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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Science: general issues --- Neurosciences --- co-transmission --- co-localization --- co-release --- Co-existence --- Neurotransmitter segregation --- Neurotransmitter complexity --- Neuropeptides --- monoamines

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Compared to other sensory systems, the auditory system has evolved a large number of subthalamic nuclei each devoted to processing distinct features of sound stimuli. This information once extracted is then re-assembled to form the percept the acoustic world around us. The well-understood function of many of these auditory nuclei has enhanced our understanding of inhibition's role in shaping their responses from easily distinguished inhibitory inputs. In particular, neurons devoted to processing the location of sound sources receive a complement of discrete inputs for which in vivo activity and function are well understood. Investigation of these areas has led to significant advances in understanding the development, physiology, and mechanistic underpinnings of inhibition that apply broadly to neuroscience.

Auditory perception --- Neurons --- Neurology. --- Cytology. --- Nerve cells --- Neurocytes --- Cells --- Nervous system --- Sound perception --- Hearing --- Perception --- Word deafness --- Medicine --- Neuropsychiatry --- Diseases --- Gap Junctions --- Sound Localization --- GABA --- inhibition --- plasticity --- Nitric Oxide --- MNTB --- Glycine --- co-release