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Book
Evidence-based Advance and Management of Adverse Events of Immunotherapy for Cancer
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Year: 2020 Publisher: Frontiers Media SA

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Abstract

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact


Book
Evidence-based Advance and Management of Adverse Events of Immunotherapy for Cancer
Authors: --- ---
Year: 2020 Publisher: Frontiers Media SA

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Abstract

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact


Book
Evidence-based Advance and Management of Adverse Events of Immunotherapy for Cancer
Authors: --- ---
Year: 2020 Publisher: Frontiers Media SA

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Abstract

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact


Book
Human African Trypanosomiasis (Sleeping Sickness) : The Road to Elimination Revisited-Achievements and Remaining Challenges
Author:
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

As it is a goal to eliminate human African trypanosomiasis (HAT; sleeping sickness) as a public health problem by 2020 and interrupt transmission by 2030, this is a good moment to reflect on what we have achieved, what we want to achieve, and what could get in our way. HAT has a reputation for spectacular reappearances, and the latest peak of 40,000 reported and over 300,000 estimated cases only dates back to 1998. Efforts of the WHO and partners as well as the development of simpler and much better-tolerated treatments, improved diagnostics, and vector control tools made it possible to reduce this number by 95%. Case identification and confirmation remain complex and require specific skills, treatment remains error-prone and reports on long-term survivors have emerged, and the relevance of the animal reservoir for T. b. gambiense HAT needs clarification. In addition, to win the “end game” against this massively stigmatized disease, the human factor will play a key role. This Special Issue addresses many of the burning topics about disease elimination in its 12 research and 7 review articles and one case study. The papers critically reflect the approaches used, investigate the mentioned challenges, and propose novel approaches and interventions from various points of view.

Keywords

Medicine --- Epidemiology & medical statistics --- (+)-spectaline --- iso-6-spectaline --- Trypanosoma brucei rhodesiense --- autophagy --- apoptosis --- cross-talk --- trypanosomosis --- iron --- transferrin --- transferrin receptor --- nutritional immunity --- flagellar pocket --- Human African Trypanosomiasis (HAT) --- mydriasis --- neurological signs --- eradication --- re-emergence --- human African trypanosomiasis --- treatment --- melarsoprol --- adverse event --- encephalopathy --- human leukocyte antigen --- association study --- disease elimination --- disease eradication --- frontline workers --- DR Congo --- mobile screening --- qualitative methods --- sequelae --- serology --- oligosymptomatic HAT --- product development partnerships --- research and development --- medical innovation --- donor policy --- African trypanosomiasis --- sleeping sickness --- trypanosoma brucei --- drugs --- drug resistance --- history --- human Africa trypanosomiasis --- fexinidazole --- home-based treatment --- patient-centred care --- Uganda --- elimination --- T. b. gambiense --- g-HAT --- T. b. rhodesiense --- r-HAT --- neglected tropical diseases --- Trypanosoma brucei --- drug discovery --- high-throughput screening --- blood-brain barrier --- brain permeability --- pharmacology --- phenotypic drug screening --- Haemoparasites --- animal reservoirs --- Trypanosoma growth inhibitors --- chemotherapy --- pafuramidine --- acoziborole --- African sleeping sickness --- development of treatment --- suramin --- medical history --- political history --- clinical research --- health system strengthening --- South Sudan --- diagnosis --- symptoms --- treatment-seeking --- case detection --- embodiment --- expertise --- serendipity --- CATT positive serological suspects --- active follow-up strategy --- (+)-spectaline --- iso-6-spectaline --- Trypanosoma brucei rhodesiense --- autophagy --- apoptosis --- cross-talk --- trypanosomosis --- iron --- transferrin --- transferrin receptor --- nutritional immunity --- flagellar pocket --- Human African Trypanosomiasis (HAT) --- mydriasis --- neurological signs --- eradication --- re-emergence --- human African trypanosomiasis --- treatment --- melarsoprol --- adverse event --- encephalopathy --- human leukocyte antigen --- association study --- disease elimination --- disease eradication --- frontline workers --- DR Congo --- mobile screening --- qualitative methods --- sequelae --- serology --- oligosymptomatic HAT --- product development partnerships --- research and development --- medical innovation --- donor policy --- African trypanosomiasis --- sleeping sickness --- trypanosoma brucei --- drugs --- drug resistance --- history --- human Africa trypanosomiasis --- fexinidazole --- home-based treatment --- patient-centred care --- Uganda --- elimination --- T. b. gambiense --- g-HAT --- T. b. rhodesiense --- r-HAT --- neglected tropical diseases --- Trypanosoma brucei --- drug discovery --- high-throughput screening --- blood-brain barrier --- brain permeability --- pharmacology --- phenotypic drug screening --- Haemoparasites --- animal reservoirs --- Trypanosoma growth inhibitors --- chemotherapy --- pafuramidine --- acoziborole --- African sleeping sickness --- development of treatment --- suramin --- medical history --- political history --- clinical research --- health system strengthening --- South Sudan --- diagnosis --- symptoms --- treatment-seeking --- case detection --- embodiment --- expertise --- serendipity --- CATT positive serological suspects --- active follow-up strategy


Book
Pharmacy Practice and Administration
Author:
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

The scope of the Special Issue is research and reviews on evaluations of current practice, innovations in medication management, developments in therapeutics, and pharmaceutical science research that informs and improves practice and administration, as well as the social and administrative pharmacy. We will mainly feature original research, reviews, short reports, and clinical studies, but also case reports, descriptive/how-to, and commentary submissions for consideration.

Keywords

Medicine --- Pharmaceutical industries --- older adults --- polypharmacy --- internal medicine ward --- community pharmacy --- drug disposal --- unused medication --- environment --- awareness --- practice --- ambulatory care facilities --- health workforce --- pharmacists --- Taiwan --- Commonwealth Partnerships for Antimicrobial Stewardship (CwPAMS) --- National Health Service (NHS) --- Chief Pharmaceutical Officer’s Global Health Fellowship --- CPhOGH Fellows --- CwPAMS --- pharmacy --- fellowship --- health partnerships --- antimicrobial resistance (AMR) --- global health --- leadership --- non-prescription medicines --- emergency contraception --- community pharmacies --- information gathering --- availability --- pricing --- mystery calls --- ulipristal acetate --- levonorgestrel --- Germany --- e-prescription --- prescription writing --- Jazan --- Saudi Arabia --- prescription errors --- medicine consumption --- defined daily dose --- adolescents and young adults --- cancer patients --- fragility --- pain --- MUR --- medication review --- barriers --- pharmacist --- pregabalin --- abuse --- community pharmacists --- reproductive health --- contraception --- emergency contraceptives --- patient education --- biosensing technology --- digital medicine system --- medication adherence --- medication event monitoring system --- nonadherence --- prescription opioids --- mortality --- standardized mortality ratio --- underlying cause of death --- prescriptions --- community pharmacy services --- emergency prescribing --- pharmacy practice --- pharmacy law and regulation --- COVID-19 --- additional monitoring --- black triangle --- adverse event reporting --- pharmacovigilance --- intervention --- outcomes --- systematic review --- pharmacy education --- decision to study in pharmacy --- selecting pharmacy as a first choice --- pharmacogenomics --- learning activity --- asynchronous learning --- virtual learning --- student survey --- Program of All-Inclusive Care for the Elderly --- adverse drug events --- medication-related problems --- drug-related problems --- medication safety --- Medicare --- Medicaid --- financial management --- pharmacy management --- business --- entrepreneurship --- pharmacy students --- perception --- attitudes --- ability --- interprofessional --- simulation --- acute care --- nursing --- students --- standardized patients --- high fidelity --- SPICE-R2 --- older adults --- polypharmacy --- internal medicine ward --- community pharmacy --- drug disposal --- unused medication --- environment --- awareness --- practice --- ambulatory care facilities --- health workforce --- pharmacists --- Taiwan --- Commonwealth Partnerships for Antimicrobial Stewardship (CwPAMS) --- National Health Service (NHS) --- Chief Pharmaceutical Officer’s Global Health Fellowship --- CPhOGH Fellows --- CwPAMS --- pharmacy --- fellowship --- health partnerships --- antimicrobial resistance (AMR) --- global health --- leadership --- non-prescription medicines --- emergency contraception --- community pharmacies --- information gathering --- availability --- pricing --- mystery calls --- ulipristal acetate --- levonorgestrel --- Germany --- e-prescription --- prescription writing --- Jazan --- Saudi Arabia --- prescription errors --- medicine consumption --- defined daily dose --- adolescents and young adults --- cancer patients --- fragility --- pain --- MUR --- medication review --- barriers --- pharmacist --- pregabalin --- abuse --- community pharmacists --- reproductive health --- contraception --- emergency contraceptives --- patient education --- biosensing technology --- digital medicine system --- medication adherence --- medication event monitoring system --- nonadherence --- prescription opioids --- mortality --- standardized mortality ratio --- underlying cause of death --- prescriptions --- community pharmacy services --- emergency prescribing --- pharmacy practice --- pharmacy law and regulation --- COVID-19 --- additional monitoring --- black triangle --- adverse event reporting --- pharmacovigilance --- intervention --- outcomes --- systematic review --- pharmacy education --- decision to study in pharmacy --- selecting pharmacy as a first choice --- pharmacogenomics --- learning activity --- asynchronous learning --- virtual learning --- student survey --- Program of All-Inclusive Care for the Elderly --- adverse drug events --- medication-related problems --- drug-related problems --- medication safety --- Medicare --- Medicaid --- financial management --- pharmacy management --- business --- entrepreneurship --- pharmacy students --- perception --- attitudes --- ability --- interprofessional --- simulation --- acute care --- nursing --- students --- standardized patients --- high fidelity --- SPICE-R2


Book
Pharmacy Practice and Administration
Author:
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

The scope of the Special Issue is research and reviews on evaluations of current practice, innovations in medication management, developments in therapeutics, and pharmaceutical science research that informs and improves practice and administration, as well as the social and administrative pharmacy. We will mainly feature original research, reviews, short reports, and clinical studies, but also case reports, descriptive/how-to, and commentary submissions for consideration.

Keywords

Medicine --- Pharmaceutical industries --- older adults --- polypharmacy --- internal medicine ward --- community pharmacy --- drug disposal --- unused medication --- environment --- awareness --- practice --- ambulatory care facilities --- health workforce --- pharmacists --- Taiwan --- Commonwealth Partnerships for Antimicrobial Stewardship (CwPAMS) --- National Health Service (NHS) --- Chief Pharmaceutical Officer’s Global Health Fellowship --- CPhOGH Fellows --- CwPAMS --- pharmacy --- fellowship --- health partnerships --- antimicrobial resistance (AMR) --- global health --- leadership --- non-prescription medicines --- emergency contraception --- community pharmacies --- information gathering --- availability --- pricing --- mystery calls --- ulipristal acetate --- levonorgestrel --- Germany --- e-prescription --- prescription writing --- Jazan --- Saudi Arabia --- prescription errors --- medicine consumption --- defined daily dose --- adolescents and young adults --- cancer patients --- fragility --- pain --- MUR --- medication review --- barriers --- pharmacist --- pregabalin --- abuse --- community pharmacists --- reproductive health --- contraception --- emergency contraceptives --- patient education --- biosensing technology --- digital medicine system --- medication adherence --- medication event monitoring system --- nonadherence --- prescription opioids --- mortality --- standardized mortality ratio --- underlying cause of death --- prescriptions --- community pharmacy services --- emergency prescribing --- pharmacy practice --- pharmacy law and regulation --- COVID-19 --- additional monitoring --- black triangle --- adverse event reporting --- pharmacovigilance --- intervention --- outcomes --- systematic review --- pharmacy education --- decision to study in pharmacy --- selecting pharmacy as a first choice --- pharmacogenomics --- learning activity --- asynchronous learning --- virtual learning --- student survey --- Program of All-Inclusive Care for the Elderly --- adverse drug events --- medication-related problems --- drug-related problems --- medication safety --- Medicare --- Medicaid --- financial management --- pharmacy management --- business --- entrepreneurship --- pharmacy students --- perception --- attitudes --- ability --- interprofessional --- simulation --- acute care --- nursing --- students --- standardized patients --- high fidelity --- SPICE-R2


Book
Pharmacy Practice and Administration
Author:
Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

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Bookmark

Abstract

The scope of the Special Issue is research and reviews on evaluations of current practice, innovations in medication management, developments in therapeutics, and pharmaceutical science research that informs and improves practice and administration, as well as the social and administrative pharmacy. We will mainly feature original research, reviews, short reports, and clinical studies, but also case reports, descriptive/how-to, and commentary submissions for consideration.

Keywords

older adults --- polypharmacy --- internal medicine ward --- community pharmacy --- drug disposal --- unused medication --- environment --- awareness --- practice --- ambulatory care facilities --- health workforce --- pharmacists --- Taiwan --- Commonwealth Partnerships for Antimicrobial Stewardship (CwPAMS) --- National Health Service (NHS) --- Chief Pharmaceutical Officer’s Global Health Fellowship --- CPhOGH Fellows --- CwPAMS --- pharmacy --- fellowship --- health partnerships --- antimicrobial resistance (AMR) --- global health --- leadership --- non-prescription medicines --- emergency contraception --- community pharmacies --- information gathering --- availability --- pricing --- mystery calls --- ulipristal acetate --- levonorgestrel --- Germany --- e-prescription --- prescription writing --- Jazan --- Saudi Arabia --- prescription errors --- medicine consumption --- defined daily dose --- adolescents and young adults --- cancer patients --- fragility --- pain --- MUR --- medication review --- barriers --- pharmacist --- pregabalin --- abuse --- community pharmacists --- reproductive health --- contraception --- emergency contraceptives --- patient education --- biosensing technology --- digital medicine system --- medication adherence --- medication event monitoring system --- nonadherence --- prescription opioids --- mortality --- standardized mortality ratio --- underlying cause of death --- prescriptions --- community pharmacy services --- emergency prescribing --- pharmacy practice --- pharmacy law and regulation --- COVID-19 --- additional monitoring --- black triangle --- adverse event reporting --- pharmacovigilance --- intervention --- outcomes --- systematic review --- pharmacy education --- decision to study in pharmacy --- selecting pharmacy as a first choice --- pharmacogenomics --- learning activity --- asynchronous learning --- virtual learning --- student survey --- Program of All-Inclusive Care for the Elderly --- adverse drug events --- medication-related problems --- drug-related problems --- medication safety --- Medicare --- Medicaid --- financial management --- pharmacy management --- business --- entrepreneurship --- pharmacy students --- perception --- attitudes --- ability --- interprofessional --- simulation --- acute care --- nursing --- students --- standardized patients --- high fidelity --- SPICE-R2


Book
Human African Trypanosomiasis (Sleeping Sickness) : The Road to Elimination Revisited-Achievements and Remaining Challenges
Author:
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

Loading...
Export citation

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Bookmark

Abstract

As it is a goal to eliminate human African trypanosomiasis (HAT; sleeping sickness) as a public health problem by 2020 and interrupt transmission by 2030, this is a good moment to reflect on what we have achieved, what we want to achieve, and what could get in our way. HAT has a reputation for spectacular reappearances, and the latest peak of 40,000 reported and over 300,000 estimated cases only dates back to 1998. Efforts of the WHO and partners as well as the development of simpler and much better-tolerated treatments, improved diagnostics, and vector control tools made it possible to reduce this number by 95%. Case identification and confirmation remain complex and require specific skills, treatment remains error-prone and reports on long-term survivors have emerged, and the relevance of the animal reservoir for T. b. gambiense HAT needs clarification. In addition, to win the “end game” against this massively stigmatized disease, the human factor will play a key role. This Special Issue addresses many of the burning topics about disease elimination in its 12 research and 7 review articles and one case study. The papers critically reflect the approaches used, investigate the mentioned challenges, and propose novel approaches and interventions from various points of view.

Keywords

(+)-spectaline --- iso-6-spectaline --- Trypanosoma brucei rhodesiense --- autophagy --- apoptosis --- cross-talk --- trypanosomosis --- iron --- transferrin --- transferrin receptor --- nutritional immunity --- flagellar pocket --- Human African Trypanosomiasis (HAT) --- mydriasis --- neurological signs --- eradication --- re-emergence --- human African trypanosomiasis --- treatment --- melarsoprol --- adverse event --- encephalopathy --- human leukocyte antigen --- association study --- disease elimination --- disease eradication --- frontline workers --- DR Congo --- mobile screening --- qualitative methods --- sequelae --- serology --- oligosymptomatic HAT --- product development partnerships --- research and development --- medical innovation --- donor policy --- African trypanosomiasis --- sleeping sickness --- trypanosoma brucei --- drugs --- drug resistance --- history --- human Africa trypanosomiasis --- fexinidazole --- home-based treatment --- patient-centred care --- Uganda --- elimination --- T. b. gambiense --- g-HAT --- T. b. rhodesiense --- r-HAT --- neglected tropical diseases --- Trypanosoma brucei --- drug discovery --- high-throughput screening --- blood–brain barrier --- brain permeability --- pharmacology --- phenotypic drug screening --- Haemoparasites --- animal reservoirs --- Trypanosoma growth inhibitors --- chemotherapy --- pafuramidine --- acoziborole --- African sleeping sickness --- development of treatment --- suramin --- medical history --- political history --- clinical research --- health system strengthening --- South Sudan --- diagnosis --- symptoms --- treatment-seeking --- case detection --- embodiment --- expertise --- serendipity --- CATT positive serological suspects --- active follow-up strategy --- n/a --- blood-brain barrier


Book
A Meeting of Minds: In Recognition of the Contributions of Randall J. Cohrs
Authors: --- ---
ISBN: 303655260X 3036552596 Year: 2022 Publisher: MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

A Special Issue in memory of Randall J. Cohrs, Ph.D. Topics include original research reports on a variety of viruses as well as reviews and commentaries on Randy’s contributions to many investigations.

Keywords

Research & information: general --- Biology, life sciences --- varicella-zoster virus --- Oka strain --- human herpesvirus 6 --- human herpesvirus 7 --- corticosteroids --- serious adverse event --- herpes zoster --- IL-6 --- IL-10 --- innate immunity --- VLT --- VLT-ORF63 --- CRISPR/Cas9 --- BAC mutagenesis --- flavivirus --- SARS-CoV-2 --- pandemic preparedness --- host–virus interactions --- prion --- vaccines --- interferon lambda --- virus --- herpes simplex virus type 1 --- herpes simplex virus type 2 --- neonatal herpesvirus infection --- HSV UL6 --- herpesvirus encephalitis --- herpesvirus hepatitis --- acyclovir --- HerpeSelect test --- viral sequencing --- HELLP syndrome --- lipids --- dengue virus --- acyl-CoA --- acyl-CoA thioesterase --- fatty acids --- membranes --- rheostat --- fatty acyl-CoA --- Marek’s disease virus --- live-cell genome visualization --- lytic replication --- T cells --- latency --- genome integration --- TetO/TetR system --- varicella zoster virus --- reactivation --- genome cleavage --- AAV --- antiviral therapies --- HSV-1 --- cornea --- trigeminal ganglia --- interferon-γ --- interferon stimulatory genes --- TRIM21 --- HSV --- EBV --- KSHV --- MHV68 --- PIC --- transcription --- productive elongation --- mRNA --- rRNA --- tRNA --- herpes --- viral reactivation --- spaceflight --- dermatitis --- stress --- immune depression --- antiviral drugs --- bacterial artificial chromosome --- luciferase --- bioluminescence imaging --- skin organ culture --- humanized mice --- β-Coronavirus --- mouse hepatitis virus-A59/MHV-A59 --- mouse hepatitis virus-2/MHV2 spike protein --- fusion peptide/FP --- cell-to-cell fusion (fusogenicity) --- neuropathogenesis --- hepatitis --- demyelination --- structural rigidity --- simian varicella virus --- herpesvirus --- varicella --- VZV --- neuro-attenuated --- ORF7 --- vaccine --- n/a --- antiviral --- COVID-19 --- drug discovery --- coronavirus --- spike protein --- Mpro --- RdRp --- PLpro --- skin --- epidermis --- keratinocytes --- epidermal differentiation --- cutaneous blistering lesions --- keratins --- autophagy --- immunity --- human neuron culture --- non-coding RNA --- CD8 T cell --- T-cell epitope --- NK cell --- KIR3DL1 --- HLA-B*57:01 --- herpes simplex virus --- zoster --- skin pathogenesis --- HSV-2 --- neurons --- cell culture --- varicella-zoster --- gene expression --- ganglion --- autopsy --- saliva --- salivary VZV DNA --- dengue viruses --- Aedes aegypti --- adaptive mutation --- host-virus interactions --- Marek's disease virus

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