M1 --- hepatoprotective --- anti-cancer --- anti-diabetic