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This book describes the science, development, properties and application of of ultra-high molecular weight polyethylene (UHMWPE) used in artificial joints. This material is currently used in 1.4 million patients around the world every year for use in the hip, knee, upper extremities, and spine. Since the publication of the 1st edition there have been major advances in the development and clinical adoption of highly crosslinked UHMWPE for hip and knee replacement. There has also been a major international effort to introduce Vitamin E stabilized UHMWPE for patients. The accumulated know
Ultrahigh molecular weight polyethylene. --- Plastics in medicine. --- Artificial joints. --- Joint prostheses --- Joints, Artificial --- Prosthetic joints --- Total joint replacement --- Orthopedic implants --- Prosthesis --- Polymers in medicine --- High modulus polyethylene --- High performance polyethylene --- HMPE (High modulus polyethylene) --- HPPE (High performance polyethylene) --- UHMPE (Ultrahigh molecular mass polyethylene) --- UHMWPE (Ultrahigh molecular weight polyethylene) --- Ultra-high molecular weight polyethylene --- Ultrahigh molecular mass polyethylene --- Polyethylene
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Joint replacement is a very successful medical treatment. However, the survivorship of the implants could be adversely affected due to the loss of materials in the form of particles or ions as the bearing surfaces articulate against earch other. The consequent tissue and immune response to the wear products, remain one of the key factors of their failure. Tribology has been defined as the science and technology of interacting surfaces in relative motion and all related wear products (e.g., particles, ions, etc.). Over the last few decades, in an attempt to understand and improve joint replacement technology, the tribological performance of several material combinations have been studied experimentally and assessed clinically. In addition, research has focused on the biological effects and long term consequences of wear products. Improvements have been made in manufacturing processes, precision engineering capabilities, device designs and materials properties in order to minimize wear and friction and maximize component longevity in vivo.
alginate --- biotribology --- multiwall carbon nanotubes --- arthroplasty --- validated model --- implant --- lubrication --- fillers --- ion treatment --- biomechanical testing/analysis --- titanium niobium nitride --- orthopedic --- UHMWPE --- wear testing --- wear resistance --- wear debris --- biomaterials --- biolubricant --- wear simulation --- surface engineering --- degenerative disc disease --- total disc replacement --- joint simulators --- crosslinked polyethylene --- TKA --- unicompartmental arthroplasty --- implants --- mechanical properties --- pin-on-plate --- ultra-high molecular weight polyethylene --- hip implants --- failure --- highly crosslinked UHMWPE --- gamma irradiation --- hip joint simulator --- oxidized zirconium --- osteolysis --- histomorphological characterization --- cross-linked polyethylene --- wear --- hip prosthesis --- cobalt --- abrasion --- metal-on-metal --- synovial lining --- wear debris cytotoxicity --- alternative bearings --- surfaces --- polyethylene wear --- knee replacement --- patello-femoral joint --- crosslink density --- FEA --- coating --- ultra high molecular weight polyethylene --- contact angle --- finite element analysis --- systematic review --- wear analysis/testing --- knee --- in vitro macrophages response --- synovial fluid --- gellan gum
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Recently, the orthopedic industry developed new processing techniques (radiation crosslinking), which are expected to dramatically reduce wear and improve the longevity of hip implants beyond 10 years.This book describes the history and properties of ultra-high molecular weight polyethylene (UHMWPE) used in artificial joints by describing its properties and reviewing the latest clinical results.* The most up-to-date information on the properties of UHMWPE* Endorsed by Ticona - the world's leading manufacturer of UHMWPE for medical use* An enormous 'installed bas
Artificial joints. --- Plastics in medicine. --- Polyethylene. --- Polyethylene - Therapeutic use. --- Polyethylene--Therapeutic use. --- Artificial joints --- Ultrahigh molecular weight polyethylene --- Plastics in medicine --- Prostheses and Implants --- Polyethylene --- Joints --- Skeleton --- Equipment and Supplies --- Polyethylenes --- Musculoskeletal System --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Plastics --- Polyenes --- Polymers --- Alkenes --- Anatomy --- Macromolecular Substances --- Biomedical and Dental Materials --- Hydrocarbons, Acyclic --- Chemicals and Drugs --- Manufactured Materials --- Hydrocarbons --- Technology, Industry, and Agriculture --- Organic Chemicals --- Technology, Industry, Agriculture --- Surgery - General and By Type --- Surgery & Anesthesiology --- Health & Biological Sciences --- Therapeutic use --- Therapeutic use. --- High modulus polyethylene --- High performance polyethylene --- HMPE (High modulus polyethylene) --- HPPE (High performance polyethylene) --- UHMPE (Ultrahigh molecular mass polyethylene) --- UHMWPE (Ultrahigh molecular weight polyethylene) --- Ultra-high molecular weight polyethylene --- Ultrahigh molecular mass polyethylene --- Joint prostheses --- Joints, Artificial --- Prosthetic joints --- Total joint replacement --- Polymers in medicine --- Orthopedic implants --- Prosthesis
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This book covers a wide range of topics in the orthopaedic fields and can be used as a textbook for the final undergraduate engineering course or as a topic on tribology at the postgraduate level. This book can serve as a useful reference for academics, tribology, and materials researchers; mechanical, materials, and physics engineers; biomedical scientists and professionals in tribology; and related industries. The scientific interest in this book will be evident for many important centres of research, including laboratories and universities throughout the world.
History of engineering & technology --- vitamin-E stabilized PE --- cross-linked PE --- standard PE --- hip simulator --- FTIR analysis --- Ti-28Nb-35.4 alloy --- powder metallurgy --- ball milling --- mechanical properties --- biocompatibility --- total hip arthroplasty --- musculoskeletal multibody model --- dynamic loading --- finite element analysis --- radial clearance --- dry and wet friction --- digital image correlation --- homogeneous strain --- small deformation level --- accuracy --- precision --- calcium phosphate cements --- polarization --- CoCr alloy --- wear particles --- hyaluronic acid --- macrophages biocompatibility --- UHMWPE --- tribology --- h-index --- bibliometric indicators --- biomaterials --- quality of research --- citations --- ceramic --- friction --- hip --- implants --- polyethylene --- prosthesis --- simulator --- wear --- mandible condylar fractures --- surgical treatment --- titanium --- PLLA --- Selective Laser Melting --- Direct Metal Laser Sintering --- porosity --- titanium alloys --- yield strength --- ultimate tensile strength --- X-Ray Diffraction --- n/a --- computational model --- biomechanics --- unicompartmental knee replacement --- CFR-PEEK --- varus and valgus alignments --- bioceramics --- additive manufacturing --- scaffolds --- bone tissue engineering
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This book covers a wide range of topics in the orthopaedic fields and can be used as a textbook for the final undergraduate engineering course or as a topic on tribology at the postgraduate level. This book can serve as a useful reference for academics, tribology, and materials researchers; mechanical, materials, and physics engineers; biomedical scientists and professionals in tribology; and related industries. The scientific interest in this book will be evident for many important centres of research, including laboratories and universities throughout the world.
History of engineering & technology --- vitamin-E stabilized PE --- cross-linked PE --- standard PE --- hip simulator --- FTIR analysis --- Ti-28Nb-35.4 alloy --- powder metallurgy --- ball milling --- mechanical properties --- biocompatibility --- total hip arthroplasty --- musculoskeletal multibody model --- dynamic loading --- finite element analysis --- radial clearance --- dry and wet friction --- digital image correlation --- homogeneous strain --- small deformation level --- accuracy --- precision --- calcium phosphate cements --- polarization --- CoCr alloy --- wear particles --- hyaluronic acid --- macrophages biocompatibility --- UHMWPE --- tribology --- h-index --- bibliometric indicators --- biomaterials --- quality of research --- citations --- ceramic --- friction --- hip --- implants --- polyethylene --- prosthesis --- simulator --- wear --- mandible condylar fractures --- surgical treatment --- titanium --- PLLA --- Selective Laser Melting --- Direct Metal Laser Sintering --- porosity --- titanium alloys --- yield strength --- ultimate tensile strength --- X-Ray Diffraction --- n/a --- computational model --- biomechanics --- unicompartmental knee replacement --- CFR-PEEK --- varus and valgus alignments --- bioceramics --- additive manufacturing --- scaffolds --- bone tissue engineering
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This book covers a wide range of topics in the orthopaedic fields and can be used as a textbook for the final undergraduate engineering course or as a topic on tribology at the postgraduate level. This book can serve as a useful reference for academics, tribology, and materials researchers; mechanical, materials, and physics engineers; biomedical scientists and professionals in tribology; and related industries. The scientific interest in this book will be evident for many important centres of research, including laboratories and universities throughout the world.
vitamin-E stabilized PE --- cross-linked PE --- standard PE --- hip simulator --- FTIR analysis --- Ti-28Nb-35.4 alloy --- powder metallurgy --- ball milling --- mechanical properties --- biocompatibility --- total hip arthroplasty --- musculoskeletal multibody model --- dynamic loading --- finite element analysis --- radial clearance --- dry and wet friction --- digital image correlation --- homogeneous strain --- small deformation level --- accuracy --- precision --- calcium phosphate cements --- polarization --- CoCr alloy --- wear particles --- hyaluronic acid --- macrophages biocompatibility --- UHMWPE --- tribology --- h-index --- bibliometric indicators --- biomaterials --- quality of research --- citations --- ceramic --- friction --- hip --- implants --- polyethylene --- prosthesis --- simulator --- wear --- mandible condylar fractures --- surgical treatment --- titanium --- PLLA --- Selective Laser Melting --- Direct Metal Laser Sintering --- porosity --- titanium alloys --- yield strength --- ultimate tensile strength --- X-Ray Diffraction --- n/a --- computational model --- biomechanics --- unicompartmental knee replacement --- CFR-PEEK --- varus and valgus alignments --- bioceramics --- additive manufacturing --- scaffolds --- bone tissue engineering
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This collection of research and review papers is aimed at depicting the state of the art on the possible correlations between processing variables, obtained structure and special properties which this structure induces on the plastic part. The extraordinary capacity of plastics to modify their properties according to a particular structure is evidenced for several transformation processes and for many applications. The final common goal is to take profit of this peculiar capacity of plastics by inducing, through a suitable processing, a specific spatial organization.
polymer blend --- carbon nanotube --- polycaprolactone --- X-ray diffraction --- reactive blending --- copper clad laminate --- incremental forming --- uniaxial compression --- fatigue --- nanoparticles --- composite --- deformation --- polymer composite --- humidity --- model --- uniaxial tensile deformation --- injection molding --- SPIF --- bioresorbable polymers --- flow --- poly(ethylene terephthalate) --- morphology --- 3D printing/additive manufacturing --- supercritical CO2 --- polymer morphology --- tissue engineering and regenerative medicine --- microfibrillar composites --- polyamide 6 --- ultra-high molecular weight polyethylene --- chain orientation --- processing --- intrinsic viscosity --- conductive polymer composites --- microcellular injection molding --- ionic liquids --- poly(?-caprolactone) --- biaxial elongation --- biobased films --- crystalline morphology --- gel --- composites --- PLLA --- bioresorbable vascular scaffolds --- temperature --- layered double hydroxides --- epoxy microstructure --- nanoreinforcement --- shear --- collagen --- controllable gas permeability --- contact angle --- WAXS --- mechanical performance --- biodegradable nanofibers --- in situ X-ray --- foam --- polyolefin --- carbon black --- polymorphism --- degradation --- polypropylene --- XRD --- graphite --- polyimide film --- indentation --- ultra-high molecular weight polyethylene (UHMWPE) --- mold temperature evolution --- fused filament fabrication/fused deposition modelling --- polyvinyl butyral --- supercritical fluid --- conductive filler --- octakis[(3-glycidoxypropyl)dimethylsiloxy]octasilsesquioxane (GPOSS) --- supercritical N2 --- compression molding --- flame retardant --- epinephrine --- crystallinity --- ethylene vinyl acetate --- atomic force microscopy --- temperature sensitive --- mechanical properties --- crystallisation --- microencapsulation --- linear coefficient of thermal expansion (CTE) --- structure and properties --- PLA --- isotactic polypropylene --- lidocaine --- graphene --- structural analysis --- critical gel --- Harmonix AFM --- physicochemical characterization --- polyurethane --- cavitation --- curing rate --- orientation --- breathable film --- stress-induced phase transitions --- phase transitions --- SAXS --- hydrophobicity --- melamine polyphosphate --- PLGA --- compatibilizer --- polyoxymethylene (POM) --- homogeneous dispersion --- stretch blow molding --- electrical conductivity --- poly(lactic acid)
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Polymer science and technology in Italy represent long-lasting and interdisciplinary fields in which chemistry, physics, and engineering mix together to produce studies which are considered among the best in the world. Several research groups coming from very different fields often collaborate in the design of the material, of the part, and of the processing technology to obtain innovative products with outstanding, new, and smart properties. Examples of the contributions of Italian research in the field are featured in top journals and conferences throughout the world. This Special Issue collects an overview of polymer science and technology in Italy. The research topics include: polymer composites and nanocomposites; biodegradable polymers; polymers with special properties and smart polymers; advanced characterization of polymers; new and innovative polymer processes; modeling of polymer processing; polymeric materials in additive manufacturing; process–properties relationships; polymeric parts for special applications.
Research & information: general --- polyhedral oligomeric silsesquioxanes --- nanocomposites --- POSS --- polystyrene --- thermal behavior --- SEM analysis --- soy flour --- soy protein isolate --- insoluble carbohydrates --- periodate oxidation --- aldehydes generation --- condensation reactions --- soy adhesives --- biodegradable polymers --- rheological properties --- irrigation pipes --- soil burial test --- polyesters --- Bio-Flex® --- Mater-Bi® --- polymer degradation --- photo-oxidation --- pectin --- alginate --- biocomposites --- food packaging --- degradable films --- ionic liquids --- 3D printing --- digital light processing --- CO2 capture --- furanic polymer --- spectroscopy --- solid-state 13C-NMR --- FTIR --- Raman --- linear structure --- ring opening --- γ-lactone --- Diels-Alder --- SAS coprecipitation --- controlled drug delivery systems --- microparticles --- eudragit --- supercritical carbon dioxide --- dental materials --- composite resin --- layered double hydroxide --- calcium bentonite --- antibiofilm activity --- injection molding --- structure/properties relationship --- cavity temperature fast modulation --- chitosan --- cyclodextrin --- macromolecular complex --- dalargin --- enkephalin --- chymotrypsin --- NMR --- oral peptide delivery --- peptide stability --- cold-cure --- epoxy resins --- organic-inorganic hybrids --- sol-gel --- layered double hydroxides --- carbon nanotubes --- electrical properties --- polyphenols --- flavonoids --- furanics --- sulphur --- bio-polymers --- pentane --- heating value --- mulch films --- Ecovio® --- polylactide --- poly(butyleneadipate-co-butyleneterephtalate) --- polyethylene --- polymer melt --- primary and secondary relaxations --- Johari-Goldstein relaxation --- bond reorientation --- vibrational dynamics --- molecular-dynamics simulations --- UV-LED curing --- epoxy-acrylate resin --- biochar --- multiwalled carbon nanotubes --- composites --- reduced graphene oxide --- polyketone functionalization --- electrically-conductive nanocomposites --- UHMWPE --- wear tests --- bio-activity --- history --- cyclodextrin nanosponge --- crosslinked polymer --- diclofenac --- mefenamic acid --- molecular imprinting --- delayed addition --- binding isotherm --- binding selectivity --- imprinting factor --- polymers --- life cycle assessment --- polymeric materials --- sustainability --- plastic --- LCA --- additive manufacturing --- LCD printing --- epoxy --- polymer blends --- thermomechanical properties --- n/a
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Polymer science and technology in Italy represent long-lasting and interdisciplinary fields in which chemistry, physics, and engineering mix together to produce studies which are considered among the best in the world. Several research groups coming from very different fields often collaborate in the design of the material, of the part, and of the processing technology to obtain innovative products with outstanding, new, and smart properties. Examples of the contributions of Italian research in the field are featured in top journals and conferences throughout the world. This Special Issue collects an overview of polymer science and technology in Italy. The research topics include: polymer composites and nanocomposites; biodegradable polymers; polymers with special properties and smart polymers; advanced characterization of polymers; new and innovative polymer processes; modeling of polymer processing; polymeric materials in additive manufacturing; process–properties relationships; polymeric parts for special applications.
polyhedral oligomeric silsesquioxanes --- nanocomposites --- POSS --- polystyrene --- thermal behavior --- SEM analysis --- soy flour --- soy protein isolate --- insoluble carbohydrates --- periodate oxidation --- aldehydes generation --- condensation reactions --- soy adhesives --- biodegradable polymers --- rheological properties --- irrigation pipes --- soil burial test --- polyesters --- Bio-Flex® --- Mater-Bi® --- polymer degradation --- photo-oxidation --- pectin --- alginate --- biocomposites --- food packaging --- degradable films --- ionic liquids --- 3D printing --- digital light processing --- CO2 capture --- furanic polymer --- spectroscopy --- solid-state 13C-NMR --- FTIR --- Raman --- linear structure --- ring opening --- γ-lactone --- Diels-Alder --- SAS coprecipitation --- controlled drug delivery systems --- microparticles --- eudragit --- supercritical carbon dioxide --- dental materials --- composite resin --- layered double hydroxide --- calcium bentonite --- antibiofilm activity --- injection molding --- structure/properties relationship --- cavity temperature fast modulation --- chitosan --- cyclodextrin --- macromolecular complex --- dalargin --- enkephalin --- chymotrypsin --- NMR --- oral peptide delivery --- peptide stability --- cold-cure --- epoxy resins --- organic-inorganic hybrids --- sol-gel --- layered double hydroxides --- carbon nanotubes --- electrical properties --- polyphenols --- flavonoids --- furanics --- sulphur --- bio-polymers --- pentane --- heating value --- mulch films --- Ecovio® --- polylactide --- poly(butyleneadipate-co-butyleneterephtalate) --- polyethylene --- polymer melt --- primary and secondary relaxations --- Johari-Goldstein relaxation --- bond reorientation --- vibrational dynamics --- molecular-dynamics simulations --- UV-LED curing --- epoxy-acrylate resin --- biochar --- multiwalled carbon nanotubes --- composites --- reduced graphene oxide --- polyketone functionalization --- electrically-conductive nanocomposites --- UHMWPE --- wear tests --- bio-activity --- history --- cyclodextrin nanosponge --- crosslinked polymer --- diclofenac --- mefenamic acid --- molecular imprinting --- delayed addition --- binding isotherm --- binding selectivity --- imprinting factor --- polymers --- life cycle assessment --- polymeric materials --- sustainability --- plastic --- LCA --- additive manufacturing --- LCD printing --- epoxy --- polymer blends --- thermomechanical properties --- n/a
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Joint replacement is a very successful medical treatment. However, the survivorship of hip, knee, shoulder, and other implants is limited. The degradation of materials and the immune response against degradation products or an altered tissue loading condition as well as infections remain key factors of their failure. Current research in biomechanics and biomaterials is trying to overcome these existing limitations. This includes new implant designs and materials, bearings concepts and tribology, kinematical concepts, surgical techniques, and anti-inflammatory and infection prevention strategies. A careful evaluation of new materials and concepts is required in order to fully assess the strengths and weaknesses and to improve the quality and outcomes of joint replacements. Therefore, extensive research and clinical trials are essential. The main aspects that are addressed in this Special Issue are related to new material, design and manufacturing considerations of implants, implant wear and its potential clinical consequence, implant fixation, infection-related material aspects, and taper-related research topics. This Special Issue gives an overview of the ongoing research in those fields. The contributions were solicited from researchers working in the fields of biomechanics, biomaterials, and bio- and tissue-engineering.
Information technology industries --- electrocautery --- titanium alloy --- cobalt-chrome alloy --- fatigue behavior --- biomechanical study --- Vertebral body replacement (VBR) --- non metallic --- radiolucent --- CF/PEEK --- biomechanics --- tumor --- vertebral fracture --- spine --- calcium phosphate --- granules --- bone graft substitutes --- total hip arthroplasty --- implant deformation --- acetabulum --- Metasul --- 28 mm small head --- metal-on-metal THA --- cobalt --- chromium --- titanium --- blood metal ions --- inflammation --- cytokines --- metal particles --- metal ions --- synovium --- dual taper modular hip stem --- acetabular revision --- asymptomatic stem modularity --- decision making model --- threshold --- biomaterials --- arthroplasty --- orthopaedic tribology --- experimental simulation --- total knee replacement --- PEEK-OPTIMA™ --- UHMWPE --- third body wear --- modular acetabular cup --- poly-ether-ether-ketone (PEEK) --- ceramics --- ultra-high-molecular-weight polyethylene (UHMW-PE) --- strain distribution --- bone stock --- cup-inlay stability --- disassembly forces --- relative motion --- periprosthetic joint infections --- infection prophylaxis --- Staphylococcus epidermidis --- in vivo osteomyelitis model --- metal wear --- retrieval study --- metal-on-metal articulation --- volumetric wear --- megaendoprosthesis --- total knee arthroplasty --- bone tumor --- Roentgen stereophotogrammetric analysis --- hip arthroplasty --- elementary geometrical shape model --- interchangeability --- head–taper junction --- migration --- ion implantation --- precision casting --- Ti6Al4V --- calcium --- phosphorus --- centrifugal casting --- porous implants --- tantalum --- hip replacement --- revision hip arthroplasty --- primary stability --- backside wear --- cross-linked --- total hip replacement --- hip cup system --- composite --- fibers --- polycarbonate-urethane --- meniscal replacement --- mechanical properties --- meniscus --- silicon nitride --- coating --- joint replacement --- wear --- adhesion --- trunnionosis --- trunnion failure --- fretting corrosion --- head–neck junction --- mechanically assisted crevice corrosion --- implant --- biomaterial --- corrosion --- residual stress --- taper connection --- anodic polarization --- surface treatment --- knee joint --- patellar component --- musculoskeletal multibody simulation --- patellofemoral joint --- polyetheretherketone --- fixation --- debonding --- implant–cement interface --- PMMA --- periprosthetic joint infection --- cement spacer --- articulating spacer --- hip spacer --- two-stage revision --- surface alteration --- surface roughness --- third-body wear --- zirconium oxide particles --- metal-on-cement articulation --- oxford unicompartmental knee arthroplasty --- bearing thickness --- retrieval analysis --- n/a --- biomedical rheology --- viscosity --- bovine calf serum --- shear thinning --- numerical simulation --- head-taper junction --- head-neck junction --- implant-cement interface
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