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It has become increasingly evident in recent years that, apart from the key role that thrombin plays in the blood coagulation cascade, thrombin also elicits cellular actions via the activation of proteinase-activated receptors, which are present in many cell types. These effects of thrombin are seen in a variety of physiological as well as pathological phenomena, including vascular development and physiology, tumor progression and metastasis, neuronal functions, inflammation, angiogenesis. Thrombin: Physiology and Disease, edited by Michael E. Maragoudakis and Nikos E. Tsopanoglou, emphasizes the new developments in this important field of research and provides the basis for translating these findings into therapeutic targets.".

Optical communications. --- Semiconductors. --- Thrombin --- Blood --- Thrombolytic therapy --- Receptors, G-Protein-Coupled --- Platelet Membrane Glycoproteins --- Receptors, Peptide --- Serine Endopeptidases --- Receptors, Proteinase-Activated --- Blood Coagulation Factors --- Biological Science Disciplines --- Receptors, Cell Surface --- Serine Proteases --- Membrane Glycoproteins --- Blood Proteins --- Endopeptidases --- Biological Factors --- Natural Science Disciplines --- Receptors, Thrombin --- Physiology --- Peptide Hydrolases --- Membrane Proteins --- Chemicals and Drugs --- Disciplines and Occupations --- Proteins --- Glycoproteins --- Hydrolases --- Amino Acids, Peptides, and Proteins --- Enzymes --- Enzymes and Coenzymes --- Human Anatomy & Physiology --- Electrical & Computer Engineering --- Medicine --- Health & Biological Sciences --- Engineering & Applied Sciences --- Oncology --- Telecommunications --- Physiological effect --- Coagulation --- Thrombin. --- Thrombolytic therapy. --- Physiological effect. --- Coagulation. --- Fibrinolytic therapy --- Thrombolysis --- Thrombosis --- Blood coagulation --- Clotting of blood --- Coagulation of blood --- Fibrinogenase --- Thrombase --- Thrombosin --- Chemotherapy --- Clotting --- Large scale systems --- Systèmes de grandes dimensions --- Systèmes de grandes dimensions --- Halvledarkomponenter --- Halvledarkomponenter. --- Medicine. --- Cancer research. --- Human physiology. --- Pharmacology. --- Epidemiology. --- Biochemistry. --- Biomedicine. --- Human Physiology. --- Cancer Research. --- Pharmacology/Toxicology. --- Biochemistry, general. --- Fibrinolysis --- Hemostasis --- Anticoagulants (Medicine) --- Coagulase --- Blood coagulation factors --- Hemostatics --- Serine proteinases --- Economics --- Computer engineering --- Mathematical models --- System theory --- Economie politique --- Congresses --- Modèles mathématiques --- Congrès --- Oncology. --- Toxicology. --- Diseases --- Public health --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Biology --- Chemistry --- Medical sciences --- Chemicals --- Pharmacology --- Poisoning --- Poisons --- Tumors --- Human biology --- Human body --- Composition --- Toxicology --- Drug effects --- Medical pharmacology --- Drugs --- Pharmacy --- Cancer research --- Economics - Mathematical models - Congresses --- Large scale systems - Congresses