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Focuses on the synergism played by crystallography and drug discovery. This work comprises papers presented at the 40th Erice Course held from 28 May to 8 June 2008.

Biomolecules -- Congresses. --- Bioterrorism -- Prevention -- Congresses. --- Crystallography -- Congresses. --- Drug development -- Congresses. --- Macromolecules -- Structure -- Congresses. --- Medicine, Preventive -- Congresses. --- Proteins -- Biotechnology -- Congresses. --- X-ray crystallography -- Congresses. --- Macromolecules --- Proteins --- X-ray crystallography --- Drug development --- Drug Design --- Crystallography --- Macromolecular Substances --- Chemistry, Physical --- Drug Discovery --- Amino Acids, Peptides, and Proteins --- Chemicals and Drugs --- Chemistry Techniques, Analytical --- Investigative Techniques --- Chemistry, Pharmaceutical --- Chemistry --- Natural Science Disciplines --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Pharmacology --- Disciplines and Occupations --- Biological Science Disciplines --- Materials Science --- Organic Chemistry --- Chemical & Materials Engineering --- Engineering & Applied Sciences --- Physical Sciences & Mathematics --- Structure --- Biotechnology --- Development of drugs --- Drugs --- New drug development --- Development --- Physics. --- Computer simulation. --- Proteins. --- Bioinformatics. --- Crystallography. --- Protein-Ligand Interactions. --- Simulation and Modeling. --- Protein Structure. --- Leptology --- Physical sciences --- Mineralogy --- Bio-informatics --- Biological informatics --- Biology --- Information science --- Computational biology --- Systems biology --- Proteids --- Biomolecules --- Polypeptides --- Proteomics --- Computer modeling --- Computer models --- Modeling, Computer --- Models, Computer --- Simulation, Computer --- Electromechanical analogies --- Mathematical models --- Simulation methods --- Model-integrated computing --- Natural philosophy --- Philosophy, Natural --- Dynamics --- Data processing --- Pharmacy --- Molecules --- Supramolecular chemistry --- RNA-ligand interactions. --- Biochemistry. --- Crystallography and Scattering Methods. --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Medical sciences --- Composition --- Proteins .