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Translational NeuroImmunology: Neuroinflammation updates on bench to bedside studies on neurological disorders that have immunological etiologies. The book covers neuroimmunology and the principles of autoimmune and autoinflammatory neurological disorders, with multiple sclerosis as the main focus. The immunopathology, genetics and epigenetics, microbiome, diagnosis and treatment of multiple sclerosis will be explained in ten chapters. A chapter also examines distinct aspects of pericytes, with final discussions on the neurologic manifestations, diagnostic approaches and treatments of the various neuroimmune disorders and lessons learned from translational research on non-human primates and zebrafish. All sections are presented in an accessible, practical format, making this volume a valuable resource for immunologists, neurologists and researchers in translational biomedical research.
Neuroimmunology. --- Inflammation. --- Neuroimmunomodulation --- Inflammation --- Translational Science, Biomedical
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"Translational Autoimmunity: Autoimmune Diseases in Different Clinical Settings addresses autoimmunity and associated conditions, such as aging, infectious diseases, cancer, neurodegeneration, psychological disorders, fertility, inflammatory vascular diseases, and interstitial lung diseases. The book addresses sufficiently basic questions on how the immune system is designed to distinguish self from no self and behave such that it's able to maintain self-tolerance, how does it work in infections, and how it elicits an auto-reactive state and develops self-antigens seen in autoimmune conditions. This is followed by an overview on the genetic and clinical aspects of the spectrum of autoimmune diseases which are broadly categorized into two types of organ specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases)."--
Autoimmunity --- Autoallergy --- Immunity --- Autoantibodies --- Autoimmunity. --- Autoimmune diseases. --- Immunology. --- Autoimmune Diseases --- Translational Science, Biomedical --- Clinical Medicine
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"Translational Autoimmunity: Treatment of Autoimmune Diseases, Volume Two in the Translational Immunology series, focuses on advances in therapeutic modalities in autoimmune diseases. Efficacy and safety of not only the current biologic therapies, but also novel drug targets are discussed. Therapeutic targeting of B regulatory cells, T regulatory cells, as well as the immunomodulation effects of nanoparticles and organisms are also covered, along with our understanding and future challenges of prognostic significance of treatments in autoimmune diseases."--
Autoimmune diseases --- Treatment. --- Autoimmunologic diseases --- Autoimmunity --- Immunologic diseases --- Autoimmunity. --- Immunology. --- Autoimmune Diseases --- Allergy and Immunology --- Translational Science, Biomedical --- therapy
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"Perioperative Neurosciences: Translational Research examines current clinical research focused on complications and the improvement of patient outcomes in neuroanesthesia and neurocritical care. The book addresses important translational topics including neuroanesthetics, pharmacogenomics, neuroprotection and neurotoxicity. In addition, it covers special considerations for topics such as stroke, traumatic brain injury and pain, as well as for specific patient populations like geriatric and pediatric."--
Nervous system --- Surgery. --- Nerves --- Neurosurgery --- Surgery --- Anesthesia in neurology. --- Neurological intensive care. --- Neurosciences --- Anesthesia --- Translational Science, Biomedical --- Perioperative Period --- Perioperative Medicine --- Complications. --- Research. --- methods
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"As the autoimmune diseases could affect different organs, Translational Autoimmunity: Autoimmune Diseases in Different Organs addresses the spectrum of autoimmune diseases. The fourth volume of Translational Immunology Series focuses on clinical and laboratory details of autoimmune diseases which are broadly categorized into two types of organ-specific autoimmune diseases and non-organ specific autoimmune diseases (also known as systemic autoimmune diseases). Autoimmune rheumatic diseases such as systemic lupus erythematosus and rheumatoid arthritis, autoimmune rheumatic diseases such as diabetes mellitus and thyroid diseases, autoimmune neurologic diseases such as multiple sclerosis, as well as autoimmune hepatobiliary diseases, autoimmune renal diseases and autoimmune cutaneous diseases as the subject of discussion in Translational Autoimmunity: Autoimmune Diseases in Different Organs."--
Autoimmunity. --- Immunology. --- Immunobiology --- Life sciences --- Serology --- Autoallergy --- Immunity --- Autoantibodies --- Immunology --- Research. --- Technique. --- Autoimmune Diseases. --- Autoimmunity --- Autoimmune Diseases --- Translational Science, Biomedical --- Clinical Medicine
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Translational Surgery covers the principles of evidence-based medicine and applies these principles to the design of translational investigations. The reader will come to fully understand important concepts including case-control studies, prospective cohort studies, randomized trials, and reliability studies. Investigators will benefit from greater confidence in their ability to initiate and execute their own investigations, avoid common pitfalls in surgical research, and know what is needed for collaboration. Further, this title is an indispensable tool in grant writing and funding efforts. The practical, straightforward approach helps the translational research navigate challenging considerations in study design and implementation. The book provides valuable discussions of the critical appraisal of published studies in surgery, allowing the reader to learn how to evaluate the quality of such studies. Thus, they will improve at measuring outcomes; making effective use of all types of evidence in patient care. In short, this practical guidebook will be of interest to every surgeon or surgical researcher who has ever had a good clinical idea, but not the knowledge of how to test it. Focuses on translational research in Surgery, covering the principles of evidence-based medicine and applying those principles to the design of translational investigations Provides a practical, straightforward approach to help surgeons and researchers navigate challenging aspects of study design and implementation Details valuable discussions on the critical appraisal of published studies in Surgery, allowing the reader to effectively use all types of evidence for patient care.
Surgery, Experimental. --- Experimental surgery --- Vivisection --- Surgery, Operative. --- Evidence-based medicine. --- Medicine --- Translational Science, Biomedical --- Evidence-Based Medicine --- Surgical Procedures, Operative --- Research.
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Biotechnology industry. --- Biotechnology --- Clinical medicine --- Drug development. --- Drugs --- Pharmaceutical industry. --- Biomarkers. --- Biomedical Research. --- Clinical Trials as Topic. --- Drug Development --- Pharmacology, Clinical. --- Risk Assessment. --- Translational Science, Biomedical. --- Risk assessment. --- Research. --- organization & administration.
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Bones --- Mineral metabolism --- Metabolism --- Metabolic Diseases --- Translational Science, Biomedical --- Os --- Métabolisme minéral --- Troubles du métabolisme minéral --- Métabolisme. --- Troubles du métabolisme. --- metabolism (biological concept) --- Disorders --- Diseases --- Disorders. --- Métabolisme --- Troubles du métabolisme --- Maladies
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The definitive work in D&I research — now completely updated and expandedDissemination and Implementation Research in Health is a practical guide to making research more consequential, a collection assembled and written by today's leading D&I researchers
Translational Science, Biomedical --- Information Dissemination --- Implementation Science. --- Recherche médicale translationnelle --- Diffusion de l'information --- Science de la mise en oeuvre. --- Médecine --- Diffusion sélective de l'information. --- methods. --- methods. --- méthodes. --- méthodes. --- Recherche.
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