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Aortic valve replacement with a bioprosthesis is an effective surgery for an elderly population suffering from stenosis or aortic valvular insufficiency and whose surgical indication should be stated as soon as symptoms appear in the presence of severe valvular stenosis. We conducted a quality control of surgical performance in the Mont-Godinne University Hospital Center by retrospectively studying a consecutive cohort of 617 patients who underwent aortic valve replacement surgery with a bioprosthesis between 1997 and 2007. Our intra-hospital mortality (9%) is between the values predicted by the Logistic Euroscore (11, 85%) based on a 1995 population) and those predicted by the 2010 Euroscore (6,54 % base on a 2010 population) and by the STS-score (4,84% based on a 2015 population). We found fewer intra-hospital complications than expected with 9% prolonged ventilations observed versus 17% expected and 5 % early reoperations observed versus 10% expected. Only sternal wound infections were more frequent than expected (1,4 % vs 0,33%). Euroscore 2010 and STS-score were the two highest performing scores in the prediction of mortality risk. The scores were average in terms of sensitivity and specificity and had a very low positive predictive value, but had an excellent negative predictive value approaching 97 %. They were therefore particularly effective in confirming a low surgical risk.Finally, our results showed that long-term survival was significantly associated with certain isolated parameters (age, associated CABG, history of cardiac surgery) and with risk scores. This effect was mainly present in the early postoperative phase. The results of our medical-surgical team are satisfactory, whether we compare intra-hospital mortality and complications with early mortality and were particularly good in terms of negative predictive values. They had an impact on long-term survival, with an essentially marked effect in early postoperative period. Le remplacement valvulaire aortique par bioprothèse est une chirurgie efficace pour une population âgée souffrant de sténose ou d’insuffisance valvulaire aortique, et dont l’indication opératoire devrait être posée dès l’apparition de symptômes en présence d’un rétrécissement valvulaire sévère. Nous avons effectué un contrôle de qualité de la performance chirurgicale au sein du CHU Mont-Godinne en étudiant de façon rétrospective une cohorte consécutive de 617 patients ayant bénéficié entre 1997 et 2007 d’une chirurgie de remplacement valvulaire aortique par bioprothèse. Notre mortalité intra-hospitalière (9%) se situe entre les valeurs prédites par l’Euroscores logistique (11,85 %, basé sur une population de 1995) et celles prédites par l’Euroscore 2010 (6,54% basé sur une population de 2010) et par le STS-score (4,84 % basé sur une population de 2015). Nous avons rencontré moins de complications intra-hospitalières qu’attendues avec 9 % de ventilations prolongées observées contre 17% attendues et 5 % de réopérations précoces observées contre 10 % attendues. Seules les infections de plaie sternale étaient plus fréquentes qu’attendues (1,4% vs 0,33%). L’Euroscore 2010 et le STS-Score furent les deux scores les plus performants dans la prédiction du risque de mortalité. Les scores se sont montrés moyens en termes de sensibilité et de spécificité et avaient une valeur prédictive positive très faible, mais possédaient en revanche une excellente valeur prédictive négative approchant les 97%. Ils furent donc particulièrement performants pour confirme un faible risque opératoire. Enfin, nos résultats ont mis en évidence que la survie à long terme était associée de façon significative à certains paramètres isolés (âge, PAC associé, antécédents de chirurgie cardiaque) et aux scores de risques. Cet effet était essentiellement présent durant la phase post-opératoire précoce. Les résultats de notre équipe médico-chirurgicale sont satisfaisants, que l’on compare la mortalité et les complications intra-hospitalières avec celles attendues ou avec la littérature. Les scores de risques étaient associés de façon significative à la mortalité précoce et se sont montrés particulièrement bons en termes de valeurs prédictives négatives. Ils ont montré un impact sur la survie à long terme, avec un effet essentiellement marqué en post-opératoire précoce.

Tissue and Organ Harvesting --- Tissue and Organ Procurement

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This book addresses ethical conflicts arising from saving the lives of patients who need a transplant while treating living and dead donors, organ sellers, animals, and embryos with proper moral regard. Our challenge is to develop a better world in the light of debatable values and uncertain consequences.

Tissue and Organ Procurement --- Tissue Donors --- Tissue and Organ Harvesting --- orgaandonatie (orgaanwegneming) --- Procurement of organs, tissues, etc. --- Transplantation of organs, tissues, etc. --- Organ procurement (Surgery) --- Tissue procurement (Surgery) --- Tissue banks --- ethics. --- don d'organes (prélèvement d'organes --- Moral and ethical aspects. --- Moral and religious aspects --- Tissue and Organ Harvesting -- ethics. --- Tissue and Organ Procurement -- ethics. --- Tissue Donors -- ethics. --- Surgical Procedures, Operative --- Persons --- Specimen Handling --- Health Services --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Named Groups --- Laboratory Techniques and Procedures --- Health Care Facilities, Manpower, and Services --- Diagnosis --- Health Care --- Procurement of organs, tissues, etc --- Transplantation of organs, tissues, etc --- ethics --- Moral and ethical aspects

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Donation of organs, tissues, etc. --- Procurement of organs, tissues, etc. --- Transplantation of organs, tissues, etc. --- Tissue and Organ Procurement --- Tissue and Organ Harvesting --- Undertakers and undertaking --- Bioprospecting --- Cadaver. --- Tissue banks --- Moral and ethical aspects. --- Moral and ethical aspects. --- Moral and ethical aspects. --- legislation & jurisprudence. --- ethics. --- ethics. --- ethics. --- ethics. --- United States. --- Great Britain.

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Cryopreservation of organs, tissues, etc --- Freezing --- Organ Preservation --- Congresses --- Cryopreservation of organs, tissues, etc. --- Freezing. --- Organ Preservation. --- Organ Preservations --- Preservation, Organ --- Preservations, Organ --- Tissue and Organ Harvesting --- Melting --- Cryoconservation of organs, tissues, etc. --- Cryogenic preservation of organs, tissues, etc. --- Low temperature preservation of organs, tissues, etc. --- Preservation of organs, tissues, etc. --- Cryobiology --- Cryonics --- Man --- Organs --- Preservation --- Conferences - Meetings --- -Cryoconservation of organs, tissues, etc. --- Congresses. --- -Congresses --- Cryopreservation of organs, tissues, etc - Congresses --- Freezing - congresses --- Organ Preservation - congresses

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This atlas provides transplant professionals with a step-wise approach to organ transplantation, illustrating the technical steps and highlighting practice points for each procedure. All aspects of abdominal and thoracic transplantation are covered with separate chapters addressing specific technical issues for heart and lung, liver, kidney, pancreas and intestinal transplantation, providing detailed approaches to difficult situations. Transplant surgeons, trainees, fellows and other professionals involved in transplantation will find this book to be an ideal reference point. It will help readers to: · Understand the process of transplantation · Become familiar with standard transplant techniques, whatever their discipline · Understand the technical variations and learn effective ways of approaching them · Learn ways to avoid mistakes and tips for safe and efficient surgery The book has been written by an experienced international team of authors with extensive knowledge in the field of transplantation. Many of the techniques described have been pioneered by the authors writing the relevant chapters.

Transplantation of organs, tissues, etc. --- Transplantation of organs, tissu. --- Nephrology. --- Heart --- Thoracic surgery. --- Surgical oncology. --- Transplant Surgery. --- Cardiac Surgery. --- Thoracic Surgery. --- Surgical Oncology. --- Surgery. --- Cancer --- Oncologic surgery --- Oncological surgery --- Surgical oncology --- Thoracic surgery --- Thoracic surgeons --- Cardiac surgery --- Open-heart surgery --- Internal medicine --- Kidneys --- Excision --- Treatment --- Diseases --- Surgery --- Surgical transplantation. --- Cardiac surgery. --- Medical transplantation --- Organ transplantation --- Organ transplants --- Organs (Anatomy) --- Surgical transplantation --- Tissue transplantation --- Tissues --- Transplant surgery --- Transplantation surgery --- Transplants, Organ --- Preservation of organs, tissues, etc. --- Procurement of organs, tissues, etc. --- Transplantation --- Organ Transplantation --- Tissue and Organ Harvesting --- methods.