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The present book recapitulates the articles published within the Special Issue "Cartilage Repair and Regeneration: Focus on Multi-Disciplinary Strategies", Applied Sciences, MDPI, dealing with the innovative multi-disciplinary therapeutic approaches for musculoskeletal diseases. In particular the published studies space from advanced 3D bioprinting technology to obtain a scaffold with different zonal cell densities, and biphasic scaffold (ChondroMimetic) construction, pass through the comparison of different techniques for cartilage regeneration such as of mosaicplasty and matrix-assisted autologous chondrocyte transplantation (MACT) and histopathological features of osteochondral units, and end with the considerations regarding development of bioreactors able to mimic the biomechanical load on chondrocytes in vitro, giving some interesting insights in this specific scientific field.

Medicine --- Pharmacology --- mesenchymal stem cells --- tissue engineering --- chondrogenesis --- osteoarthritis --- bioreactor --- mechanical stimuli --- physical stimulation --- compression --- shear stress --- hydrostatic pressure --- osteonecrosis --- osteochondral unit --- tissue remodelling and repair --- multi-targeted approach --- mosaicplasty --- MACT --- ACI --- scaffold --- osteochondral autologous transplantation --- OAT --- cartilage --- knee --- biphasic scaffold --- osteochondral defect --- cartilage repair --- quantitative MRI --- calcium phosphate --- bioprinting --- biofabrication --- articular cartilage --- human chondrocytes --- cell density --- cell gradient --- 3D bioprinting --- ChondroMimetic --- cartilage regeneration --- osteochondral repair --- matrix-assisted autologous chondrocyte transplantation --- magneto-responsive techniques --- biomechanical stimuli --- multi-disciplinary approach

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• Reference Manager
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The present book recapitulates the articles published within the Special Issue "Cartilage Repair and Regeneration: Focus on Multi-Disciplinary Strategies", Applied Sciences, MDPI, dealing with the innovative multi-disciplinary therapeutic approaches for musculoskeletal diseases. In particular the published studies space from advanced 3D bioprinting technology to obtain a scaffold with different zonal cell densities, and biphasic scaffold (ChondroMimetic) construction, pass through the comparison of different techniques for cartilage regeneration such as of mosaicplasty and matrix-assisted autologous chondrocyte transplantation (MACT) and histopathological features of osteochondral units, and end with the considerations regarding development of bioreactors able to mimic the biomechanical load on chondrocytes in vitro, giving some interesting insights in this specific scientific field.

Medicine --- Pharmacology --- mesenchymal stem cells --- tissue engineering --- chondrogenesis --- osteoarthritis --- bioreactor --- mechanical stimuli --- physical stimulation --- compression --- shear stress --- hydrostatic pressure --- osteonecrosis --- osteochondral unit --- tissue remodelling and repair --- multi-targeted approach --- mosaicplasty --- MACT --- ACI --- scaffold --- osteochondral autologous transplantation --- OAT --- cartilage --- knee --- biphasic scaffold --- osteochondral defect --- cartilage repair --- quantitative MRI --- calcium phosphate --- bioprinting --- biofabrication --- articular cartilage --- human chondrocytes --- cell density --- cell gradient --- 3D bioprinting --- ChondroMimetic --- cartilage regeneration --- osteochondral repair --- matrix-assisted autologous chondrocyte transplantation --- magneto-responsive techniques --- biomechanical stimuli --- multi-disciplinary approach

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This book covedered high-quality contributions (original research articles or review papers) providing a picture on innovations in microbial fermentative processes, including improvements of quality/safety of fermented foods and beverages, production of high added-values products, and valorization/recovery of agro-food wastes.

Technology: general issues --- Biotechnology --- simultaneous saccharification and cultivation (SSC) --- intensive multiple sequential batch cultivation --- thermotolerant yeast --- Kluyveromyces marxianus --- ethanol production --- smoking with open fire --- PAH --- industrial smoking --- clavulanic acid --- Streptomyces clavuligerus --- cell morphology --- shear stress --- high cell density cultivation (HCDC) --- intensive multiple sequential batch (IMSB) --- cell cultivation --- fed-batch at cell level (FBC) --- S. cerevisiae --- dextrin --- bioreactor --- chain elongation --- carboxylate platform --- medium-chain fatty acids --- carboxylic acids --- mixed culture fermentation --- biocontrol --- Bacillus velezensis --- volatile organic compounds --- vascular wilt pathogens --- GABA --- Indonesian fermented foods --- glutamate decarboxylase --- lactic acid bacteria --- L. plantarum --- feast/famine conditions --- industrial-scale bioreactor --- metabolomics --- metabolic response --- penicillin --- Penicillium chrysogenum --- scale-down --- children --- double fortification --- fermented milk --- iron and zinc --- stunting --- synbiotic --- wine --- HS-SPME-GC/MS --- multivariate statistical analysis --- calibration --- whole-plant corn silage --- bacterial community --- fungal community --- metabolites --- fermentation quality --- aerobic stability --- succession pattern --- fermentation process --- n/a

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• Reference Manager
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This book covedered high-quality contributions (original research articles or review papers) providing a picture on innovations in microbial fermentative processes, including improvements of quality/safety of fermented foods and beverages, production of high added-values products, and valorization/recovery of agro-food wastes.

Technology: general issues --- Biotechnology --- simultaneous saccharification and cultivation (SSC) --- intensive multiple sequential batch cultivation --- thermotolerant yeast --- Kluyveromyces marxianus --- ethanol production --- smoking with open fire --- PAH --- industrial smoking --- clavulanic acid --- Streptomyces clavuligerus --- cell morphology --- shear stress --- high cell density cultivation (HCDC) --- intensive multiple sequential batch (IMSB) --- cell cultivation --- fed-batch at cell level (FBC) --- S. cerevisiae --- dextrin --- bioreactor --- chain elongation --- carboxylate platform --- medium-chain fatty acids --- carboxylic acids --- mixed culture fermentation --- biocontrol --- Bacillus velezensis --- volatile organic compounds --- vascular wilt pathogens --- GABA --- Indonesian fermented foods --- glutamate decarboxylase --- lactic acid bacteria --- L. plantarum --- feast/famine conditions --- industrial-scale bioreactor --- metabolomics --- metabolic response --- penicillin --- Penicillium chrysogenum --- scale-down --- children --- double fortification --- fermented milk --- iron and zinc --- stunting --- synbiotic --- wine --- HS-SPME-GC/MS --- multivariate statistical analysis --- calibration --- whole-plant corn silage --- bacterial community --- fungal community --- metabolites --- fermentation quality --- aerobic stability --- succession pattern --- fermentation process