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The biennial TNF-family conferences have been held over the past 20 years, from the time that TNF was cloned. These meetings have followed the enormous progress in this field. Much is now known about the members of the TNF ligand and receptor families, their signaling proteins, mechanisms of action and cellular functions. This volume is the proceedings of the 12th TNF International Conference, held in April 2009. This conference focuses on the physiological, pathophysiological, and medical significance of these important regulators. Sessions at the meeting specifically address their involvement in immunity, development, apoptosis, autoimmunity, cancer, and infection, the normal function and pathology of the neuronal system, as well as major unresolved questions about their mechanisms of action.

Cell death -- Congresses. --- Cytokines -- Congresses. --- Tumor necrosis factor -- Congresses. --- Tumor necrosis factors -- Congresses. --- Tumor necrosis factor --- Intercellular Signaling Peptides and Proteins --- Publication Formats --- Cell Physiological Processes --- Publication Characteristics --- Proteins --- Peptides --- Biological Factors --- Cell Physiological Phenomena --- Amino Acids, Peptides, and Proteins --- Chemicals and Drugs --- Phenomena and Processes --- Cell Death --- Tumor Necrosis Factors --- Cytokines --- Congresses --- Biology --- Health & Biological Sciences --- Microbiology & Immunology --- Cachectin --- Lymphotoxin --- TNF (Immunology) --- Medicine. --- Immunology. --- Microbiology. --- Biomedicine. --- Biomedicine general. --- Microbial biology --- Microorganisms --- Immunobiology --- Life sciences --- Serology --- Clinical sciences --- Medical profession --- Human biology --- Medical sciences --- Pathology --- Physicians --- Glycoproteins --- Growth factors --- Macrophages --- Health Workforce --- Biomedicine, general.