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This monograph presents the geoscientific context arising in decorrelative gravitational exploration to determine the mass density distribution inside the Earth. First, an insight into the current state of research is given by reducing gravimetry to mathematically accessible, and thus calculable, decorrelated models. In this way, the various unresolved questions and problems of gravimetry are made available to a broad scientific audience and the exploration industry. New theoretical developments will be given, and innovative ways of modeling geologic layers and faults by mollifier regularization techniques are shown. This book is dedicated to surface as well as volume geology with potential data primarily of terrestrial origin. For deep geology, the geomathematical decorrelation methods are to be designed in such a way that depth information (e.g., in boreholes) may be canonically entered. Bridging several different geo-disciplines, this book leads in a cycle from the potential measurements made by geoengineers, to the cleansing of data by geophysicists and geoengineers, to the subsequent theory and model formation, computer-based implementation, and numerical calculation and simulations made by geomathematicians, to interpretation by geologists, and, if necessary, back. It therefore spans the spectrum from geoengineering, especially geodesy, via geophysics to geomathematics and geology, and back. Using the German Saarland area for methodological tests, important new fields of application are opened, particularly for regions with mining-related cavities or dense development in today's geo-exploration. .

Potential theory (Mathematics). --- Numerical analysis. --- Physical geography. --- Gravitation. --- Potential Theory. --- Numerical Analysis. --- Earth System Sciences. --- Classical and Quantum Gravitation, Relativity Theory. --- Geography --- Field theory (Physics) --- Matter --- Physics --- Antigravity --- Centrifugal force --- Relativity (Physics) --- Mathematical analysis --- Green's operators --- Green's theorem --- Potential functions (Mathematics) --- Potential, Theory of --- Mechanics --- Properties --- Potential theory (Mathematics) --- Teoria del potencial (Matemàtica) --- Fórmula de Green --- Funcions potencials --- Operadors de Green --- Teorema de Green --- Teoria del potencial --- Anàlisi matemàtica --- Mecànica --- Efecte túnel --- Teoria del potencial (Física) --- Varietats de Riemann

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Despite intense investigation of plant embryogenesis, there are still various open questions in this fascinating field. For example, our knowledge is still poor in relation to the spatiotemporal dynamics and the regulatory mechanisms of various embryonic events at all levels of whole plants, organs, tissues, cells, and molecules. We also need to understand the generality and diversity of embryonic features in a diverse range of species and also the bioengineering technologies to improve reproductive traits. Therefore, in this Special Issue, we show various articles, including original research papers and reviews, to expand our knowledge on plant embryogenesis, including works spanning from the various novel protocols of model plants to the regulations of somatic embryogenesis in agricultural plants.

tobacco --- embryogenesis --- suspensor --- programmed cell death --- TUNEL --- low-fluence --- red light --- shoot regeneration --- WUS --- NPA --- antioxidative enzymes --- arabinogalactan proteins --- centaury --- Gentianaceae --- in vitro culture --- morphogenesis --- plant growth regulators --- somatic embryo --- tissue culture --- clearing --- 3D imaging --- Arabidopsis thaliana --- embryo --- confocal microscopy --- cell wall staining --- fluorescent reporter --- GFP --- cyclic somatic embryogenesis --- direct somatic embryogenesis --- indirect somatic embryogenesis --- leaf explant --- histology --- 2,4-D --- CPPU --- auxins --- cytokinins --- regeneration --- picloram --- cryoplate --- vitrification solutions --- long-term preservation --- fertilization --- male excess --- parental genome --- paternal genome --- polyspermy --- rice --- epidermal development --- ATML1 --- transcriptional regulation --- post-transcriptional regulation

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Mitochondria are subcellular organelles evolved by the endosymbiosis of bacteria with eukaryotic cells. They are the main source of ATP in the cell and engaged in other aspects of cell metabolism and cell function, including the regulation of ion homeostasis, cell growth, redox status, and cell signaling. Due to their central role in cell life and death, mitochondria are also involved in the pathogenesis and progression of human diseases/conditions, including neurodegenerative and cardiovascular disorders, cancer, diabetes, inflammation, and aging. However, despite the increasing number of studies, precise mechanisms whereby mitochondria are involved in the regulation of basic physiological functions, as well as their role in the cell under pathophysiological conditions, remain unknown. A lack of in-depth knowledge of the regulatory mechanisms of mitochondrial metabolism and function, as well as interplay between the factors that transform the organelle from its role in pro-survival to pro-death, have hindered the development of new mitochondria-targeted pharmacological and conditional approaches for the treatment of human diseases. This book highlights the latest achievements in elucidating the role of mitochondria under physiological conditions, in various cell/animal models of human diseases, and in patients.

hypoglycemia --- sodium dichloroacetate --- pyruvate dehydrogenase kinase --- pyruvate dehydrogenase --- oxidative stress --- neuron death --- cholangiocellular carcinoma --- mitochondria --- energy metabolism --- oxidative phosphorylation --- 4-HNE --- DRP1 --- ERK1/2 --- hippocampus --- JNK --- mitochondrial dynamics --- PKA --- protein phosphatases --- TUNEL --- DDE --- high-fat diet --- mitochondrial UCP2 --- ROS --- antioxidant system --- uncoupling protein --- mitochondria: energy metabolism --- lipid handling --- fatty acid oxidation --- potassium channel --- reactive oxygen species --- antioxidants --- life span --- aging --- BKCa channels --- pravastatin --- gemfibrozil --- liver --- colon --- mitochondrial function --- cyclosporin A --- mitochondria calcium buffering --- mitochondria bioenergetics --- mitochondria permeability transition pore --- inorganic phosphate --- hepatic fibrogenesis --- HtrA2/Omi --- reactive oxygen species stress --- mitochondrial homeostasis --- complex I (CI) deficiency --- metabolome and proteome profiling --- reactive oxygen species (ROS) --- respirasome assembly --- electron tunneling (ET) --- perilipin 5 --- lipid droplet --- H9c2 cardiomyoblasts --- adenine nucleotide translocase --- respiratory supercomplexes --- ETC complexes --- dentate granule cell --- epilepsy --- hyperforin --- LONP1 --- neuroprotection --- pilocarpine --- seizure --- siRNA --- cardioprotection --- mitochondrial permeability transition pores --- mitochondrial connexin 43 --- cardiolipin --- iron overload --- hepcidin --- transferrin --- ferritin --- ZIP --- inflammation --- mtDNA --- mitochondrial dysfunction --- muscle aging --- physical performance --- LHON --- Siberian population --- ancient mutation --- specific genetic background --- apoptosis --- human amniotic membrane --- mitochondrial cell death --- BAX --- BCL-2 --- tensile strength --- mitochondrial gene expression --- mtDNA transcription --- mtRNA --- post-transcriptional mtRNA processing --- dsRNA --- innate immunity --- interferon response --- amino acid neurotransmitter --- cerebellar amino acid metabolism --- hypoxia --- 2-oxoglutarate dehydrogenase --- tricarboxylic acid cycle --- heart --- cytoskeletal proteins --- mitochondrial interactions --- plectin --- tubulin beta --- signaling --- GW9662 --- ischemia reperfusion injury --- Langendorff --- myocardial --- pioglitazone --- redox state --- rosiglitazone --- TZD --- uncoupling --- ADP/ATP carrier --- KmADP --- dextran --- morphology --- cardiomyocytes --- telomere length --- telomerase activity --- development --- regeneration --- intranuclear mitochondria --- healthy cells --- electron and confocal microscopy --- signaling pathways --- ion homeostasis --- human diseases