Listing 1 - 5 of 5 |
Sort by
|
Choose an application
Cancer gene therapy is a novel therapy that targets the underlying genetic defects in the cancer cell. Progress in this field has been rapid and gene therapy promises to further extend personalized cancer treatment. In this volume leading experts have contributed their experience in developing gene therapies for a variety of cancers. Translational gene therapy approaches are emphasized. Chapters include discussions of specific gene delivery technologies as well as their application to various cancers with extensive discussions of ongoing clinical trials. This information should be useful to students, fellows, clinical investigators, and experienced scientists with an interest in this rapidly developing area.
Cancer -- Gene therapy. --- Gene therapy. --- Neoplasms -- Therapy. --- Cancer --- Methods --- Gene Therapy --- Neoplasms --- Diseases --- Genetic Engineering --- Biological Therapy --- Investigative Techniques --- Genetic Techniques --- Therapeutics --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Oncology --- Medicine --- Health & Biological Sciences --- Gene therapy --- Medicine. --- Cancer research. --- Pharmacology. --- Biomedicine. --- Cancer Research. --- Pharmacology/Toxicology. --- Genetic aspects --- Treatment --- Oncology. --- Toxicology. --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Tumors --- Toxicology --- Drug effects --- Medical pharmacology --- Medical sciences --- Chemotherapy --- Drugs --- Pharmacy --- Cancer research --- Physiological effect
Choose an application
Viruses are microscopic agents that exist worldwide and are present in humans, animals, plants, and other living organisms in which they can cause devastating diseases. However, the advances of biotechnology and next-generation sequencing technologies have accelerated novel virus discovery, identification, sequencing, and manipulation, showing that they present unique characteristics that place them as valuable tools for a wide variety of biotechnological applications. Many applications of viruses have been used for agricultural purposes, namely concerning plant breeding and plant protection. Nevertheless, it is interesting to mention that plants have also many advantages to be used in vaccine production, such as the low cost and low risks they entail, showing once more the versatility of the use of viruses in biotechnology. Although it will obviously never be ignored that viruses are responsible for devastating diseases, it is clear that the more they are studied, the more possibilities they offer to us. They are now on the front line of the most revolutionizing techniques in several fields, providing advances that would not be possible without their existence. In this book there are presented studies that demonstrate the work developed using viruses in biotechnology. These studies were brought by experts that focus on the development and applications of many viruses in several fields, such as agriculture, the pharmaceutical industry, and medicine.
Technology: general issues --- Bacteriophage --- Salmonella --- biocontrol --- comparative genomics --- phage diversity --- grapevine --- apple latent spherical virus vector --- virus-induced flowering --- reduced generation time --- breeding of grapevine --- virus elimination --- Newcastle disease virus --- reverse genetics --- vaccines --- infectious diseases --- cancer --- porcine epidemic diarrhea virus --- VLP --- chemokines --- pig --- vaccine --- SARS-CoV-2 --- COVID-19 --- phages --- CRISPR --- viruses --- prevention --- diagnosis --- treatment --- adeno-associated virus (AAV) vector --- jaagsiekte sheep retrovirus (JSRV) --- LTR --- enhancer --- transduction --- viral vaccines --- cancers --- COVID-19 vaccines --- self-replicating RNA vectors --- DNA-based vaccines --- RNA-based vaccines --- plant virus --- viroid --- viral vector --- virus-induced gene silencing (VIGS) --- CRISPR/Cas9 --- genome editing --- carotenoid biosynthesis --- circular RNA --- infectious bursal disease virus --- immunization --- recombinant Lactococcus lactis --- variant strain --- baculovirus --- insect cells --- bacmid --- Tn7 --- genome stability --- protein expression --- chikungunya virus --- VLPs --- bioreactor --- CRISPR/Cas systems --- viral vectors --- gene editing --- plant genome engineering --- viral resistance --- adeno-associated virus --- AAV --- cancer gene therapy --- prophage --- hydrothermal vent --- Hypnocyclicus thermotrophus --- lytic cassette --- Escherichia coli --- heterologous expression --- codon optimization --- codon harmonization --- expression vectors --- aspect ratio --- VNPs --- TMV --- PVX --- CPMV --- geminivirus --- theranostics --- CRISPR-cas9 --- clodronate --- macrophage --- gene therapy --- gene expression --- nanotechnology --- Bacteriophage --- Salmonella --- biocontrol --- comparative genomics --- phage diversity --- grapevine --- apple latent spherical virus vector --- virus-induced flowering --- reduced generation time --- breeding of grapevine --- virus elimination --- Newcastle disease virus --- reverse genetics --- vaccines --- infectious diseases --- cancer --- porcine epidemic diarrhea virus --- VLP --- chemokines --- pig --- vaccine --- SARS-CoV-2 --- COVID-19 --- phages --- CRISPR --- viruses --- prevention --- diagnosis --- treatment --- adeno-associated virus (AAV) vector --- jaagsiekte sheep retrovirus (JSRV) --- LTR --- enhancer --- transduction --- viral vaccines --- cancers --- COVID-19 vaccines --- self-replicating RNA vectors --- DNA-based vaccines --- RNA-based vaccines --- plant virus --- viroid --- viral vector --- virus-induced gene silencing (VIGS) --- CRISPR/Cas9 --- genome editing --- carotenoid biosynthesis --- circular RNA --- infectious bursal disease virus --- immunization --- recombinant Lactococcus lactis --- variant strain --- baculovirus --- insect cells --- bacmid --- Tn7 --- genome stability --- protein expression --- chikungunya virus --- VLPs --- bioreactor --- CRISPR/Cas systems --- viral vectors --- gene editing --- plant genome engineering --- viral resistance --- adeno-associated virus --- AAV --- cancer gene therapy --- prophage --- hydrothermal vent --- Hypnocyclicus thermotrophus --- lytic cassette --- Escherichia coli --- heterologous expression --- codon optimization --- codon harmonization --- expression vectors --- aspect ratio --- VNPs --- TMV --- PVX --- CPMV --- geminivirus --- theranostics --- CRISPR-cas9 --- clodronate --- macrophage --- gene therapy --- gene expression --- nanotechnology
Choose an application
Growth factor receptors have long been known to drive malignant transformation and cancer progression. The epidermal growth factor receptor (EGFR, ErbB, HER) system is likely the best described membrane receptor tyrosine kinase family in malignant tumors. With implementation of the growth-inhibitory anti-HER-2 antibody trastuzumab (Herceptin) for the treatment of HER-2-positive advanced metastatic breast cancer, a new era has dawned in the therapy of this malignant disease. Unfortunately, trastuzumab-sensitive cancers invariably develop resistance to the antibody after some time. Recent clinical studies have revealed that these refractory tumors are still responsive to inhibition of the HER receptor family using dual HER-1/-2 inhibitors such as lapatinib (Tykerb/Tyverb). Moreover, a multiplicity of novel, improved irreversibly acting small molecular HER tyrosine kinase inhibitors are in the pipeline of many drug developing companies and are being evaluated in the clinical setting.
BRCA genes. --- Breast -- Cancer -- Chemotherapy. --- Cancer -- Gene therapy. --- Trastuzumab. --- Trastuzumab --- BRCA genes --- Cancer --- Breast --- Antibodies --- Neoplasms by Site --- Genes, erbB --- Therapeutics --- Investigative Techniques --- Breast Diseases --- Biological Science Disciplines --- Therapeutic Uses --- Natural Science Disciplines --- Skin Diseases --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Pharmacologic Actions --- Neoplasms --- Immunoglobulins --- Proto-Oncogenes --- Skin and Connective Tissue Diseases --- Immunoproteins --- Diseases --- Oncogenes --- Serum Globulins --- Chemical Actions and Uses --- Disciplines and Occupations --- Genes, Neoplasm --- Blood Proteins --- Chemicals and Drugs --- Globulins --- Proteins --- Genes --- Methods --- Antibodies, Monoclonal --- Breast Neoplasms --- Genes, erbB-2 --- Antineoplastic Agents --- Molecular Targeted Therapy --- Drug Therapy --- Pharmacology --- Amino Acids, Peptides, and Proteins --- Genome Components --- Genome --- Genetic Structures --- Genetic Phenomena --- Phenomena and Processes --- Medicine --- Health & Biological Sciences --- Oncology --- Pharmacy, Therapeutics, & Pharmacology --- Gene therapy --- Chemotherapy --- Cancer. --- Treatment. --- Cancer therapy --- Cancer treatment --- Therapy --- Medicine. --- Cancer research. --- Immunology. --- Antibodies. --- Pharmacology. --- Internal medicine. --- Oncology. --- Biomedicine. --- Pharmacology/Toxicology. --- Cancer Research. --- Internal Medicine. --- Toxicology. --- Oncology . --- Monoclonal antibodies. --- Medicine, Internal --- Immunobiology --- Life sciences --- Serology --- Monoclonal immunoglobulins --- Molecular cloning --- Tumors --- Chemicals --- Poisoning --- Poisons --- Toxicology --- Immune globulins --- Immune serum globulin --- Blood proteins --- Plasma cells --- Antibody diversity --- Antigens --- Bacterial immunoglobulin-binding proteins --- Cancer research --- Drug effects --- Medical pharmacology --- Medical sciences --- Drugs --- Pharmacy --- Physiological effect
Choose an application
Viruses are microscopic agents that exist worldwide and are present in humans, animals, plants, and other living organisms in which they can cause devastating diseases. However, the advances of biotechnology and next-generation sequencing technologies have accelerated novel virus discovery, identification, sequencing, and manipulation, showing that they present unique characteristics that place them as valuable tools for a wide variety of biotechnological applications. Many applications of viruses have been used for agricultural purposes, namely concerning plant breeding and plant protection. Nevertheless, it is interesting to mention that plants have also many advantages to be used in vaccine production, such as the low cost and low risks they entail, showing once more the versatility of the use of viruses in biotechnology. Although it will obviously never be ignored that viruses are responsible for devastating diseases, it is clear that the more they are studied, the more possibilities they offer to us. They are now on the front line of the most revolutionizing techniques in several fields, providing advances that would not be possible without their existence. In this book there are presented studies that demonstrate the work developed using viruses in biotechnology. These studies were brought by experts that focus on the development and applications of many viruses in several fields, such as agriculture, the pharmaceutical industry, and medicine.
Technology: general issues --- Bacteriophage --- Salmonella --- biocontrol --- comparative genomics --- phage diversity --- grapevine --- apple latent spherical virus vector --- virus-induced flowering --- reduced generation time --- breeding of grapevine --- virus elimination --- Newcastle disease virus --- reverse genetics --- vaccines --- infectious diseases --- cancer --- porcine epidemic diarrhea virus --- VLP --- chemokines --- pig --- vaccine --- SARS-CoV-2 --- COVID-19 --- phages --- CRISPR --- viruses --- prevention --- diagnosis --- treatment --- adeno-associated virus (AAV) vector --- jaagsiekte sheep retrovirus (JSRV) --- LTR --- enhancer --- transduction --- viral vaccines --- cancers --- COVID-19 vaccines --- self-replicating RNA vectors --- DNA-based vaccines --- RNA-based vaccines --- plant virus --- viroid --- viral vector --- virus-induced gene silencing (VIGS) --- CRISPR/Cas9 --- genome editing --- carotenoid biosynthesis --- circular RNA --- infectious bursal disease virus --- immunization --- recombinant Lactococcus lactis --- variant strain --- baculovirus --- insect cells --- bacmid --- Tn7 --- genome stability --- protein expression --- chikungunya virus --- VLPs --- bioreactor --- CRISPR/Cas systems --- viral vectors --- gene editing --- plant genome engineering --- viral resistance --- adeno-associated virus --- AAV --- cancer gene therapy --- prophage --- hydrothermal vent --- Hypnocyclicus thermotrophus --- lytic cassette --- Escherichia coli --- heterologous expression --- codon optimization --- codon harmonization --- expression vectors --- aspect ratio --- VNPs --- TMV --- PVX --- CPMV --- geminivirus --- theranostics --- CRISPR-cas9 --- clodronate --- macrophage --- gene therapy --- gene expression --- nanotechnology
Choose an application
Viruses are microscopic agents that exist worldwide and are present in humans, animals, plants, and other living organisms in which they can cause devastating diseases. However, the advances of biotechnology and next-generation sequencing technologies have accelerated novel virus discovery, identification, sequencing, and manipulation, showing that they present unique characteristics that place them as valuable tools for a wide variety of biotechnological applications. Many applications of viruses have been used for agricultural purposes, namely concerning plant breeding and plant protection. Nevertheless, it is interesting to mention that plants have also many advantages to be used in vaccine production, such as the low cost and low risks they entail, showing once more the versatility of the use of viruses in biotechnology. Although it will obviously never be ignored that viruses are responsible for devastating diseases, it is clear that the more they are studied, the more possibilities they offer to us. They are now on the front line of the most revolutionizing techniques in several fields, providing advances that would not be possible without their existence. In this book there are presented studies that demonstrate the work developed using viruses in biotechnology. These studies were brought by experts that focus on the development and applications of many viruses in several fields, such as agriculture, the pharmaceutical industry, and medicine.
Bacteriophage --- Salmonella --- biocontrol --- comparative genomics --- phage diversity --- grapevine --- apple latent spherical virus vector --- virus-induced flowering --- reduced generation time --- breeding of grapevine --- virus elimination --- Newcastle disease virus --- reverse genetics --- vaccines --- infectious diseases --- cancer --- porcine epidemic diarrhea virus --- VLP --- chemokines --- pig --- vaccine --- SARS-CoV-2 --- COVID-19 --- phages --- CRISPR --- viruses --- prevention --- diagnosis --- treatment --- adeno-associated virus (AAV) vector --- jaagsiekte sheep retrovirus (JSRV) --- LTR --- enhancer --- transduction --- viral vaccines --- cancers --- COVID-19 vaccines --- self-replicating RNA vectors --- DNA-based vaccines --- RNA-based vaccines --- plant virus --- viroid --- viral vector --- virus-induced gene silencing (VIGS) --- CRISPR/Cas9 --- genome editing --- carotenoid biosynthesis --- circular RNA --- infectious bursal disease virus --- immunization --- recombinant Lactococcus lactis --- variant strain --- baculovirus --- insect cells --- bacmid --- Tn7 --- genome stability --- protein expression --- chikungunya virus --- VLPs --- bioreactor --- CRISPR/Cas systems --- viral vectors --- gene editing --- plant genome engineering --- viral resistance --- adeno-associated virus --- AAV --- cancer gene therapy --- prophage --- hydrothermal vent --- Hypnocyclicus thermotrophus --- lytic cassette --- Escherichia coli --- heterologous expression --- codon optimization --- codon harmonization --- expression vectors --- aspect ratio --- VNPs --- TMV --- PVX --- CPMV --- geminivirus --- theranostics --- CRISPR-cas9 --- clodronate --- macrophage --- gene therapy --- gene expression --- nanotechnology
Listing 1 - 5 of 5 |
Sort by
|