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oncology --- cancer --- clinical practice --- biology --- Oncology. Neoplasms
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From the moment it came out in 2012, Psychoanalytic Approaches to Concerns about Subjectivity set out to bring together a certain diversity of topics and invite national and international authors, thus consolidating a project that should be attractive not only to the academic public of the psychoanalytic field, but also to all those who wish to approach, establish a dialogue or address certain epistemological, scientific and theoretical issues in the field of psychoanalysis. In this new volume, the reader will find three sections that the editors have called conceptual theoretical reviews; contemporary problems of clinical practice; and psychoanalysis applied to the understanding of social conflicts. Desde el momento en que salió a la luz en el año 2012, Abordajes psicoanalíticos a inquietudes sobre la subjetividad se propuso reunir cierta diversidad de temas e invitar a autores nacionales e internacionales, consolidando así un proyecto que ha de resultar atractivo no solo para el público académico del ámbito psicoanalítico, sino también para todos aquellos quienes deseen acercarse, establecer un diálogo o abordar ciertas problemáticas de corte epistemológico, científico y teórico en el campo del psicoanálisis. En este nuevo volumen, el lector encontrará tres secciones que los editores han denominado revisiones teóricos conceptuales; problemas contemporáneos de la práctica clínica, y psicoanálisis aplicado a la comprensión de los conflictos sociales.
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clinical practice --- public health --- health research --- continuing medical education --- honduras
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From the moment it came out in 2012, Psychoanalytic Approaches to Concerns about Subjectivity set out to bring together a certain diversity of topics and invite national and international authors, thus consolidating a project that should be attractive not only to the academic public of the psychoanalytic field, but also to all those who wish to approach, establish a dialogue or address certain epistemological, scientific and theoretical issues in the field of psychoanalysis. In this new volume, the reader will find three sections that the editors have called conceptual theoretical reviews; contemporary problems of clinical practice; and psychoanalysis applied to the understanding of social conflicts. Desde el momento en que salió a la luz en el año 2012, Abordajes psicoanalíticos a inquietudes sobre la subjetividad se propuso reunir cierta diversidad de temas e invitar a autores nacionales e internacionales, consolidando así un proyecto que ha de resultar atractivo no solo para el público académico del ámbito psicoanalítico, sino también para todos aquellos quienes deseen acercarse, establecer un diálogo o abordar ciertas problemáticas de corte epistemológico, científico y teórico en el campo del psicoanálisis. En este nuevo volumen, el lector encontrará tres secciones que los editores han denominado revisiones teóricos conceptuales; problemas contemporáneos de la práctica clínica, y psicoanálisis aplicado a la comprensión de los conflictos sociales.
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Traumatic brain injury (TBI) is a major cause of death and disability and one of the greatest unmet needs in medicine and public health. TBI not only has devastating effects on patients and their relatives but results in huge direct and indirect costs to society. Although guidelines for the management of patients have been developed and more than 200 clinical trials have been conducted, they have resulted in few improvements in clinical outcomes and no effective therapies approved for TBI. It is now apparent that the heterogeneity of clinical TBI is underlain by molecular phenotypes more complex and interactive than initially conceived and current approaches to the characterization, management and outcome prediction of TBI are antiquated, unidimensional and inadequate to capture the interindividual pathophysiological heterogeneity. Recent advances in proteomics and biomarker development provide unparalleled opportunities for unraveling substantial injury-specific and patient-specific variability and refining disease characterization. The identification of novel, sensitive, objective tools, referred to as biomarkers, can revolutionize pathophysiological insights, enable targeted therapies and personalized approaches to clinical management. In this Research Topic, we present novel approaches that provide an infrastructure for discovery and validation of new biomarkers of acute brain injury. These techniques include refined mass spectrometry technology and high throughput immunoblot techniques. Output from these approaches can identify potential candidate biomarkers employing systems biology and data mining methods. In this Research Topic, we present novel approaches that provide an infrastructure for discovery and validation of new biomarkers of acute brain injury. These techniques include refined mass spectrometry technology and high throughput immunoblot techniques. Output from these approaches can identify potential candidate biomarkers employing systems biology and data mining methods. Finally, suggestions are provided for the way forward, with an emphasis on need for a multidimensional approach that integrate a panel of pathobiologically diverse biomarkers with clinical variables and imaging-based assessments to improve diagnosis and classification of TBI and to develop best clinical practice guidelines.
Brain damage. --- Biochemical markers. --- Traumatic Brain Injury --- Brain Injury --- discovery --- clinical practice --- biomarker --- Traumatic Brain Injury --- Brain Injury --- discovery --- clinical practice --- biomarker
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Health Sciences --- General and Others --- clinical science --- clinical practice --- health policy --- healthcare delivery --- medical education
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medicine --- clinical practice --- comorbidity --- differential diagnosis --- extraordinary treatment --- Internal medicine --- Médecine interne --- Medicine, Internal --- Medicine
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Traumatic brain injury (TBI) is a major cause of death and disability and one of the greatest unmet needs in medicine and public health. TBI not only has devastating effects on patients and their relatives but results in huge direct and indirect costs to society. Although guidelines for the management of patients have been developed and more than 200 clinical trials have been conducted, they have resulted in few improvements in clinical outcomes and no effective therapies approved for TBI. It is now apparent that the heterogeneity of clinical TBI is underlain by molecular phenotypes more complex and interactive than initially conceived and current approaches to the characterization, management and outcome prediction of TBI are antiquated, unidimensional and inadequate to capture the interindividual pathophysiological heterogeneity. Recent advances in proteomics and biomarker development provide unparalleled opportunities for unraveling substantial injury-specific and patient-specific variability and refining disease characterization. The identification of novel, sensitive, objective tools, referred to as biomarkers, can revolutionize pathophysiological insights, enable targeted therapies and personalized approaches to clinical management. In this Research Topic, we present novel approaches that provide an infrastructure for discovery and validation of new biomarkers of acute brain injury. These techniques include refined mass spectrometry technology and high throughput immunoblot techniques. Output from these approaches can identify potential candidate biomarkers employing systems biology and data mining methods. In this Research Topic, we present novel approaches that provide an infrastructure for discovery and validation of new biomarkers of acute brain injury. These techniques include refined mass spectrometry technology and high throughput immunoblot techniques. Output from these approaches can identify potential candidate biomarkers employing systems biology and data mining methods. Finally, suggestions are provided for the way forward, with an emphasis on need for a multidimensional approach that integrate a panel of pathobiologically diverse biomarkers with clinical variables and imaging-based assessments to improve diagnosis and classification of TBI and to develop best clinical practice guidelines.
Brain damage. --- Biochemical markers. --- Traumatic Brain Injury --- Brain Injury --- discovery --- clinical practice --- biomarker
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From the moment it came out in 2012, Psychoanalytic Approaches to Concerns about Subjectivity set out to bring together a certain diversity of topics and invite national and international authors, thus consolidating a project that should be attractive not only to the academic public of the psychoanalytic field, but also to all those who wish to approach, establish a dialogue or address certain epistemological, scientific and theoretical issues in the field of psychoanalysis. In this new volume, the reader will find three sections that the editors have called conceptual theoretical reviews; contemporary problems of clinical practice; and psychoanalysis applied to the understanding of social conflicts. Desde el momento en que salió a la luz en el año 2012, Abordajes psicoanalíticos a inquietudes sobre la subjetividad se propuso reunir cierta diversidad de temas e invitar a autores nacionales e internacionales, consolidando así un proyecto que ha de resultar atractivo no solo para el público académico del ámbito psicoanalítico, sino también para todos aquellos quienes deseen acercarse, establecer un diálogo o abordar ciertas problemáticas de corte epistemológico, científico y teórico en el campo del psicoanálisis. En este nuevo volumen, el lector encontrará tres secciones que los editores han denominado revisiones teóricos conceptuales; problemas contemporáneos de la práctica clínica, y psicoanálisis aplicado a la comprensión de los conflictos sociales.
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