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The present book recapitulates the articles published within the Special Issue "Cartilage Repair and Regeneration: Focus on Multi-Disciplinary Strategies", Applied Sciences, MDPI, dealing with the innovative multi-disciplinary therapeutic approaches for musculoskeletal diseases. In particular the published studies space from advanced 3D bioprinting technology to obtain a scaffold with different zonal cell densities, and biphasic scaffold (ChondroMimetic) construction, pass through the comparison of different techniques for cartilage regeneration such as of mosaicplasty and matrix-assisted autologous chondrocyte transplantation (MACT) and histopathological features of osteochondral units, and end with the considerations regarding development of bioreactors able to mimic the biomechanical load on chondrocytes in vitro, giving some interesting insights in this specific scientific field.

Medicine --- Pharmacology --- mesenchymal stem cells --- tissue engineering --- chondrogenesis --- osteoarthritis --- bioreactor --- mechanical stimuli --- physical stimulation --- compression --- shear stress --- hydrostatic pressure --- osteonecrosis --- osteochondral unit --- tissue remodelling and repair --- multi-targeted approach --- mosaicplasty --- MACT --- ACI --- scaffold --- osteochondral autologous transplantation --- OAT --- cartilage --- knee --- biphasic scaffold --- osteochondral defect --- cartilage repair --- quantitative MRI --- calcium phosphate --- bioprinting --- biofabrication --- articular cartilage --- human chondrocytes --- cell density --- cell gradient --- 3D bioprinting --- ChondroMimetic --- cartilage regeneration --- osteochondral repair --- matrix-assisted autologous chondrocyte transplantation --- magneto-responsive techniques --- biomechanical stimuli --- multi-disciplinary approach --- mesenchymal stem cells --- tissue engineering --- chondrogenesis --- osteoarthritis --- bioreactor --- mechanical stimuli --- physical stimulation --- compression --- shear stress --- hydrostatic pressure --- osteonecrosis --- osteochondral unit --- tissue remodelling and repair --- multi-targeted approach --- mosaicplasty --- MACT --- ACI --- scaffold --- osteochondral autologous transplantation --- OAT --- cartilage --- knee --- biphasic scaffold --- osteochondral defect --- cartilage repair --- quantitative MRI --- calcium phosphate --- bioprinting --- biofabrication --- articular cartilage --- human chondrocytes --- cell density --- cell gradient --- 3D bioprinting --- ChondroMimetic --- cartilage regeneration --- osteochondral repair --- matrix-assisted autologous chondrocyte transplantation --- magneto-responsive techniques --- biomechanical stimuli --- multi-disciplinary approach

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

The present book recapitulates the articles published within the Special Issue "Cartilage Repair and Regeneration: Focus on Multi-Disciplinary Strategies", Applied Sciences, MDPI, dealing with the innovative multi-disciplinary therapeutic approaches for musculoskeletal diseases. In particular the published studies space from advanced 3D bioprinting technology to obtain a scaffold with different zonal cell densities, and biphasic scaffold (ChondroMimetic) construction, pass through the comparison of different techniques for cartilage regeneration such as of mosaicplasty and matrix-assisted autologous chondrocyte transplantation (MACT) and histopathological features of osteochondral units, and end with the considerations regarding development of bioreactors able to mimic the biomechanical load on chondrocytes in vitro, giving some interesting insights in this specific scientific field.

mesenchymal stem cells --- tissue engineering --- chondrogenesis --- osteoarthritis --- bioreactor --- mechanical stimuli --- physical stimulation --- compression --- shear stress --- hydrostatic pressure --- osteonecrosis --- osteochondral unit --- tissue remodelling and repair --- multi-targeted approach --- mosaicplasty --- MACT --- ACI --- scaffold --- osteochondral autologous transplantation --- OAT --- cartilage --- knee --- biphasic scaffold --- osteochondral defect --- cartilage repair --- quantitative MRI --- calcium phosphate --- bioprinting --- biofabrication --- articular cartilage --- human chondrocytes --- cell density --- cell gradient --- 3D bioprinting --- ChondroMimetic --- cartilage regeneration --- osteochondral repair --- matrix-assisted autologous chondrocyte transplantation --- magneto-responsive techniques --- biomechanical stimuli --- multi-disciplinary approach

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• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Advances in Nanomaterials in Biomedicine” provided a platform for more than 110 researchers from different countries to present their latest investigations in various fields of nanotechnology, new methods and nanomaterials intended for medical applications. Modern achievements in the field of nanoparticle-based diagnostics, drug delivery and the use of various nanomaterials in the treatment of diseases are presented in 11 original articles. The published reviews provide a comprehensive analysis of the current information on the use of nanomedicine in the treatment and diagnosis of cancer and liver fibrosis, in the field of solid tissue engineering and in drug delivery systems.

Medicine --- bone marrow-derived mesenchymal stromal cells --- rAAV vectors --- carbon dots --- SOX9 --- TGF-β --- cartilage repair --- silver nanoparticles --- Entada spiralis --- Ceiba pentandra --- antibacterial assay --- catalytic dye reduction --- osteoarthritis --- human articular cartilage --- polymeric micelles --- pro-inflammatory cytokines --- IL-1β --- TNF-α --- nanomaterials --- nanomedicine --- immunotherapy --- oncotherapy --- immune-checkpoint inhibitors --- immunogenic cell death --- nano-vaccines --- nano-conjugates --- immune response --- oxidative stress --- antioxidants --- nanoparticles --- biological nano-antioxidants --- gold nanoparticles --- radiation --- chemotherapy --- radiosensitizer --- drug delivery system --- chemoradiotherapy --- magnetoliposomes --- hydrogels --- magnetolipogels --- self-assembly --- fluorescence --- Förster resonance energy transfer --- polypropylenimine dendrimers --- polyethylenimines --- tyrosine-modified polypropylene-imines --- tyrosine-modified polyethlyenimines --- PPI-Y --- siRNA transfection --- polymeric nanoparticles --- carbosilane --- dendron --- triazine --- amphiphile --- vesicles --- pH-sensitive --- doxorubicin --- methotrexate --- leukaemia --- molecular ultrasound --- nanobubbles --- active targeting --- targeted microbubbles --- angiogenesis --- inflammation --- thrombosis --- clinical translation --- molecular imaging --- liver fibrosis --- diagnosis --- therapy --- theranostics --- targeted drug delivery --- lipid conjugates --- amphiphilic oligonucleotides --- phosphoryl guanidines --- nucleic acid delivery --- leukemia --- iron nanoparticles --- RNA-Seq --- cytotoxicity --- polymers --- biodegradable --- drug delivery --- pharmaceutical --- SQUID --- magnetic properties --- iron content --- magnetite nanoparticles --- superoxide --- aorta --- heart --- nano-biomaterials --- nanotechnology --- scaffolds --- hard tissue engineering --- AuNPs --- AuPEI-NPs --- AuBSA-NPs --- electron microscopy --- ultrastructure of HepG2 cells and spheroids --- ultrastructure of HEK293 cells and spheroids --- penetration of NPs into monolayer and spheroids --- gold nanostars --- photothermal therapy --- photoacoustic imaging --- computed tomography --- cancer --- theranostic agents --- biocompatible nanomaterials --- diagnostics --- nanocarriers --- tissue engineering --- bone marrow-derived mesenchymal stromal cells --- rAAV vectors --- carbon dots --- SOX9 --- TGF-β --- cartilage repair --- silver nanoparticles --- Entada spiralis --- Ceiba pentandra --- antibacterial assay --- catalytic dye reduction --- osteoarthritis --- human articular cartilage --- polymeric micelles --- pro-inflammatory cytokines --- IL-1β --- TNF-α --- nanomaterials --- nanomedicine --- immunotherapy --- oncotherapy --- immune-checkpoint inhibitors --- immunogenic cell death --- nano-vaccines --- nano-conjugates --- immune response --- oxidative stress --- antioxidants --- nanoparticles --- biological nano-antioxidants --- gold nanoparticles --- radiation --- chemotherapy --- radiosensitizer --- drug delivery system --- chemoradiotherapy --- magnetoliposomes --- hydrogels --- magnetolipogels --- self-assembly --- fluorescence --- Förster resonance energy transfer --- polypropylenimine dendrimers --- polyethylenimines --- tyrosine-modified polypropylene-imines --- tyrosine-modified polyethlyenimines --- PPI-Y --- siRNA transfection --- polymeric nanoparticles --- carbosilane --- dendron --- triazine --- amphiphile --- vesicles --- pH-sensitive --- doxorubicin --- methotrexate --- leukaemia --- molecular ultrasound --- nanobubbles --- active targeting --- targeted microbubbles --- angiogenesis --- inflammation --- thrombosis --- clinical translation --- molecular imaging --- liver fibrosis --- diagnosis --- therapy --- theranostics --- targeted drug delivery --- lipid conjugates --- amphiphilic oligonucleotides --- phosphoryl guanidines --- nucleic acid delivery --- leukemia --- iron nanoparticles --- RNA-Seq --- cytotoxicity --- polymers --- biodegradable --- drug delivery --- pharmaceutical --- SQUID --- magnetic properties --- iron content --- magnetite nanoparticles --- superoxide --- aorta --- heart --- nano-biomaterials --- nanotechnology --- scaffolds --- hard tissue engineering --- AuNPs --- AuPEI-NPs --- AuBSA-NPs --- electron microscopy --- ultrastructure of HepG2 cells and spheroids --- ultrastructure of HEK293 cells and spheroids --- penetration of NPs into monolayer and spheroids --- gold nanostars --- photothermal therapy --- photoacoustic imaging --- computed tomography --- cancer --- theranostic agents --- biocompatible nanomaterials --- diagnostics --- nanocarriers --- tissue engineering