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Dissertation
Modifications expérimentales de la mélanogenèse, un caractère de différenciation d'une souche de mélanomes en culture
Author:
Year: 1983 Publisher: Liège : Université de Liège. Faculté de Médecine. Institut supérieur d'éducation physique,

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Abstract

Keywords

Melanin --- Melanoma --- Tyrosinase


Book
Problem of skin depigmentation in Rwanda : modulators of tyrosinase extracted from plants used in traditional medicine

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Dissertation
Contribution à l'étude phytochimique des espèces Leea Guinensis, Litchi Chinensis et Persea Americana en vue de valorisations cosmétiques
Authors: --- --- --- --- --- et al.
Year: 2017 Publisher: Liège Université de Liège (ULiège)

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Dans le cadre de la thèse de Saive M. concernant l’étude phytochimique de plantes mahoraise,&#13;l’étude approfondie de trois activités biologiques sur trois extraits végétaux a été réalisée. Les&#13;activités antityrosinase, antioxydante et anti-inflammatoire ont été sélectionnées compte tenu de leur&#13;intérêt pour la valorisation en cosmétique.&#13;Suite aux études préliminaires réalisées sur l’île Mayotte par Saive M., les feuilles de Persea&#13;americana Mill., les feuilles de Leea guineensis G. Don. et les racines de Litchi chinensis Sonn. ont&#13;été sélectionnées pour cette étude approfondie.&#13;L’étude des activités biologiques citées ci-dessus sur les différents organes végétaux sélectionnés&#13;a été réalisée en plusieurs étapes. Pour commencer, les échantillons ont subi des extractions par la&#13;technique du Soxhlet. Les extraits obtenus ont ensuite subi divers fractionnements par centrifugation&#13;et chromatographie liquide. Afin de tendre vers l’identification des molécules responsables des&#13;activités d’intérêt, les fractions les plus actives lors des mesures spectrophotométriques ont été&#13;sélectionnées tout au long des différentes étapes de fractionnement à l’aide de technique statistique.&#13;Cela a abouti à l’identification de fractions d’intérêt pour chacune des activités ciblées et&#13;l’obtention d’une molécule suffisamment pure pour entamer le travail d’étude structurale.


Book
Marine Microbial Diversity as a Source of Bioactive Natural Products
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Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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A trillion different microbial species have been evolving for some 3.5 billion years, producing ever more complex active secondary metabolites. The sea is a cauldron of a great diversity of useful and valuable compounds. This Special Issue focused on studies of marine microbe natural products for discovering compounds useful to humankind. Papers were collected that provide up-to-date information regarding the characterization of marine microbes’ metabolic diversity and the evaluation of the therapeutic potential of marine microbes’ metabolites. Most of the articles in this book deal with marine fungi, biological and chemical diversity, and their active metabolites. This may be a sign that marine fungi have been under studied to date and are perceived by many researchers as an important source of discovery in this field. A best practices guide for the isolation of marine fungi from different matrixes and their conservation is also presented. The comparison of the phylogenetic and metabolomic profiles of microalgae from different lineages provides novel insights into the potential of chemotaxonomy in marine phytoplankton, showing a good overlap of phylogenetic and chemotaxonomic signals.


Book
New Mechanisms of Action of Natural Antioxidants in Health and Disease
Authors: ---
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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This book contributes to increasing the knowledge on the mechanisms of action of natural antioxidants, evidencing their pleiotropic role in the prevention and/or counteraction of degenerative diseases, and promoting their application in the functional food and cosmetic fields.


Book
New Mechanisms of Action of Natural Antioxidants in Health and Disease
Authors: ---
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This book contributes to increasing the knowledge on the mechanisms of action of natural antioxidants, evidencing their pleiotropic role in the prevention and/or counteraction of degenerative diseases, and promoting their application in the functional food and cosmetic fields.


Book
New Mechanisms of Action of Natural Antioxidants in Health and Disease
Authors: ---
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

This book contributes to increasing the knowledge on the mechanisms of action of natural antioxidants, evidencing their pleiotropic role in the prevention and/or counteraction of degenerative diseases, and promoting their application in the functional food and cosmetic fields.


Book
Marine Microbial Diversity as a Source of Bioactive Natural Products
Author:
Year: 2020 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Abstract

A trillion different microbial species have been evolving for some 3.5 billion years, producing ever more complex active secondary metabolites. The sea is a cauldron of a great diversity of useful and valuable compounds. This Special Issue focused on studies of marine microbe natural products for discovering compounds useful to humankind. Papers were collected that provide up-to-date information regarding the characterization of marine microbes’ metabolic diversity and the evaluation of the therapeutic potential of marine microbes’ metabolites. Most of the articles in this book deal with marine fungi, biological and chemical diversity, and their active metabolites. This may be a sign that marine fungi have been under studied to date and are perceived by many researchers as an important source of discovery in this field. A best practices guide for the isolation of marine fungi from different matrixes and their conservation is also presented. The comparison of the phylogenetic and metabolomic profiles of microalgae from different lineages provides novel insights into the potential of chemotaxonomy in marine phytoplankton, showing a good overlap of phylogenetic and chemotaxonomic signals.


Book
Natural and Synthetic Bioactives for Skin Health, Disease and Management
Authors: --- ---
ISBN: 3036560688 303656067X Year: 2022 Publisher: Basel MDPI - Multidisciplinary Digital Publishing Institute

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In recent years, researchers have shown a special interest in natural products as alternative methods for the prevention, treatment, and/or management of various skin illnesses and disorders, primarily due to their natural availability, efficacity, reduced cost, and minimal toxicity. In a similar vein, synthetic bioactives, as well as small molecules, have been studied in vitro, in vivo, and in clinical studies as potential drugs or supplements. This Special Issue of Nutrients comprises an array of literature reviews, original communications, and studies on the roles of natural products, synthetic bioactives, and small molecules in a variety of skin disorders and diseases, such as aging, atopic dermatitis, cutaneous T-cell lymphomas, melanoma, allergies, hyperpigmentation, inflammation, and more, which were investigated through in vitro and ex vivo approaches, preclinical trials, cell-based assays, and animal models. The mechanisms of action of certain compounds are proposed, while others are currently under investigation. The authors of the papers also explore technologies designed to improve the bioavailability and delivery of certain compounds. In lieu of ongoing research on a variety of skin disorders, the wealth of information published in this Special Issue can act as a springboard for the development of new preventive and therapeutic modalities for the management of skin diseases.

Keywords

Research & information: general --- Biology, life sciences --- keratinocytes --- rutin --- ascorbic acid --- UV radiation --- proteomics --- 3D cell culture --- borage oil --- triacylglycerol metabolism --- acyl-ceramide --- corneocyte lipid envelope --- epidermis --- anti-melanogenesis --- B16/F10 melanoma cell --- hydroxyoctadecadienoic acid --- Sorghum bicolor --- 3-isobutyl-1-methylxanthine --- mycosis fungoides --- atopic dermatitis --- cutaneous lymphomas --- cornified envelope proteins --- FLG --- microalgae --- Planktochlorella nurekis --- skin cells --- proliferation --- senescence --- holothuroids --- glycosaminoglycans --- inflammation --- ear-inflammation --- whey --- Lactobacillus helveticus --- melanin --- α-melanocyte-stimulating hormone --- tyrosinase --- tyrosinase-related protein 1 --- dopachrome tautomerase --- microphthalmia-associated transcription factor --- cosmetics --- black cumin --- Nigella sativa --- Thymocid® --- skin aging --- glycation --- collagen --- collagenase --- elastase --- melanogenesis --- cosmeceutical --- konjac glucomannan --- ultraviolet B --- human epidermal primary melanocytes --- human embryonic fibroblasts --- anti-inflammatory activity --- antioxidant activity --- Cornus officinalis --- molecular docking --- human high-affinity IgE receptors --- α-MSH --- UVB irradiation --- lotus seedpod extract --- epigallocatechin --- propolis --- skin --- matrix metalloproteinase-1 --- UV --- phosphoinositide 3-kinase --- skin care --- skin health --- bioactive substances --- phytonutrients --- antioxidants --- nutraceuticals --- Perilla frutescens --- cell proliferation --- ultraviolet radiation --- DNA repair --- Lactobacillus plantarum CJLP55 --- acne vulgaris --- sebum --- hydration --- urine bacterial extracellular vesicles --- fungal infections --- nanohydrogel --- polysaccharide --- essential oils --- eggshell membrane --- keratinocyte differentiation --- TRPV --- skin thickness --- Lithospermum erythrorhizon --- NC/Nga --- Th1 --- Th2 --- Th17 --- Th22 --- immune balance --- skin barrier function --- n/a


Book
Natural Antioxidants: Innovative Extraction and Application in Foods
Authors: ---
Year: 2021 Publisher: Basel, Switzerland MDPI - Multidisciplinary Digital Publishing Institute

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Natural Antioxidants: Innovative Extraction and Application in Foods compiles comprehensive information and recent findings on the extraction of antioxidants from different natural resources and investigates their application in food. The book focuses on different sources of natural antioxidants such as the Hypochaeris and Hyoseris species, pomegranate seed oil, thyme, hemp, coriander, olive mill wastewaters, the edible mushroom Hericium erinaceus, Brewer’s spent grain, broccoli byproducts, cardoon, and Norway spruce bark. Moreover, the effect of different treatments such as blanching, microwave exposure, roasting, and enzymatic browning on the phytochemical content and bioactivity of the extracts is also addressed. Readers will find valuable insights into the impact of extraction methodologies on the bioactivity of the extracts, along with an understanding of the vast potential of natural extracts for the quality of food products. Readership Food and nutrition researchers, health professionals, nutritionists, and food science and chemistry students

Keywords

Research & information: general --- supercritical fluid extraction --- pressurized liquid extraction --- ultrasound-assisted extraction --- trans-resveratrol --- Norway spruce bark --- shelf life --- byproducts --- fresh pasta --- vegetable extracts --- antimicrobial activity --- wood waste --- phenolic profile --- planar chromatography --- DPPH-HPTLC assay --- Cynara cardunculus L. --- cardoon leaves --- by-products --- antioxidant activity --- ferulic acid --- brewer’s spent grain --- alkaline hydrolysis --- adsorption --- synthetic resin --- macroporous resin XAD-7HP --- olive mill wastewaters --- oxidative stability --- polyphenols --- sunflower oil --- enzymatic browning --- antioxidant compounds --- Hericium erinaceus --- mushroom metabolites --- polyphenol oxidase --- tyrosinase --- laccase --- natural inhibitor --- selenomethionine --- green coffee --- acrylamide --- Arabica --- Robusta --- Maillard reaction --- selenium uptake --- pretreatment --- ultrasound assisted extraction—UAE --- rapid solid-liquid dynamic extraction—RSLDE --- gas chromatography-mass spectrometry—GC-MS --- antioxidants --- C. sativa --- T. vulgaris --- C. sativum --- pomegranate seeds --- oil --- microwave pretreatment --- total phenolic content --- antioxidant capacity --- Hyoseris radiata --- Hyoseris taurina --- Hypochaeris laevigata --- Hypochaeris radicata --- phytochemicals --- obesity --- diabetes type 2 --- n/a --- brewer's spent grain --- ultrasound assisted extraction-UAE --- rapid solid-liquid dynamic extraction-RSLDE --- gas chromatography-mass spectrometry-GC-MS

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