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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

epilepsy --- comorbidities --- experimental-animal models --- clinical epilepsy --- antiepileptics drugs

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Science: general issues --- Pharmacology --- epilepsy --- comorbidities --- experimental-animal models --- clinical epilepsy --- antiepileptics drugs

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Anticonvulsants. --- Carbamazepine. --- Dibenzazepinecarboxamide --- Amides --- Anticonvulsants --- Anti-epileptic drugs --- Anticonvulsant drugs --- Antiepileptic agents --- Antiepileptics --- Central nervous system depressants --- Muscle relaxants --- Convulsions --- Chemotherapy

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This thorough volume delves into antiepileptic drug discovery with a comprehensive collection of innovative approaches for the development of antiepileptic therapies, focusing on novel molecular targets for antiepileptic drugs, computer-aided approaches for the identification of new drug candidates, and therapeutic strategies to overcome refractory epilepsy. The last section illustrates the potential benefits that network pharmacology and rational drug repurposing could bring to the antiepileptic drug discovery community. Written for the Methods in Pharmacology and Toxicology series, chapters include the kind of detailed description and implementation advice to ensure results in the laboratory. Authoritative and practical, Antiepileptic Drug Discovery: Novel Approaches aims to provide medicinal chemists, pharmacologists, and other researchers with the tools need to further explore the study of pharmacoresistant epilepsy and the discovery of new antiepileptic drugs.

Toxicology. --- Pharmacology/Toxicology. --- Chemicals --- Medicine --- Pharmacology --- Poisoning --- Poisons --- Toxicology --- Anticonvulsius --- Biologia molecular --- Biofísica molecular --- Bioquímica molecular --- Biofísica --- Bioquímica --- Histoquímica --- Biologia molecular vegetal --- Codi genètic --- Diagnòstic molecular --- Endocrinologia molecular --- Evolució molecular --- Farmacologia molecular --- Genètica molecular --- Glicòmica --- Metabolòmica --- Microbiologia molecular --- Neurobiologia molecular --- Patologia molecular --- Proteòmica --- Reconeixement molecular --- Biomolècules --- Antiepilèptics --- Agents antiepilèptics --- Medicaments anticonvulsius --- Relaxants musculars

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Anticonvulsants --- Epilepsy --- Chemotherapy --- Drug therapy --- -Chemotherapy --- -Brain --- Developmental disabilities --- Convulsions --- Spasms --- Anti-epileptic drugs --- Anticonvulsant drugs --- Antiepileptic agents --- Antiepileptics --- Central nervous system depressants --- Muscle relaxants --- Diseases --- Anticonvulsants. --- -Chemotherapy. --- -Anti-epileptic drugs --- drug therapy.