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Innovations in antiviral development and the detection of virus infection : proceedings of the Eastern Pennsylvania Branch of the American Society for microbiology symposium on ... , November 15-16, 1990, Philadelphia
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ISBN: 0306442094 1461365333 1461534623 Year: 1992 Volume: vol 312 Publisher: New York London Plenum Press


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Diagnostic séro-immunologique des viroses humaines et animales
Authors: --- ---
ISBN: 2224000944 9782224000943 Year: 1974 Publisher: Paris: Maloine,

Essentials of diagnostic virology
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ISBN: 0443076324 9780443076329 Year: 2000 Publisher: New York: Churchill Livingstone,


Book
Therapy of Viral Infections
Authors: ---
ISBN: 9783662467596 3662467585 9783662467589 3662467593 Year: 2015 Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : Imprint: Springer,

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Abstract

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.


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Culture negative orthopedic biofilm infections
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ISSN: 18639607 ISBN: 3642295533 3642446833 3642295541 1283944855 Year: 2012 Publisher: Heidelberg [Germany] ; New York : Springer,

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Abstract

During the recent transition between acute diseases caused by swarms of single planktonic bacteria, and chronic infections caused by bacteria growing in slime-enclosed biofilms, a general clinical consensus has emerged that pathologies with bacterial etiologies are frequently culture negative. Because biofilm infections now affect 17 million Americans per year (killing approximately 450,000), the suggestion that these common and lethal infections regularly go unnoticed by the only FDA-approved method for their detection and characterization is a matter of urgent concern. Biologically, we would expect that planktonic bacterial cells would colonize any new surface, including the surface of an agar plate, while the specialized sessile cells of a biofilm community would have no such proclivity. In the study of biofilm diseases ranging from otitis media to prostatitis, it was found that direct microscopy and DNA- and RNA-based molecular methods regularly document the presence of living bacteria in tissues and samples that are culture negative. The editors selected orthopedic biofilm infections as the subject of this book because these infections occur against a background of microbiological sterility in which modern molecular methods would be expected to find bacterial DNA, RNA-based microscopic methods would be expected to locate bacterial cells, and cultures would be negative. Moreover, in Orthopedics we find an already biofilm-adapted surgical group in which current strategies are based on the meticulous removal of compromised tissues, antibiotic options as based on high biofilm-killing local doses, and there are practical bedside strategies for dealing with biofilm infections. So here is where the new paradigm of biofilm infection meets the equally new paradigm of the culture negativity of biofilms, and this volume presents a conceptual synthesis that may soon combine the most effective molecular methods for the detection and identification of bacteria with a surgical discipline that is ready to help patients. .


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Leeuwenhoek's Legatees and Beijerinck's Beneficiaries : A History of Medical Virology in The Netherlands
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ISBN: 9463720111 9048544068 9789463720113 Year: 2020 Publisher: Amsterdam Amsterdam University Press

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Abstract

This book offers a tour of the history of medical virology in the Netherlands from the nineteenth century to the new millennium. Beginning with the discovery of the first virus by Martinus Beijerinck in 1898, the authors investigate the reception and redefinition of his concept in medical circles and its implications for medical practice, particularly in the diagnosis and prevention of viral infections. The relatively slow progress of these areas in the first half of the twentieth century and their explosive growth in the wake of molecular techniques are examined. The surveillance and control of virus diseases in the field of public health is treated in depth, as are tumour virus research and the important Dutch contributions to technical developments instrumental in advancing virology worldwide. Particular attention is paid to oft forgotten virus research in the former Dutch colonies in the East and West Indies and Africa.

Keywords

Modern history to 20th century: c 1700 to c 1900 --- History of medicine --- Medical microbiology & virology --- Medical virology --- History --- Beijerinck, M. W. --- Medical microbiology --- Virology --- Virus diseases --- Virology-history, History-nineteenth century, History-twentieth century, Virology-methods, Virus diseases- diagnosis, Virus diseases-history. --- 1800-2099 --- Netherlands. --- Austrian Netherlands --- Aynacha Jach'a Markanaka --- Batavia --- Belanda --- Beulanda --- Çheer Injil --- Çheer y Vagheragh --- Eben Eyong --- Háland --- Herbehereak --- Herbehereetako Erresumaren --- Hò-làn --- Holand --- Holanda --- Holandija --- Holandska --- Hōlani --- Holenda --- Holland --- Holland Királyság --- Hollandi --- Hollandia --- Hōrana --- Huēyitlahtohcāyōtl in Tlanitlālpan --- Huland --- Hulanda --- Iseldiroedd --- Iseldiryow --- Ísiltír --- Izelvroio --- Karaleŭstva Nidėrlandy --- Katō Chōres --- Kē-tē-kok --- Keninkryk fan 'e Nederlannen --- Kerajaan Landa --- Kéyah Wóyahgo Siʼánígí --- Keyatiya Nederlandan --- Kingdom of the Netherlands --- Koninkrijk der Nederlanden --- Konungsríkið Holland --- Kraljevina Holandija --- Kralojstwo Nederlandow --- Kralstvo Holandija --- Kralstvo Niderlandii͡ --- Landa --- Madalmaad --- Mamlakat Hūland --- Mamlekhet Artsot ha-Shefelah --- Nederilande --- Nederlaand --- Nederlân --- Nederland --- Nederlande --- Nederlandene --- Nederlandia --- Nederlando --- Nederlands --- Néderlandzk --- Nederlatt --- Nederlendin Nutg --- Nedŏlland --- Neerlande --- Nethiland --- Niadaland --- Niderland --- Niderland Krallığı --- Niderlanddar --- Niderlande --- Nīderlandeja --- Nīderlandes Karaliste --- Niderlandʺi͡as --- Niderlandʺi͡as Korolʹuv --- Niderlandii͡ --- Niderlandla --- Niderlandlany Korolevstvosu --- Niderlandsem --- Niderlandsen Patshalăkh --- Niderlandtæ --- Niderlandtar --- Niderlandtar Korollege --- Niderlandty Kʺarolad --- Niderlandy --- Niderlandyn Vant Uls --- Niðurlond --- Niederlande --- Nirlan --- Nižozemska --- Nizozemsko --- Nyderlandai --- Nyderlandų Karalyst --- Olanda --- Ollandia --- Oostenrijkse Nederlanden --- Oranda --- Oranda Ōkoku --- Ot͡si͡azorksshi Nederlatt --- Paes Bass --- Paesi Bassi --- Paîs Bas --- Pais Basse --- Países Baixos --- Países Bajos --- Países Baxos --- Paisis Bajus --- Països Baixos --- Paixi Basci --- Pajjiżi l-Baxxi --- Payis-Bâs --- Payises Bashos --- Pays-Bas --- Pays-Bas autrichiens --- Pays-Bas espagnols --- Pays-Bas méridionaux --- Peyiba --- Reeriaght ny Çheer Injil --- Reĝlando Nederlando --- Regni Nederlandiarum --- Regno del Paises Basse --- Regnu di i Paesi Bassi --- Reino di Hulanda --- Reino dos Países Baixos --- Ríocht na hÍsiltíre --- Royaume des Pays-Bas --- Southern Netherlands --- Spanish Netherlands --- The Netherlands --- Tìrean Ìsle --- Tlanitlālpan --- Ubuholandi --- Ubuhorandi --- Ufalme wa Nchi za Chini --- Uholanzi --- Ulanda --- Ulanna --- Vasileio tōn Katō Chōrōn --- Walanda --- Zuidelijke Nederlanden

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