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Book
Adipokines 2.0
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ISBN: 3039285874 3039285866 Year: 2020 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

Once viewed solely as fat storage cells, adipocytes and their adipokines have now been proven to be central for human health. Understanding that overweight and obesity may increase the risk for various diseases requires detailed characterization of adipokine function. Weight gain, weight regain, and fasting affect adipocyte health and accordingly their secretome. Different adipose tissue deposits exist and they vary in cellular composition and function. The evidence is strong of a role of adipokines in cancer, reproductive function, neurological diseases, cardiovascular diseases ,and rheumatoid arthritis. Adipokines are considered useful biomarkers for adipose tissue and metabolic health, and may be used as diagnostic tools in rheumatoid arthritis, cancer, or sepsis. This book contains 10 original articles and 9 review articles focusing on these bioactive peptides. Several articles deal with chemerin, an adipokine discovered more than 20 years ago. Data so far have resulted in promising insights related to its biological function. We are only beginning to understand the multiple roles of chemerin, the mechanisms regulating its activity, and the signaling pathways used by this chemokine. Adipokine receptor agonists and antagonists may result in the formulation of novel drugs and ultimately may lead to new therapeutic targets to be used in clinical practice.

Keywords

n/a --- lipids --- cathepsins --- neurodegeneration --- tocilizumab --- SGBS adipocytes --- chemerin receptors --- cholesterol --- metabolically healthy obese --- energy metabolism --- adipose-brain axis --- EP3 receptor --- leptin --- rheumatoid arthritis --- excessive gestational weight gain --- in vitro fat regain --- secreted frizzled-related protein 5 --- PCOS --- EP4 receptor --- leukocyte --- exchange protein directly activated by cAMP isoform 2 (EPAC2) --- extracellular remodeling --- insulin --- osteoarthritis --- lipid metabolism --- fat mass --- Tango bioassay --- fatty liver --- free fatty acids --- label-free proteomic profiling --- interleukin(IL)-33 --- sick fat --- polycystic ovary syndrome --- early-life programming --- inflammation --- gestational diabetes --- glucose restriction --- adipokines --- neonatal anthropometry --- epicardial adipose tissue (EAT) --- oestrous cycle --- Cardiovascular Diseases (CVDs) --- triglycerides --- G protein-coupled receptor 1 --- testicular pathologies --- prognosis --- ovary --- ICU --- biologic activity --- preeclempsia --- adipokine --- critical illness --- early pregnancy --- myokine --- liver steatosis --- C-C chemokine receptor-like 2 --- testis --- stimulating growth factor 2 (ST2) --- pig --- fitness --- human granulosa cells --- obesity --- proteolysis --- annexins --- adipose tissue --- biomarker --- ghrelin --- brain health --- sepsis --- adiponectin --- rheumatic diseases --- chemokine-like receptor 1 --- follicular fluid --- glucose homeostasis --- resistin --- Nonalcoholic fatty liver disease --- prostaglandin E2 (PGE2) --- visceral fat --- microglia --- weight regain --- complement factors --- alpha-fetoprotein --- polycystic ovary morphology --- chemerin --- cancer --- depression --- hypertension --- hypothalamus


Book
Environmental Analysis of Organic Pollutants
Author:
ISBN: 3036553169 3036553150 Year: 2022 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

In recent decades, the environmental impact of organic pollutants, especially persistent and emerging organic pollutants, has attracted widespread attention, and related research has been rapidly developed. Organic pollutants represent a popular topic of research in the environmental field. Large amounts of organic pollutants, which are widely distributed in air, water, sediment, soil, and other environmental media, are created via industrial production and other human activities. A series of research projects have been carried out regarding the development of analytical methods for organic pollutants, the distribution of environmental media, environmental concentration, environmental fate, the exploration of new pollutants, and the non-target analysis of organic pollutants.

Keywords

Technology: general issues --- Chemical engineering --- regulated e-waste recycling --- polybrominated diphenyl ethers (PBDEs) --- heavy metals --- environmental media --- vegetable --- risks --- cardiovascular diseases (CVDs) --- heart failure --- polycyclic aromatic hydrocarbons (PAHs) --- trace elements --- serum --- polyhaloaromatic compounds --- chemiluminescence --- analytical method --- Fenton system --- hydroxyl radicals --- bisphenol analogues --- zebrafish --- joint toxicity --- gene expression --- online monitoring --- diagnosis --- PCDD/F --- incineration --- feedback control --- volatile organic compounds (VOCs) --- reference materials (RMs) --- quality control (QC) --- water analysis --- resin --- adsorption --- pore size distribution --- chemical modification --- water treatment --- PCNs --- spatial distribution --- congener --- environmental risk --- sediment --- VOCs --- distribution --- risk assessment --- chemical industrial park --- phthalate --- dietary intake --- DEHP --- DBP --- DIBP --- bottled drink --- PFASs --- QSAR–ICE–SSD --- electroplating industry --- ecological risk assessment --- PAHs --- historical trends --- shallow lake --- economic parameters --- sources --- sediment core --- gas chromatography-mass spectrometry --- HBCD --- EPS --- XPS --- POPs --- tetrabromobisphenol A --- Xenopus laevis --- brain development --- thyroid hormone --- biphasic concentration-response --- composting --- turning frequency --- ammonia oxidizing bacterial --- ammonia oxidizing archaeal --- N fractions --- ammonia emission --- screening assay --- thibz gene --- multiwell plate --- biomass combustion --- CHP plant --- renewable energies --- emission --- organic pollutants --- bisphenol analogs --- oxidative stress --- dechlorane plus --- maternal blood --- sequential samples --- variation --- correlation --- bisphenol A --- emissions --- polypropylene --- bottom sediments --- environmental monitoring --- Odra River estuary --- organotin compounds --- trueness --- verification

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