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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Civil engineering, surveying & building --- Biotechnology --- Synthetic Biology --- Metabolic Engineering --- Genetic constructs --- Bioproduction --- TX-TL --- Synthetic Biology --- Metabolic Engineering --- Genetic constructs --- Bioproduction --- TX-TL

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The production of industrial and bioenergy crops has been the subject of scientific research for many years; however, the implementation of previously proposed solutions for commercial production is still at an early stage. It should be emphasized that when developing the production of industrial and bioenergy crops on agricultural lands, it is important to avoid land-use competition with the production of food and feed. It is well justified, for initiating the sustainable production of industrial and bioenergy crops, to promote efficient species for growing on marginal lands, which are unsuitable or less suitable for food or feed production. Another important point is that industrial and bioenergy crops should include nonfood and nonfeed crops and generate agricultural products categorized as commodities and/or raw materials for industrial goods and bioenergy. These industrial and bioenergy crops can become an important source of biomass. Of course, the concept of their cultivation for nonfood (and/or nonfeed) uses is not new but, despite considerable investment in research and development, little progress has been made with regard to the introduction of such crops and their products into the market. Therefore, the papers focus on innovations and perspectives regarding sustainable industrial and bioenergy crops production, logistic chains, biomass quality, utilization and cascade biomass use for bioeconomy, socio-economic and energy analyses, etc.

Technology: general issues --- History of engineering & technology --- harvesting --- work productivity --- supply chain --- harvesting efficiency --- Salix --- genoype × site interaction --- survivability --- biometric features --- plant height --- fresh biomass yield --- dry biomass yield --- Miscanthus --- nitrogen fertilization --- rhizomes --- stem --- leaves --- consumer choices --- eucalyptus --- firewood --- Italy --- multilevel logistic regression model --- willingness to consume --- tobacco biomass --- energy yield --- higher heating value --- biogas potential --- Nicotiana tabacum --- energy crops --- planting density --- calorific value --- SRC --- hulled wheat species --- energy --- life cycle assessment --- Tenebrio molitor --- edible insects --- larval development --- feed conversion ratio --- agricultural and industrial residues --- lignocellulosic biomass --- bioconversion --- agroforestry --- biodiversity --- bioeconomy --- biomass supply --- circular economy --- organic farming --- perennial crops --- quarry --- syntropy --- vegetation restoration --- willow --- varieties --- yield --- marginal soil --- biological diversity --- marginal land --- cup plant --- perennial energy crop --- energy expenses --- biogas --- biomass yield --- willow SRC --- energy plants --- ground beetles --- Carabidae --- ecosystem services --- invertebrate biodiversity --- willow-leaf sunflower --- Jerusalem artichoke --- supercritical extraction --- water as co-solvent --- antimicrobial activity --- biocidal effect --- bioenergy crop --- groundwater --- growth --- invasive potential --- reproductive potential --- Silphium perfoliatum --- soil moisture --- water table distance --- energy biomass --- yields --- invasive behavior --- economics --- common osier --- fertilization --- dry matter yield --- soil chemical parameters --- soil bulk density --- water-stable aggregates --- soil microbial carbon --- willow browse --- soluble carbohydrates --- browsing damage --- cervids --- gas chromatography --- aboveground --- belowground part of Miscanthus × giganteus --- ash --- potassium --- calcium --- sulphur content --- uptake --- bioproduction --- CAP payments --- sustainable agriculture --- Poland --- unutilized agricultural areas (uUAA) --- abandoned areas --- land use and land-use change --- carbon sequestration --- soil properties (physical and chemical) --- polyphenols --- supercritical CO2 extraction --- perennial industrial crops --- antioxidant activity --- silvergrass --- willowleaf sunflower --- prairie cordgrass --- n/a

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The production of industrial and bioenergy crops has been the subject of scientific research for many years; however, the implementation of previously proposed solutions for commercial production is still at an early stage. It should be emphasized that when developing the production of industrial and bioenergy crops on agricultural lands, it is important to avoid land-use competition with the production of food and feed. It is well justified, for initiating the sustainable production of industrial and bioenergy crops, to promote efficient species for growing on marginal lands, which are unsuitable or less suitable for food or feed production. Another important point is that industrial and bioenergy crops should include nonfood and nonfeed crops and generate agricultural products categorized as commodities and/or raw materials for industrial goods and bioenergy. These industrial and bioenergy crops can become an important source of biomass. Of course, the concept of their cultivation for nonfood (and/or nonfeed) uses is not new but, despite considerable investment in research and development, little progress has been made with regard to the introduction of such crops and their products into the market. Therefore, the papers focus on innovations and perspectives regarding sustainable industrial and bioenergy crops production, logistic chains, biomass quality, utilization and cascade biomass use for bioeconomy, socio-economic and energy analyses, etc.

Technology: general issues --- History of engineering & technology --- harvesting --- work productivity --- supply chain --- harvesting efficiency --- Salix --- genoype × site interaction --- survivability --- biometric features --- plant height --- fresh biomass yield --- dry biomass yield --- Miscanthus --- nitrogen fertilization --- rhizomes --- stem --- leaves --- consumer choices --- eucalyptus --- firewood --- Italy --- multilevel logistic regression model --- willingness to consume --- tobacco biomass --- energy yield --- higher heating value --- biogas potential --- Nicotiana tabacum --- energy crops --- planting density --- calorific value --- SRC --- hulled wheat species --- energy --- life cycle assessment --- Tenebrio molitor --- edible insects --- larval development --- feed conversion ratio --- agricultural and industrial residues --- lignocellulosic biomass --- bioconversion --- agroforestry --- biodiversity --- bioeconomy --- biomass supply --- circular economy --- organic farming --- perennial crops --- quarry --- syntropy --- vegetation restoration --- willow --- varieties --- yield --- marginal soil --- biological diversity --- marginal land --- cup plant --- perennial energy crop --- energy expenses --- biogas --- biomass yield --- willow SRC --- energy plants --- ground beetles --- Carabidae --- ecosystem services --- invertebrate biodiversity --- willow-leaf sunflower --- Jerusalem artichoke --- supercritical extraction --- water as co-solvent --- antimicrobial activity --- biocidal effect --- bioenergy crop --- groundwater --- growth --- invasive potential --- reproductive potential --- Silphium perfoliatum --- soil moisture --- water table distance --- energy biomass --- yields --- invasive behavior --- economics --- common osier --- fertilization --- dry matter yield --- soil chemical parameters --- soil bulk density --- water-stable aggregates --- soil microbial carbon --- willow browse --- soluble carbohydrates --- browsing damage --- cervids --- gas chromatography --- aboveground --- belowground part of Miscanthus × giganteus --- ash --- potassium --- calcium --- sulphur content --- uptake --- bioproduction --- CAP payments --- sustainable agriculture --- Poland --- unutilized agricultural areas (uUAA) --- abandoned areas --- land use and land-use change --- carbon sequestration --- soil properties (physical and chemical) --- polyphenols --- supercritical CO2 extraction --- perennial industrial crops --- antioxidant activity --- silvergrass --- willowleaf sunflower --- prairie cordgrass --- harvesting --- work productivity --- supply chain --- harvesting efficiency --- Salix --- genoype × site interaction --- survivability --- biometric features --- plant height --- fresh biomass yield --- dry biomass yield --- Miscanthus --- nitrogen fertilization --- rhizomes --- stem --- leaves --- consumer choices --- eucalyptus --- firewood --- Italy --- multilevel logistic regression model --- willingness to consume --- tobacco biomass --- energy yield --- higher heating value --- biogas potential --- Nicotiana tabacum --- energy crops --- planting density --- calorific value --- SRC --- hulled wheat species --- energy --- life cycle assessment --- Tenebrio molitor --- edible insects --- larval development --- feed conversion ratio --- agricultural and industrial residues --- lignocellulosic biomass --- bioconversion --- agroforestry --- biodiversity --- bioeconomy --- biomass supply --- circular economy --- organic farming --- perennial crops --- quarry --- syntropy --- vegetation restoration --- willow --- varieties --- yield --- marginal soil --- biological diversity --- marginal land --- cup plant --- perennial energy crop --- energy expenses --- biogas --- biomass yield --- willow SRC --- energy plants --- ground beetles --- Carabidae --- ecosystem services --- invertebrate biodiversity --- willow-leaf sunflower --- Jerusalem artichoke --- supercritical extraction --- water as co-solvent --- antimicrobial activity --- biocidal effect --- bioenergy crop --- groundwater --- growth --- invasive potential --- reproductive potential --- Silphium perfoliatum --- soil moisture --- water table distance --- energy biomass --- yields --- invasive behavior --- economics --- common osier --- fertilization --- dry matter yield --- soil chemical parameters --- soil bulk density --- water-stable aggregates --- soil microbial carbon --- willow browse --- soluble carbohydrates --- browsing damage --- cervids --- gas chromatography --- aboveground --- belowground part of Miscanthus × giganteus --- ash --- potassium --- calcium --- sulphur content --- uptake --- bioproduction --- CAP payments --- sustainable agriculture --- Poland --- unutilized agricultural areas (uUAA) --- abandoned areas --- land use and land-use change --- carbon sequestration --- soil properties (physical and chemical) --- polyphenols --- supercritical CO2 extraction --- perennial industrial crops --- antioxidant activity --- silvergrass --- willowleaf sunflower --- prairie cordgrass

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Many research teams are working to demonstrate that microorganisms can be our daily partners, due to the great diversity of biochemical transformations and molecules they are able to produce. This Special Issue highlights several facets of the production of microbial metabolites of interest. From the discovery of new strains or new bioactive molecules issued from novel environments, to the increase in their synthesis by traditional or innovative methods, different levels of biotechnological processes are addressed. Combining the new dimensions of "Omics" sciences, such as genomics, transcriptomics or metabolomics, microbial biotechnologies are opening up incredible opportunities for discovering and improving microorganisms and their production.

Research & information: general --- Biology, life sciences --- Microbiology (non-medical) --- Docosahexaenoic acid (DHA) --- polyunsaturated fatty acids (PUFAs) --- mutant strain --- Aurantiochytrium sp. --- transcriptome --- Xanthomonas campestris pv. campestris --- 6-pentyl-α-pyrone --- antibiosis --- Trichoderma --- secondary metabolites --- antibiofilm --- Gram-negative bacterium --- antibiotic resistance --- natural products --- angucycline --- aquayamycin --- glycosyltransferase --- Lake Baikal --- Streptomyces --- Talaromyces albobiverticillius 30548 --- submerged fermentation --- pigments --- biomass --- optimization --- Box–Behnken experimental design --- response surface modeling --- carnosic acid --- propolis --- antifungal action --- synergy --- Candida albicans --- biofilms --- sponges --- actinomycetes --- cryptic --- Micromonospora --- Nocardia --- Gordonia --- mycolic acid --- LC-HRESIMS --- N-functionalized amines --- N-methylanthranilate --- Corynebacterium glutamicum --- metabolic engineering --- sustainable production of quinoline precursors --- acridone --- quinazoline alkaloid drugs --- SARS-CoV-2 --- Covid-19 --- Mpro --- microbial natural products --- docking --- molecular dynamic simulation --- Serratiochelin A --- Serratiochelin C --- Serratia sp. --- siderophore --- iron --- anticancer --- microbial biotechnology --- degradation --- antibacterial --- S. aureus --- sparkling wine --- second fermentation --- fermentation by-products --- Saccharomyces cerevisiae flor yeast --- proteins --- Scopalina hapalia --- Actinomycetes --- Bacillus --- Fungi --- elastase inhibition --- tyrosinase inhibition --- CDK7 inhibition --- Fyn kinase inhibition --- catalase activation --- sirtuin 1 activation --- Curvularia papendorfii --- endophytic fungi --- human coronavirus HCoV 229E --- Staphylococcus sp. --- MRSA --- antiproliferative activity --- polyhydroxyacid --- kheiric acid --- insect --- mealworm --- gut bacteria --- OSMAC --- cyclic peptides --- biosynthetic pathway --- autophagy inducer --- fermentation --- Lactococcus lactis --- bacteriocin --- culture conditions --- medium compositions --- lactic acid fermentation --- Pediococcus acidilactici PA204 --- simultaneous saccharification and fermentation --- corn stover --- pyocyanin --- maize industry wastewater --- Pseudomonas aeruginosa NEJ01R --- redox metabolite --- response surface analysis --- bioproduction --- valorization --- electrochemical analysis --- sugarcane --- distillery waste water --- molasses spent wash --- vinasse --- fungi --- yeasts --- bioremediation --- COD --- discoloration --- antimicrobial --- antioxidant --- GNPS --- textiles --- cation-exchange resin --- adsorption --- removal --- ammonium --- cell viability --- mutant gdhA P. multocida B:2 --- cyanobacteria --- photosynthesis --- synthetic biology --- systems biology --- genome-scale model --- protoplast fusion --- novel compound discovery --- cell wall-deficiency --- heteroploidy --- Talaromyces --- azaphilone --- marine fungi --- N-threonyl-rubropunctamin --- PP-R --- greener extraction --- red pigments --- fungal pigments --- antinematode compound --- anthelminthic drugs --- marine epiphytic bacteria --- marine biofilm --- marine environment --- parasitic nematode --- Caenorhabditis elegans --- natural colors --- bio-pigments --- quorum sensing --- marine bacteria --- biosynthesis --- biological activities --- industrial applications --- therapeutic insights --- global pigment market --- terpenoids --- sesquiterpene production --- Rhodobacter capsulatus --- β-caryophyllene --- bioactivity --- phytopathogens --- plant pathogenic fungi --- plant growth-promoting bacteria --- microorganisms --- biotechnology --- screening --- production --- extraction --- bioactive properties --- perspectives --- Docosahexaenoic acid (DHA) --- polyunsaturated fatty acids (PUFAs) --- mutant strain --- Aurantiochytrium sp. --- transcriptome --- Xanthomonas campestris pv. campestris --- 6-pentyl-α-pyrone --- antibiosis --- Trichoderma --- secondary metabolites --- antibiofilm --- Gram-negative bacterium --- antibiotic resistance --- natural products --- angucycline --- aquayamycin --- glycosyltransferase --- Lake Baikal --- Streptomyces --- Talaromyces albobiverticillius 30548 --- submerged fermentation --- pigments --- biomass --- optimization --- Box–Behnken experimental design --- response surface modeling --- carnosic acid --- propolis --- antifungal action --- synergy --- Candida albicans --- biofilms --- sponges --- actinomycetes --- cryptic --- Micromonospora --- Nocardia --- Gordonia --- mycolic acid --- LC-HRESIMS --- N-functionalized amines --- N-methylanthranilate --- Corynebacterium glutamicum --- metabolic engineering --- sustainable production of quinoline precursors --- acridone --- quinazoline alkaloid drugs --- SARS-CoV-2 --- Covid-19 --- Mpro --- microbial natural products --- docking --- molecular dynamic simulation --- Serratiochelin A --- Serratiochelin C --- Serratia sp. --- siderophore --- iron --- anticancer --- microbial biotechnology --- degradation --- antibacterial --- S. aureus --- sparkling wine --- second fermentation --- fermentation by-products --- Saccharomyces cerevisiae flor yeast --- proteins --- Scopalina hapalia --- Actinomycetes --- Bacillus --- Fungi --- elastase inhibition --- tyrosinase inhibition --- CDK7 inhibition --- Fyn kinase inhibition --- catalase activation --- sirtuin 1 activation --- Curvularia papendorfii --- endophytic fungi --- human coronavirus HCoV 229E --- Staphylococcus sp. --- MRSA --- antiproliferative activity --- polyhydroxyacid --- kheiric acid --- insect --- mealworm --- gut bacteria --- OSMAC --- cyclic peptides --- biosynthetic pathway --- autophagy inducer --- fermentation --- Lactococcus lactis --- bacteriocin --- culture conditions --- medium compositions --- lactic acid fermentation --- Pediococcus acidilactici PA204 --- simultaneous saccharification and fermentation --- corn stover --- pyocyanin --- maize industry wastewater --- Pseudomonas aeruginosa NEJ01R --- redox metabolite --- response surface analysis --- bioproduction --- valorization --- electrochemical analysis --- sugarcane --- distillery waste water --- molasses spent wash --- vinasse --- fungi --- yeasts --- bioremediation --- COD --- discoloration --- antimicrobial --- antioxidant --- GNPS --- textiles --- cation-exchange resin --- adsorption --- removal --- ammonium --- cell viability --- mutant gdhA P. multocida B:2 --- cyanobacteria --- photosynthesis --- synthetic biology --- systems biology --- genome-scale model --- protoplast fusion --- novel compound discovery --- cell wall-deficiency --- heteroploidy --- Talaromyces --- azaphilone --- marine fungi --- N-threonyl-rubropunctamin --- PP-R --- greener extraction --- red pigments --- fungal pigments --- antinematode compound --- anthelminthic drugs --- marine epiphytic bacteria --- marine biofilm --- marine environment --- parasitic nematode --- Caenorhabditis elegans --- natural colors --- bio-pigments --- quorum sensing --- marine bacteria --- biosynthesis --- biological activities --- industrial applications --- therapeutic insights --- global pigment market --- terpenoids --- sesquiterpene production --- Rhodobacter capsulatus --- β-caryophyllene --- bioactivity --- phytopathogens --- plant pathogenic fungi --- plant growth-promoting bacteria --- microorganisms --- biotechnology --- screening --- production --- extraction --- bioactive properties --- perspectives