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The issue is dedicated to applications of Deep Brain Stimulation and, in this issue, we would like to highlight the new developments that are taking place in the field. These include the application of new technology to existing indications, as well as ‘new’ indications. We would also like to highlight the most recent clinical evidence from international multicentre trials. The issue will include articles relating to movement disorders, pain, psychiatric indications, as well as emerging indications that are not yet accompanied by clinical evidence. We look forward to your expert contribution to this exciting issue.

Autonomic dysfunction --- Novel Technology --- Pain --- Deep Brain Stimulation --- Movement Disorders

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Neuropathology --- Autonomic nervous system --- Autonomic dysfunction. --- Autonomic nervous system. --- Nervous system diseases. --- Internal medicine --- Diseases. --- Arterial hypertension --- Arterial hypertension.

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Disorders of the central and peripheral nerve systems have severe effects on gut function. Hence, people who have sustained spinal cord injury and multiple sclerosis, Parkinson’s disease, or spina bifida patients may suffer from severe bowel symptoms, including constipation, incontinence to stools, difficult bowel evacuation, or pain. For the present book, a number of international experts have described how disorders of the nerve system affect bowel function, how to assess and treat bowel symptoms, and how the bacterial composition of the bowel may be affected.

Medicine --- Neurology & clinical neurophysiology --- laxatives --- constipation --- adults --- prevalence --- utilisation --- gut microbiota --- spina bifida --- transanal irrigation --- urinary tract infection --- SCI --- MENTOR --- NBD --- fecal incontinence --- Parkinson’s disease --- autonomic --- gastrointestinal --- alpha-synuclein --- parasympathetic --- neurogenic bowel dysfunction --- low anterior resection syndrome --- faecal incontinence --- chronic constipation --- bowel dysfunction --- quality of life --- spinal cord injury --- multiple sclerosis --- pharmacological --- systematic review --- neurogenic bowel --- treatment assessment --- bowel function --- exoskeletal walking --- difficulty with evacuation --- neostigmine --- glycopyrrolate --- iontophoresis --- autonomic dysfunction --- motility --- investigations --- manometry --- breath test --- imaging --- diabetes mellitus --- postprandial hypotension --- food ingestion --- ambulatory blood pressure measurement --- cohort study --- pediatric --- children --- adolescent --- anorectal malformation --- cerebral palsy --- acute rehabilitation --- opioids --- SCI bowel management

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Autonomic Nervous System. --- Autonomic nervous system --- -Autonomic nervous system --- -Involuntary nervous system --- Nervous system, Autonomic --- Nervous system, Vegetative --- Systema nervosum autonomicum --- Vegetative nervous system --- Nervous system --- Vegetative Nervous System --- Visceral Nervous System --- Autonomic Nervous Systems --- Nervous System, Autonomic --- Nervous System, Vegetative --- Nervous System, Visceral --- Nervous Systems, Autonomic --- Nervous Systems, Vegetative --- Nervous Systems, Visceral --- System, Autonomic Nervous --- System, Vegetative Nervous --- System, Visceral Nervous --- Systems, Autonomic Nervous --- Systems, Vegetative Nervous --- Systems, Visceral Nervous --- Vegetative Nervous Systems --- Visceral Nervous Systems --- Pathophysiology --- Physiology --- Pathophysiology. --- Physiology. --- -Pathophysiology --- Autonomic Nervous System --- Involuntary nervous system --- Autonomic Nervous System Diseases --- ANS (Autonomic Nervous System) Diseases --- ANS Diseases --- Autonomic Central Nervous System Diseases --- Autonomic Diseases --- Autonomic Nervous System Disorders --- Autonomic Peripheral Nervous System Diseases --- Segmental Autonomic Dysfunction --- Central Autonomic Nervous System Diseases --- Disorders of the Autonomic Nervous System --- Nervous System Diseases, Autonomic --- Nervous System Diseases, Parasympathetic --- Nervous System Diseases, Sympathetic --- Parasympathetic Nervous System Diseases --- Peripheral Autonomic Nervous System Diseases --- Sympathetic Nervous System Diseases --- ANS Disease --- Autonomic Disease --- Autonomic Dysfunction, Segmental --- Autonomic Dysfunctions, Segmental --- Segmental Autonomic Dysfunctions