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Immune response --- T cells --- RECEPTORS --- T-Lymphocytes --- Regulation --- Congresses. --- ANTIGEN, T-CELL, immunology --- immunology --- physiology --- Immunology --- Physiology --- Receptors --- T-lymphocytes --- Antigen, t-cell, immunology --- Congresses --- T cells - Congresses. --- Immune response - Regulation - Congresses.

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Pharmaceutical companies are spending increasing amounts of money on drug discovery and development. Nevertheless, attrition rates in clinical development are still very high, and up to 90% of new compounds fail in clinical phase I - III trials, which is partially due to lack of clinical efficacy. This indicates a strong need for highly predictive in vitro and in vivo models. The "50th International Workshop of the Ernst Schering Research Foundation" focussed on "Animal Models of T Cell-Mediated Skin Diseases". Such animal models should have impact not only on inflammatory dermatoses but also on other inflammatory disorders due to their model character. The current volume summarises recent advances in animal research that are important for anti-inflammatory drug discovery.

Immunologic diseases -- Animal models -- Congresses. --- Skin -- Inflammation -- Animal models -- Congresses. --- T cells -- Congresses. --- Skin --- T cells --- Immunologic diseases --- Models, Animal --- Skin and Connective Tissue Diseases --- Models, Biological --- Animal Diseases --- Disease Models, Animal --- Skin Diseases --- Investigative Techniques --- Models, Theoretical --- Diseases --- Analytical, Diagnostic and Therapeutic Techniques and Equipment --- Medicine --- Dermatology --- Health & Biological Sciences --- Animal models --- Inflammation --- T lymphocytes --- Thymus-dependent cells --- Thymus-dependent lymphocytes --- Thymus-derived cells --- Cutis --- Integument (Skin) --- Chemistry. --- Medicinal chemistry. --- Dermatology. --- Internal medicine. --- Respiratory organs --- Cell biology. --- Medicinal Chemistry. --- Biomedicine general. --- Cell Biology. --- Pneumology/Respiratory System. --- Internal Medicine. --- Diseases. --- Lymphocytes --- Beauty, Personal --- Body covering (Anatomy) --- Biochemistry. --- Medicine. --- Cytology. --- Pneumology. --- Medicine, Internal --- Cell biology --- Cellular biology --- Biology --- Cells --- Cytologists --- Clinical sciences --- Medical profession --- Human biology --- Life sciences --- Medical sciences --- Pathology --- Physicians --- Biological chemistry --- Chemical composition of organisms --- Organisms --- Physiological chemistry --- Chemistry --- Composition --- Biomedicine, general. --- Respiratory organs—Diseases. --- Health Workforce --- Chemistry, Medical and pharmaceutical --- Chemistry, Pharmaceutical --- Drug chemistry --- Drugs --- Medical chemistry --- Medicinal chemistry --- Pharmacochemistry --- Respiratory diseases --- Biomedical Research. --- Research. --- Biological research --- Biomedical research --- Mice --- As laboratory animals