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Since the first heart transplantation was performed by Dr. Christiaan Barnard in South Africa in 1967, there has been steady progress in terms of recipient selection, donor selection and management, surgical technique, preoperative management, immunosuppression, mechanical circulatory support during waiting for heart transplantation, especially in the last two decades. This book presents recent information in the field of heart transplantation. It includes thirteen chapters that address such topics as novel immunosuppression therapy and the role of transplant pharmacists, donor management and intervention for primary graft failure, mechanical circulatory, diagnostic modalities for cardiac allograft vasculopathy, surgical techniques, pediatric heart transplantation, and gene therapy. We hope that readers will find this book a useful resource because of its summarization of relevant details and issues that will facilitate the acquisition of emerging new information in each area of heart transplantation
Heart --- Transplantation. --- Heart transplantation --- Heart transplants --- Transplants, Heart --- Surgery
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Heart --- Surgery. --- Transplantation. --- Surgery, Primitive --- Medicine --- Heart transplantation --- Heart transplants --- Transplants, Heart --- Surgery
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Heart --- Lungs --- Transplantation --- Cœur --- Poumons --- Greffe --- Transplantation. --- Heart transplants --- Transplants, Heart --- Lung --- Cardiopulmonary system --- Chest --- Respiratory organs --- Cardiovascular system --- Surgery
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This is a comprehensive translational reference covering a range of topics within heart transplantation. Including review of the procedure itself, preoperative requirements, potential complications and follow-up with the most up-to-date research and literature review, it introduces the embryology, anatomy, physiology, pathology and cardio-immunology of the heart. It also delves into other aspects of heart transplantation including organ procurement, religious aspects, the ethical issues that can emerge prior or during the surgery and discussion of the continued development of artificial hearts. The book explores multiorgan transplantation and their outcomes and complications. Heart Transplantation discusses the topic using illustrations and charts to aid understanding, allowing readers to gain a full understanding of the whole procedure easily. A list of practical surgical questions are presented at the end of each chapter to encourage the reader to challenge their understanding of the topic. With an emphasis on an interconnected approach to studying heart transplantation, this book presents a novel approach to educating surgeons in this challenging area of surgery. It is therefore an important addition to the literature for all involved in the management of heart transplantation from surgical residents to surgical nurses, cardiologists, anesthesiologists and experienced cardiac surgeons.
Heart --- Transplantation. --- Transplantation --- Complications. --- Heart transplantation --- Heart transplants --- Transplants, Heart --- Surgery --- Heart Transplantation. --- Cardiac Surgical Procedures . --- Trasplantament cardíac --- Complicacions quirúrgiques
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This handbook is an easy reference for those involved in the management of heart transplant. While this compilation of best practices cannot address the complexity of the individual patients we care for on a daily basis, it will serve to help us ask the right questions, access the best evidence and ultimately make the best decisions for the patients involved. Clinical Guide to Heart Transplantation provides a current review of the field of heart transplantation and how it has evolved into an established therapy for the treatment of end-stage heart failure. With the advent of improved surgical techniques, the development of immunosuppressive drugs and the utilization of more sophisticated monitoring strategies and treatments for graft rejection, heart transplantation now offer patients an avenue to both improved survival and quality of life. With over 4000 heart transplants performed per year globally and with 1-year survival approaching 90%, this practical title assists those involved in the this most complex of procedures to establish best practice. It is therefore essential reading for all practitioners in this field, charged with making critical decisions in the management of patients, donor organs, and the transplant process itself in order to achieve the greatest benefit in the utilization of this often scarce resource.
Medicine. --- Cardiology. --- Cardiac surgery. --- Medicine & Public Health. --- Cardiac Surgery. --- Heart --- Transplantation. --- Heart transplantation --- Heart transplants --- Transplants, Heart --- Surgery --- Surgery. --- Internal medicine --- Cardiac surgery --- Open-heart surgery --- Diseases
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This is the first book to focus entirely on the role of pathology in cardiac transplantation, linked to the clinical perspective through clinical–pathological correlation, multidisciplinary team working, and collaborative research. It provides a scientific framework with up-to-date pathological protocols and classification schemes and guides the reader through the chronological phases of the transplant process in a step-by-step approach. Topics include end-stage heart failure with pathologies encountered in the native heart, current issues surrounding donor selection, the multiple faces of rejection pathology correlated with clinical management and immunology, other post-transplant complications, details of pediatric and combined heart/other organ transplantation, and a useful practical appendix. Many high-quality images and illustrative cases are presented, along with learning points and ample references. Transplantation medicine today is continuously changing as collaborative research into novel diagnostic techniques and immunosuppressive therapies translates into improved recipient management and survival. This book is aimed at practicing transplant pathologists and specialist trainees. It will also appeal to general pathologists and to physicians and surgeons involved in cardiac transplantation who need to understand the role of pathology in the clinical management of transplant recipients.
Heart transplantation --- Heart transplants --- Transplants, Heart --- Heart --- Transplantation. --- Surgery --- Pathology. --- Cardiology. --- Immunology. --- Cardiac Surgery. --- Surgery. --- Immunobiology --- Life sciences --- Serology --- Cardiac surgery --- Open-heart surgery --- Internal medicine --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- Cardiac surgery.
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This work provides a one-of- a-kind volume that includes all aspects of heart transplantation from its historic beginning to its current day standards which now make the procedure a long-term treatment option for heart failure patients. The subjects covered include technical aspects of the procurement and implant procedures, as well as the medical nuances of pre-operative preparation and post-transplant immunosuppression management; the current day multi-disciplinary make up of the transplant team along with information on the keys to building and running a successful transplant program; regulatory standards and listing policies and the impact of the growing mechanical circulatory support technologies on the transplant field; and emerging technologies and future possibilities. All chapters are written by experts in the field and include the most up-to-date peer reviewed studies and clinical guidelines. This book gives an ever-changing reference that will become the text of choice for those beginning or continuing their transplant careers.
Surgical transplantation. --- Cardiology. --- Anesthesiology. --- Transplant Surgery. --- Anaesthesiology --- Surgery --- Heart --- Internal medicine --- Medical transplantation --- Organ transplantation --- Organ transplants --- Organs (Anatomy) --- Surgical transplantation --- Tissue transplantation --- Tissues --- Transplants, Organ --- Preservation of organs, tissues, etc. --- Procurement of organs, tissues, etc. --- Diseases --- Transplantation --- Transplant surgery --- Transplantation surgery --- Transplantation. --- Heart transplantation --- Heart transplants --- Transplants, Heart
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This book is a comprehensive overview of heart failure and cardiac transplantation and integrates scientific and clinical information about the physiology, pathophysiology, diagnosis, and treatment of this disorder. Organized into five parts, it reviews the history and basic mechanisms of heart failure; etiology of heart failure; heart failure disease progression; advanced therapies for heart failure; and cardiac transplantation. The book presents basic concepts in the physiology, molecular biology, pathology, and epidemiology of the normal and failing heart; known causes of heart failure, such as right heart failure, valvular cardiomyopathy, molecular mechanisms of sarcomeric cardiomyopathies, and neuromuscular cardiomyopathy; cardiorenal syndrome; neurohormonal activation; cardiac resynchronization, ventricular assist devices; regenerative mechanisms; orthotopic heart transplantation; early and late management of the post-transplant patient; heart transplantation and antibody-mediated rejections; heart-lung transplantation; and cardiac xenotransplantation. Featuring contributions from leaders in the fields of heart failure, cardiac transplantation, cardiac pathology, and cardiovascular molecular research, Congestive Heart Failure and Cardiac Transplantation is a valuable compendium for cardiologists, cardiothoracic surgeons, researchers, trainees, and students. .
Medicine. --- Cardiology. --- Cardiac surgery. --- Thoracic surgery. --- Surgical transplantation. --- Medicine & Public Health. --- Transplant Surgery. --- Thoracic Surgery. --- Cardiac Surgery. --- Congestive heart failure. --- Heart --- Transplantation. --- Heart transplantation --- Heart transplants --- Transplants, Heart --- Heart failure --- Surgery --- Transplantation of organs, tissu. --- Surgery. --- Cardiac surgery --- Open-heart surgery --- Thoracic surgery --- Thoracic surgeons --- Internal medicine --- Diseases --- Medical transplantation --- Organ transplantation --- Organ transplants --- Organs (Anatomy) --- Surgical transplantation --- Tissue transplantation --- Tissues --- Transplant surgery --- Transplantation surgery --- Transplants, Organ --- Preservation of organs, tissues, etc. --- Procurement of organs, tissues, etc. --- Transplantation
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