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2023 (2)

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Book
Global Perspectives on Precision Medicine
Authors: ---
ISBN: 9783031285936 Year: 2023 Publisher: Cham Springer International Publishing :Imprint: Springer

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Abstract

This book presents the promises of Precision Medicine (PM) and the challenges of its implementation in daily clinical routine, while addressing the anticipated ethical and social implications. It is the first book that critically analyzes the potential and the dilemmas relevant to genomics and precision medicine from healthcare, public health and global perspectives. The nine chapters presented in this book elaborate on pharmacogenomics' crucial role in maximizing the potential benefits and minimizing medication's potential risks in groups of people, especially in cancer treatment and other health conditions. Infectious and non-communicable diseases (NCDs) are also discussed in this book by identifying challenges and ways to overcome them. Essential concepts are addressed, such as health-related benefits and harm to individuals and the broader community, including threats to individual privacy and autonomy, which warrant just distribution of scarce resources. The book also identifies and addresses the lack of competency in the healthcare workforce in the era of PM and discusses the path to laying the ethical foundation for the implementation of PM in healthcare organizations.

Keywords

Bioethics. --- Public health. --- Medicine, Preventive. --- Health promotion. --- Medical sciences. --- Public Health. --- Health Promotion and Disease Prevention. --- Health Sciences. --- Basic medical sciences --- Basic sciences, Medical --- Biomedical sciences --- Health sciences --- Preclinical sciences --- Sciences, Medical --- Life sciences --- Medicine --- Health promotion programs --- Health promotion services --- Promotion of health --- Wellness programs --- Preventive health services --- Health education --- Disease prevention --- Diseases --- Prevention of disease --- Preventive medicine --- Pathology --- Preventive medicine physicians --- Public health --- Community health --- Health services --- Hygiene, Public --- Hygiene, Social --- Public health services --- Public hygiene --- Social hygiene --- Health --- Human services --- Biosecurity --- Health literacy --- Medicine, Preventive --- National health services --- Sanitation --- Biology --- Biomedical ethics --- Life sciences ethics --- Science --- Prevention --- Moral and ethical aspects --- Pharmacogenomics. --- Genomes --- Pharmacogenetics --- Effect of drugs on --- Precision Medicine. --- Pharmacogenomic Variants. --- Biomedical Ethics --- Health Care Ethics --- Ethics, Biomedical --- Ethics, Health Care --- Ethics, Medical --- Ethicists --- Pharmacogenetic Variants --- Pharmacokinetic Genetic Variants --- Genetic Variant, Pharmacokinetic --- Genetic Variants, Pharmacokinetic --- Pharmacogenetic Variant --- Pharmacogenomic Variant --- Pharmacokinetic Genetic Variant --- Variant, Pharmacogenetic --- Variant, Pharmacogenomic --- Variants, Pharmacogenetic --- Variants, Pharmacogenomic --- Precision Medicine --- P Health --- P-Health --- Personalized Medicine --- Theranostics --- Individualized Medicine --- Predictive Medicine --- Medicine, Individualized --- Medicine, Personalized --- Medicine, Precision --- Medicine, Predictive --- Theranostic --- Pharmacogenomic Variants --- Patient-Specific Modeling


Book
Oncology: Genomics, Precision Medicine and Therapeutic Targets
Authors: ---
ISBN: 9819915295 9819915287 Year: 2023 Publisher: Singapore : Springer Nature Singapore : Imprint: Springer,

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Abstract

This book describes translational cancer therapeutics and the way forward from clinical and molecular diagnosis to treatment. In addition, genomics alterations, microRNAs, and long non-coding RNAs translate precision medicine for the individualistic therapy of cancer patients. It describes the involvement of various pharmacogenetic factors in pharmacodynamic/pharmacokinetic (PD/PK) modulations of medicines. Indeed, the role of bioinformatics and biostatistics, considering the extensive data analysis serving precision medicine approaches, has also been entertained in the present book. Therefore, intended book demonstrates the successful medical evidence for the use of precision medicine in the treatment of cancer and its future clinical perspectives. It fills the gaps in cancer biology and precision medicine with its up-to-date content and well-designed chapters. It will serve as a valuable resource for science, medical students, and interdisciplinary researchers. It is a very welcome addition for the scientific community, research centers, and university-industry research collaborators to find out a complete capsular package about cancer drug targets, precision, and personalized medicine (including an introduction to cancer cell signaling, genomic alterations, miRNA targeting, pharmacogenetics, biomarkers, and metabolomics in precision medicine, etc.) at a single platform.

Keywords

Precision Medicine. --- Pharmacogenetics. --- Pharmacogenomic Variants. --- MicroRNAs --- RNA, Long Noncoding. --- Biomarkers. --- Neoplasms --- Medical Oncology. --- therapy. --- Clinical Oncology --- Oncology, Medical --- Oncology, Clinical --- Biochemical Marker --- Biologic Marker --- Biologic Markers --- Clinical Marker --- Immune Marker --- Immune Markers --- Immunologic Marker --- Laboratory Marker --- Marker, Biochemical --- Marker, Biological --- Marker, Clinical --- Marker, Immunologic --- Marker, Laboratory --- Marker, Serum --- Marker, Surrogate --- Serum Marker --- Surrogate End Point --- Surrogate End Points --- Surrogate Endpoint --- Surrogate Endpoints --- Surrogate Marker --- Viral Marker --- Biochemical Markers --- Biological Markers --- Biomarker --- Clinical Markers --- Immunologic Markers --- Laboratory Markers --- Markers, Biochemical --- Markers, Biological --- Markers, Clinical --- Markers, Immunologic --- Markers, Laboratory --- Markers, Serum --- Markers, Surrogate --- Markers, Viral --- Serum Markers --- Surrogate Markers --- Viral Markers --- Biological Marker --- End Point, Surrogate --- End Points, Surrogate --- Endpoint, Surrogate --- Endpoints, Surrogate --- Marker, Biologic --- Marker, Immune --- Marker, Viral --- Markers, Biologic --- Markers, Immune --- Molecular Probes --- Endophenotypes --- LINC RNA --- LincRNAs --- Long Intergenic Non-Protein Coding RNA --- Long Non-Coding RNA --- Long Non-Protein-Coding RNA --- Long Noncoding RNA --- Long ncRNA --- Long ncRNAs --- RNA, Long Non-Translated --- lncRNA --- LincRNA --- RNA, Long Untranslated --- Long Intergenic Non Protein Coding RNA --- Long Non Coding RNA --- Long Non Protein Coding RNA --- Long Non-Translated RNA --- Long Untranslated RNA --- Non-Coding RNA, Long --- Non-Protein-Coding RNA, Long --- Non-Translated RNA, Long --- Noncoding RNA, Long --- RNA, Long Non Translated --- RNA, Long Non-Coding --- RNA, Long Non-Protein-Coding --- Untranslated RNA, Long --- ncRNA, Long --- ncRNAs, Long --- Micro RNA --- MicroRNA --- Primary MicroRNA --- Primary miRNA --- miRNAs --- pre-miRNA --- pri-miRNA --- RNA, Small Temporal --- Small Temporal RNA --- miRNA --- stRNA --- MicroRNA, Primary --- RNA, Micro --- Temporal RNA, Small --- miRNA, Primary --- pre miRNA --- pri miRNA --- RNA, Small Interfering --- Pharmacogenetic Variants --- Pharmacokinetic Genetic Variants --- Genetic Variant, Pharmacokinetic --- Genetic Variants, Pharmacokinetic --- Pharmacogenetic Variant --- Pharmacogenomic Variant --- Pharmacokinetic Genetic Variant --- Variant, Pharmacogenetic --- Variant, Pharmacogenomic --- Variants, Pharmacogenetic --- Variants, Pharmacogenomic --- Pharmacogenetics --- Precision Medicine --- P Health --- P-Health --- Personalized Medicine --- Theranostics --- Individualized Medicine --- Predictive Medicine --- Medicine, Individualized --- Medicine, Personalized --- Medicine, Precision --- Medicine, Predictive --- Theranostic --- Pharmacogenomic Variants --- Patient-Specific Modeling --- Pharmacogenomics --- Drug Resistance --- Toxicology --- Cancer. --- Cancer—Genetic aspects. --- Oncology. --- Therapeutics. --- Cancer Biology. --- Cancer Genetics and Genomics. --- Medical treatment --- Therapy --- Treatment of diseases --- Treatments for diseases --- Clinical medicine --- Tumors --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors

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