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techniques of individual submission --- enforced confession --- mental coercion --- witchcraft and torture --- menticide in Korea --- Pavlov --- the salivating dog --- the conditioning of man --- isolation and conditioning --- mass conditioning through speech --- political conditioning --- medication --- dependency on the drug provider --- ecstacy through drugs --- hypnotism and mental coercion --- therapy and coercion --- the psychodynamics of false confession --- blackmailing --- brainwashing --- the techniques of mass submission --- public-opinion engineering --- psychological warfare --- terror --- indoctrination --- totalitarianism --- black magic --- verbocracy --- semantic fog --- logocide --- labelomania --- demagogy --- interrogation --- detachment --- fear and terror --- unobtrusive coercion --- mental contagion --- self-betrayal --- loyalty --- nonconformity --- compulsion --- training against mental torture --- brainwashing and menticide --- education --- discipline and morale --- discipline and brainwashing --- group morale --- psychology --- automatization

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The principal aim of this book is to provide a wide range of information and a useful reference for researchers interested to investigate heavy mineral assemblages in different geological settings and for a variety of purposes. The methodological developments achieved in recent years for the identification of heavy minerals in a wide grain-size range are illustrated. All factors that affect heavy mineral concentration and relative proportions, including hydraulic sorting, mechanical abrasion, chemical weathering, and post-depositional dissolution, and all factors able to introduce analytical, environmental, or diagenetic bias are thoroughly addressed. A proper integration of multiple techniques including bulk sediment, multi-mineral, and single-mineral methods are discussed by renowned authors in their invited contributions.

heavy minerals --- correlation --- North Sea --- Jurassic --- Triassic --- Carboniferous --- Devonian --- relative and absolute abundances --- sampling strategy --- size-window for analysis --- heavy mineral point-counting --- provenance and plate-tectonic setting --- chemical weathering --- hydraulic sorting --- recycling --- diagenesis --- sediment --- provenance --- statistics --- zircon --- point counting --- petrography --- mineral grains composition --- surface textures --- sources --- WNW Portuguese Continental Margin --- Raman spectroscopy --- sedimentary provenance --- automatization --- heavy mineral --- Pliocene --- the Changjiang Delta --- amphibole --- surface texture --- garnet --- epidote --- pyroxene --- provenance tracers --- varietal studies --- mineral chemistry --- semi-automated Raman counting --- Ladakh-Kohistan arcs --- Himalaya --- Nanga Parbat --- Karakorum --- Indus river --- amphiboles --- tremolite --- actinolite --- provenance analysis --- tectonic versus climatic control --- early-middle Pleistocene transition --- Yellow River terraces --- Lanzhou (northern China) --- sieving of fine silt --- fallacy of laser granulometry --- benthic foraminifera --- Ganga–Brahmaputra river system --- Bay of Bengal --- Himalayan orogen --- bulk-sediment petrography --- bulk-sediment geochemistry --- selective entrainment --- suspension sorting --- chemical indices of weathering --- sediment budgets --- Brahmaputra River --- Ganga River --- handbook for laboratory procedures --- nontoxic heavy liquids --- wet sieving of silt --- zircon separation --- heavy-mineral mounts --- n/a --- Ganga-Brahmaputra river system

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This book serves to highlight the pharmacokinetics/drug–drug interactions and mechanistic understanding in relation to the drug-metabolizing enzymes and drug transporters.This book presents a series of drug metabolism and transport mechanisms that govern the pharmacokinetic features of therapeutic drugs as well as natural herbal medicines. It also covers the pharmacokinetic interactions caused by inhibiting or inducing the metabolic or transport activities under disease states or the coadministration of potential inhibitors. It also deals with microenvironmental pharmacokinetic profiles as well as population pharmacokinetics, which gives new insights regarding the pharmacokinetic features with regard to drug metabolism and transporters.

Medicine --- Pharmaceutical industries --- tofacitinib --- dose-dependent pharmacokinetics --- hepatic and intestinal first-pass effect --- rats --- catalposide --- in vitro human metabolism --- UDP-glucuronosyltransferase --- sulfotransferase --- carboxylesterase --- celecoxib --- drug–drug interaction --- fluorescence --- HPLC --- metabolism --- repaglinide --- HSG4112 --- anti-obesity agent --- stereoselectivity --- pharmacokinetics --- compound K --- protopanaxadiol (PPD) --- biliary excretion --- intestinal metabolism --- Carthamus tinctorius extract --- notoginseng total saponins --- comparative pharmacokinetic study --- large volume direct injection --- compatibility mechanism --- mertansine --- human hepatocytes --- cytochrome P450 --- UDP-glucuronosyltransferases --- sodium-glucose cotransporter 2 (SGLT2) inhibitors --- DWP16001 --- kidney distribution --- inhibition mode --- diabetes --- transporter-enzyme interplay --- influx transporter --- efflux transporter --- physiologically based pharmacokinetic model --- cytochrome P450 enzymes --- tiropramide --- healthy Korean subjects --- modeling --- population pharmacokinetic --- quercetin --- breast cancer resistance protein --- inhibitor --- prazosin --- sulfasalazine --- kinetic analysis --- food–drug interactions --- Caco-2 --- EpiIntestinal --- first-pass --- P-gp --- BCRP --- drug transporter --- CYP3A4 --- oral availability --- automatization --- drug absorption --- drug dosing --- head-and-neck cancer --- real-time measurements --- taxanes --- tissue engineering --- UHPLC-MS/MS --- metformin --- verapamil --- drug interaction --- organic cation transporter 2 --- renal excretion --- acute renal failure --- gentamicin --- cisplatin --- hepatic CYP3A1(23) --- creatinine clearance --- renal clearance --- nonrenal clearance