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Dissertation
Contribution à l'étude des effets du facteur de croissance épidermique, EGF, sur les cellules mésenchymateuses
Author:
Year: 1990 Publisher: Liège : Université de Liège. Faculté de médecine (ULg). Département de clinique et pathologie médicales,


Dissertation
Etude des effets de facteurs de croissance sur des chondrocytes humains cultivés à trois dimensions
Author:
Year: 1987 Publisher: Liège : Université de Liège. Faculté de médecine (ULg). Département de clinique et pathologie médicales,

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Dissertation
Chondrocytes articulaires humains en culture tridimensionnelle et synoviocytes humains en culture bidimensionnelle : étude des effets de certaines lymphokines et monokines
Author:
Year: 1987 Publisher: Liège : Université de Liège. Faculté de médecine (ULg). Département de clinique et pathologie médicales,

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Epidermal growth factors and cytokines
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ISBN: 0824791029 9780824791025 Year: 1994 Publisher: New York Marcel Dekker


Book
Third-Generation EGFR Inhibitors
Authors: --- ---
ISBN: 0081026625 0081026617 9780081026625 9780081026618 Year: 2019 Publisher: Amsterdam

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Book
Fast Facts : EGFR Exon 20 Insertion Mutations in NSCLC
Authors: --- --- ---
ISBN: 3318071366 Year: 2022 Publisher: Abingdon, Oxford : S. Karger AG,

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Abstract

Lung cancer is still a major cause of death globally, but the development of personalized, precision medicine has had a marked effect on treatment management and improved clinical outcomes, particularly for those with advanced stage non-small-cell lung cancer (NSCLC). EGFR mutations are the third most common mutation found in patients with advanced stage NSCLC. First-line treatment with a traditional epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI) is indicated for most patients, but not for patients with EGFR exon 20 insertion mutations (ex20ins). Instead, recent approvals of an EGFR ex20ins-specific TKI (mobocertinib) and a bispecific antibody (amivantamab) targeting both EGFR and mesenchymalepithelial transition factor (MET) offer the potential for improved outcomes in this patient population. Furthermore, new approaches to treatment continue to be developed and trials for new agents with greater activity against ex20ins mutations are ongoing.


Book
Les thérapies ciblées
Authors: --- ---
ISBN: 9782287360077 2287360077 9782287360084 9786611960261 1281960268 2287360085 Year: 2008 Publisher: Paris Springer Paris

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En 2008, les progrès des connaissances en matière de la carcinogenèse ont permis d'identifier des cibles moléculaires clés dans la genèse de nombreuses tumeurs solides. Bien que non exhaustives encore, ces informations permettent l'utilisation de composés dirigés contre les cibles moléculaires, spécifiquement activées dans les cancers donnant ainsi naissance au concept de thérapie ciblée. Le trastuzumab, dirigé contre HER2 dont le gène est amplifié dans 20 % des adénocarcinomes du sein, et l'imatinib, inhibiteur de kinase dirigé contre la protéine de fusion bcr/abl, issu de la t(9,22) des leuc


Dissertation
Etude expérimentale de la synoviale articulaire humaine en culture in vitro
Author:
Year: 1987 Publisher: Liège : Université de Liège. Faculté de médecine (ULg). Département de clinique et pathologie médicales,


Book
Molecular neuro-oncology and its impact on the clinical management of brain tumors
Authors: --- ---
ISBN: 3540573518 3642850413 3642850391 Year: 1994 Volume: 135 Publisher: Berlin : Springer-Verlag,


Book
Guide to Targeted Therapies: EGFR mutations in NSCLC
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ISBN: 3319030590 3319030582 Year: 2014 Publisher: Cham : Springer International Publishing : Imprint: Adis,

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Guide to Targeted Therapies: EGFR Mutations in NSCLC is a speedy and up-to-date review, which discusses EGFR mutations, testing methods and technology, current and emerging therapies, and resources that clinicians can provide to their patients. Busy healthcare professionals who want a quick review of EGFR gene mutations as well as a summary of current therapies will benefit from this succinct guide.

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