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Anemia --- Anémie --- Periodicals --- Périodiques --- Anemia. --- haematology --- anaemia --- Anaemia --- Blood --- Anemias --- Hepcidins --- Diseases --- Pathological haematology --- Hematologic Diseases

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Reticulocytes --- Erythrocytes --- Erythropoiesis --- senescence --- Clearance --- Anaemia --- Membrane Physiology --- Rheology --- Microfluidics

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This book deals with a very common condition, anemia, which might interest not only the physicians but also other healthcare professionals and researchers dealing with anemic patients. The objective of this book was to collect and compile up-to-date information from reputable researchers of different countries of the world to disseminate the latest information about the common types of anemia in some specific physiological and pathological conditions including pathophysiology and the use of algorithms as a tool to minimize the laboratory tests and accurate diagnosis of the underlying cause. In total, there are 13 chapters in this book where the authors shared their research findings and real-life experiences in managing their patients with anemia.

Anemia. --- Anaemia --- Blood --- Diseases --- Medicine --- Internal Medicine --- Infectious Diseases --- Health Sciences

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This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact

Science: general issues --- Physiology --- Reticulocytes --- Erythrocytes --- Erythropoiesis --- senescence --- Clearance --- Anaemia --- Membrane Physiology --- Rheology --- Microfluidics

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L’anémie hémolytique à médiation immune fait partie des manifestations les plus fréquentes de trouble auto-immun et hématologique chez nos animaux de compagnie. Elle se caractérise par une lyse excessive des érythrocytes de l’hôte par son propre système immunitaire. Bien que le mécanisme et la gestion thérapeutique de cette pathologie soient actuellement bien connus, le taux de mortalité reste élevé. Un bilan d’extension thoracique et abdominal est actuellement recommandé afin de trouver la cause de l’hémolyse. Il existe cependant, un manque de données standardisées concernant les résultats échographiques chez les animaux de compagnie atteints d'anémie hémolytique à médiation immune (IMHA). Le but de cette étude est d’identifier les anomalies abdominales visibles à l’échographie, chez des patients atteints d’IMHA. Les résultats échographiques de 69 patients (61 chiens et 8 chats) pris en charge à l'Hôpital Vétérinaire de Liège entre 2013 et 2018 ont été examinés et détaillés en fonction de la cause de l’IMHA. Les résultats échographiques étaient compatibles avec une hématopoïèse extra-médullaire ainsi que des modifications hypoxiques et réactionnelles. Une augmentation modérée à sévère de la taille (63,8% ; 44/69) et de l'échogénicité hépatique (52,2% ; 36/69) a été fréquemment observée. Sur la plupart de nos patients (20,3% ; 14/69), le parenchyme présentait un aspect nodulaire et hétérogène. Une splénomégalie et un parenchyme splénique hétérogène ont été rapportés chez 40 (58% ; 40/69) et 31 patients (45% ; 31/69), respectivement. Un épanchement abdominal léger à modéré a été observé chez 32 patients (46,4% ; 32/69), particulièrement en partie crâniale (27,5% ; 19/69). Les spots hyperéchogènes libres dans la vessie étaient fréquents (50,7% ; 35/69). Enfin, un tiers (33,3% ; 23/69) ont présenté un élargissement des ganglions lymphatiques abdominaux. Immune-mediated haemolytic anaemia is one of the most common manifestations of autoimmune and haematological disorders in companion animals. It is characterized by an excessive lysis of the erythrocytes of the host by its own immune system. Although the mechanism and therapeutic management of this pathology are currently well known, the mortality rate remains high. An assessment of thoracic and abdominal extension is currently recommended to find the cause of haemolysis. However, there is a lack of standardized data regarding ultrasonographic findings in companion animals affected by immune-mediated haemolytic anaemia (IMHA). The aim of this study is to identify the anomalies on abdominal ultrasound scans in patients suffering from IMHA. The ultrasonographic findings from 69 patients (61 dogs and 8 cats) seen at the Veterinary Hospital of Liège University between the year 2013 and 2018 were screened and itemized according to the cause of the IMHA. The ultrasonographic findings were consistent with extramedullary haematopoiesis as well as hypoxic and reactive changes. A moderate to severe increase in hepatic size (63,8%; 44/69) and echogenicity (52,2%; 36/69) was frequently seen, along with nodular and heterogeneous hepatic parenchyma (20,3%; 14/69). Splenomegaly and heterogeneous splenic parenchyma were reported in 40 (58%; 40/69) and 31 patients (45%; 31/69) respectively. Mild to moderate abdominal effusion was found in 32 patients (46,4%; 32/69). Floating hyperechoic spots in the urinary bladder were frequent (50,7%; 35/69). Finally, a third (33,3%; 23/69) presented enlargement of abdominal lymph nodes.

Echographie --- Anémie hémolytique à médiation immune --- Ultrasonography --- Immune-mediated haemolytic anaemia --- Sciences du vivant > Médecine vétérinaire & santé animale