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Galectins are a family of soluble beta-galactoside-binding proteins with diverse glycan-dependent and glycan-independent functions outside and inside the cell. There are sixteen recognized mammalian galectin genes, and their expression profiles are very different between cell types, tissues, and species. This Special Issue covers recent progress in the field of the cell biology of galectins, relevant concepts of galectin regulatory mechanisms, and biomedical aspects of these unique multifunctional proteins.

Research & information: general --- Biology, life sciences --- galectin-7 --- p53 --- MMP-9 --- cancer --- gain-of-function --- vasculature --- gene expression --- tube formation --- sprouting --- VEGF --- integrins --- galectin --- extracellular matrix --- microenvironment --- Yersinia enterocolitica --- YopP --- Galectin-1 --- nitric oxide --- macrophages --- epithelial tissues --- apoptosis --- targeting --- inhibitors --- β-hairpin --- β-sandwich --- blood group B --- lectin --- sugar code --- LGALS16 --- placenta --- brain tissues --- cell differentiation --- transcription factor --- miRNA --- galectin-3 --- cardiac fibrosis --- heart failure --- atrial fibrillation --- chronic inflammation --- MMPs --- microRNAs --- lncRNAs --- pectin --- structure and function --- bioactive polysaccharides --- galectin-3 inhibition --- galacto-oligosaccharides --- galectins --- intestinal epithelial cells --- β-3′galactosyllactose --- immunomodulation --- mucosal immunity --- O-GlcNAc --- unconventional secretion --- extraembryonic endoderm --- n/a --- β-3'galactosyllactose

Choose an application

• Reference Manager
• EndNote
• RefWorks (Direct export to RefWorks)

Galectins are a family of soluble beta-galactoside-binding proteins with diverse glycan-dependent and glycan-independent functions outside and inside the cell. There are sixteen recognized mammalian galectin genes, and their expression profiles are very different between cell types, tissues, and species. This Special Issue covers recent progress in the field of the cell biology of galectins, relevant concepts of galectin regulatory mechanisms, and biomedical aspects of these unique multifunctional proteins.

Research & information: general --- Biology, life sciences --- galectin-7 --- p53 --- MMP-9 --- cancer --- gain-of-function --- vasculature --- gene expression --- tube formation --- sprouting --- VEGF --- integrins --- galectin --- extracellular matrix --- microenvironment --- Yersinia enterocolitica --- YopP --- Galectin-1 --- nitric oxide --- macrophages --- epithelial tissues --- apoptosis --- targeting --- inhibitors --- β-hairpin --- β-sandwich --- blood group B --- lectin --- sugar code --- LGALS16 --- placenta --- brain tissues --- cell differentiation --- transcription factor --- miRNA --- galectin-3 --- cardiac fibrosis --- heart failure --- atrial fibrillation --- chronic inflammation --- MMPs --- microRNAs --- lncRNAs --- pectin --- structure and function --- bioactive polysaccharides --- galectin-3 inhibition --- galacto-oligosaccharides --- galectins --- intestinal epithelial cells --- β-3'galactosyllactose --- immunomodulation --- mucosal immunity --- O-GlcNAc --- unconventional secretion --- extraembryonic endoderm