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There have been tremendous strides in cellular transplantation in recent years, leading to accepted practice for the treatment of certain diseases, and use for many others in trial phases. The long history of cellular transplantation, or the transfer of cells from one organism or region of the body to another, has been revolutionized by advances in stem cell research, as well as developments in gene therapy. Cellular Transplants: From Lab to Clinic provides a thorough foundation of the basic science underpinning this exciting field, expert overviews of the state-of-the-art, and
Cellular therapy. --- Cell therapy --- Cells --- Therapy, Cellular --- Organotherapy --- Therapeutics, Physiological --- Transplantation of organs, tissues, etc. --- Cell transplantation --- Therapeutic use
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Cell Transplantation --- Cytokines --- Cellular therapy --- Therapeutic use --- Transplantation, Cell --- Cells --- Cellular transplantation --- Cell therapy --- Therapy, Cellular --- transplantation --- Transplantation --- Transplantation of organs, tissues, etc. --- Cellular immunity --- Immune response --- Organotherapy --- Therapeutics, Physiological --- Cell transplantation --- Regulation --- Cell Transplantation.
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Cellular Therapy and Transplantation is a new international, peer-reviewed, open access journal which publishes articles in the fields of cellular and genetic therapy and transplantation. While the journal is international in scope and publication, one of its aims is to provide a forum for work undertaken by scientists from the former Soviet Union and make it widely accessible.
Cellular therapy --- Cell transplantation --- Oncology --- Cell Transplantation. --- Cell transplantation. --- Cellular therapy. --- Oncology. --- Transplantation, Cell --- Cells --- Cellular transplantation --- Cell therapy --- Therapy, Cellular --- transplantation --- Transplantation --- Therapeutic use --- Transplantation of organs, tissues, etc. --- Organotherapy --- Therapeutics, Physiological --- Tumors --- Cell Transplantation
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As our world continues to evolve, the field of regenerative medicine f- lows suit. Although many modern day therapies focus on synthetic and na- ral medicinal treatments for brain repair, many of these treatments and prescriptions lack adequate results or only have the ability to slow the p- gression of neurological disease or injury. Cell therapy, however, remains the most compelling treatment for neurodegenerative diseases, disorders, and injuries, including Parkinson’s disease, Huntington’s disease, traumatic brain injury, and stroke, which is expanded upon in more detail in Chapter 1 by Snyder and colleagues. Cell therapy is also unique in that it is the only therapeutic strategy that strives to replace lost, damaged, or dysfunctional cells with healthy ones. This repair and replacement may be due to an administration of exogenous cells itself or the activation of the body’s own endogenous reparative cells by a trophic, immune, or inflammatory response to cell transplantation. However, the precise mechanism of how cell therapy works remains elusive and is c- tinuing to be investigated in terms of molecular and cellular responses, in particular. Moreover, Chapter 11 by Emerich and associates, discusses some of the possibilities of cell immunoisolation and the potential for treating central nervous system diseases.
Brain --- Cellular therapy. --- Cell therapy --- Cells --- Therapy, Cellular --- Cerebrum --- Mind --- Diseases --- Treatment. --- Therapeutic use --- Medicine. --- Neurosciences. --- Biomedicine. --- Organotherapy --- Therapeutics, Physiological --- Transplantation of organs, tissues, etc. --- Cell transplantation --- Central nervous system --- Head
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Developing Costimulatory Molecules for Immunotherapy of Diseases highlights the novel concept of reverse costimulation and how it can be effectively exploited to develop immunotherapy using either humanized antibodies against CD80, CD86, and other costimulatory molecules or CD28 fusinogenic proteins in the treatment of diseases, including allergies, asthma, rheumatoid arthritis, multiple sclerosis, lupus nephritis, severe psoriasis, vulgaris tuberculosis, thopoid, transplantation therapeutic, cancer, and inflammation. The text aims to provide the latest information on the complex roles an
Immunologic diseases --- Cellular therapy. --- Immunotherapy. --- Treatment. --- Therapeutic immunology --- Clinical immunology --- Therapeutics --- Cell therapy --- Cells --- Therapy, Cellular --- Organotherapy --- Therapeutics, Physiological --- Transplantation of organs, tissues, etc. --- Cell transplantation --- Immune diseases --- Immune disorders --- Immune system --- Immunologic disorders --- Immunological diseases --- Diseases --- Therapeutic use
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Guide to Cell Therapy GxP: Quality Standards in the Development of Cell-Based Medicines in Non-Pharmaceutical Environments provides a practical guide to the implementation of quality assurance systems for successful performance of all cell-based clinical trials. The book includes all information that should be used in investigational medicinal product dossier (IMPD), the launching point for any clinical investigation, and beyond, bridging the gap in knowledge with the inclusion of examples of design of GLP-compliant preclinical studies, design of bioprocesses for autologous/allogeneic thera
Human medicine --- Cellular therapy. --- Blood --- Transfusion, Autologous --- Treatment. --- Body fluids --- Fear of blood --- Cell therapy --- Cells --- Therapy, Cellular --- Organotherapy --- Therapeutics, Physiological --- Transplantation of organs, tissues, etc. --- Cell transplantation --- Therapeutic use
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Cell therapy --- Cell transplantation --- Cells--Therapeutic use --- Cells--Transplantation --- Cellulaire therapie --- Cellulaire transplantatie --- Cellular therapy --- Cellular transplantation --- Cellules--Transplantation --- Celtherapie --- Celtransplantatie --- Therapie [Cellulaire ] --- Therapy [Cellular ] --- Thérapie cellulaire --- Transplantatie [Cel] --- Transplantation cellulaire --- Cloning --- Fetus --- Clonage --- Foetus --- Research --- Therapeutic use --- Recherche --- Emploi en thérapeutique --- therapeutisch kloneren (therapeutisch klonen) --- clonage thérapeutique (clonage humain thérapeutique) --- Thérapie cellulaire --- Emploi en thérapeutique --- Cellules souches embryonnaires --- Transplantation --- Clone cells
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This book familiarizes the reader with the current landscape of cell-based therapies for the treatment of retinal disease, including diseases that affect the choriocapillaris, retinal pigment epithelium, photoreceptors, and retinal ganglion cells. Instead of utilizing a disease-centric approach to the topic, this book—edited by world-renowned stem cell scientists—focuses on strategies for developing and transplanting the cells. This includes the creation of replacement cells, cell-based neuroprotection, and in vitro disease modeling and testing. The final chapters briefly review parallel approaches that do not directly utilize cellular transplantation. The use of cellular transplantation to treat retinal disease has recently become a viable and exciting therapeutic approach. The visibility of the retina and its laminar cellular architecture render it an ideal organ for the development of surgically delivered cellular therapies. Having an in-depth understanding of the current state of cell therapy for the eye is an essential first step toward utilizing similar approaches in other organs. Ophthalmologists, translational clinician-scientists, stem cell scientists, and researchers interested in eye disease will find Cellular Therapies for Retinal Disease: A Strategic Approach essential reading and it is also suitable for workshops or courses at the undergraduate or Ph.D. level.
Life sciences. --- Ophthalmology. --- Stem cells. --- Life Sciences. --- Stem Cells. --- Retina --- Cellular therapy. --- Diseases. --- Diseases --- Treatment. --- Cell therapy --- Cells --- Therapy, Cellular --- Therapeutic use --- Organotherapy --- Therapeutics, Physiological --- Transplantation of organs, tissues, etc. --- Cell transplantation --- Posterior segment (Eye) --- Colony-forming units (Cells) --- Mother cells --- Progenitor cells --- Medicine --- Eye
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This volume provides a comprehensive, state-of-the art review of the field of cell therapy. The volume begins with an overview of the breadth of the field and then turns to overviews of imaging technologies that can aid in both safety and efficacy evaluations. The book then turns to numerous contributions detailing the rapidly growing field of stem cell therapies. These sections cover our understanding of the natural roles of stem cells in biology and human disease and then touches on several of the more prominent areas where stem cells are moving rapidly into clinical evaluation including neurodegenerative diseases, muscular dystrophy, cardiac repair, and diabetes. The volume concludes with contributions from experts in oncology, ophthalmiology, stem cells, 3-D printing, and biomaterials where the convergence of expertise is leading to unprecedented insights into how to minutely control the in vivo fate and function of transplanted and/or endogeneously mobilized cells. Finally, the book provides insights into the pivotal relationship between academic and industrial partnerships. This volume is designed to touch on the major areas where the field will make its greatest and most immediate clinical impacts. This text will provide a useful resource for physicians and researchers interested in the rapidly changing filed of cell therapy.
Medicine. --- Radiology. --- Oncology. --- Pathology. --- Cell biology. --- Medicine & Public Health. --- Diagnostic Radiology. --- Cell Biology. --- Cellular therapy. --- Cell therapy --- Cells --- Therapy, Cellular --- Organotherapy --- Therapeutics, Physiological --- Transplantation of organs, tissues, etc. --- Cell transplantation --- Therapeutic use --- Radiology, Medical. --- Oncology . --- Cytology. --- Cell biology --- Cellular biology --- Biology --- Cytologists --- Tumors --- Clinical radiology --- Radiology, Medical --- Radiology (Medicine) --- Medical physics --- Disease (Pathology) --- Medical sciences --- Diseases --- Medicine --- Medicine, Preventive --- Radiological physics --- Physics --- Radiation
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Human genetics --- Cellular therapy --- Gene therapy --- Cancer --- Therapy, Gene --- Genetic engineering --- Therapeutics --- Cell therapy --- Cells --- Therapy, Cellular --- Organotherapy --- Therapeutics, Physiological --- Transplantation of organs, tissues, etc. --- Cell transplantation --- Therapeutic use --- Cancer. --- Cellular therapy. --- Gene therapy. --- Cancers --- Carcinoma --- Malignancy (Cancer) --- Malignant tumors --- Tumors
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