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With the advances in nanomaterials and nanofabrication, surface-enhanced Raman spectroscopy (SERS) has been extensively developed and applied in the trace detection of various analytes in either a simple or a complicated sample matrix. This includes, but is not limited to, the detection of antibiotic residues in animal-producing meat products, detection of pathogenic bacteria in human body fluid, and detection of heavy metal contamination of water. This book, consisting two review articles and five research articles, covers the most recent progress and advancement in the development and application of various nanomaterials in SERS trace detection. In this book, a broad range of topics is covered, from the synthesis of novel nanomaterials that can provide improved reproducibility of SERS signals to the development of new application protocols that can facilitate the reliable detection of trace amounts of analytes without interfered by the sample matrices significantly. This book is a useful source for both new and advanced researchers in the field of SERS and its application.

Technology: general issues --- SERS --- Ag NPs --- coffee ring --- pesticide detection --- Surface-enhanced Raman spectroscopy (SERS) --- wire mesh --- steel mesh --- SERS platform --- Escherichia coli --- Bacillus subtilis --- biomolecule --- surface enhanced Raman spectroscopy (SERS) --- nanomaterial --- analysis --- identification --- biology --- chemometrics --- resistance --- biosensing --- rapid detection --- Ag nanowires --- tartrazine --- large yellow croaker --- surface-enhanced Raman spectroscopy --- transformer aging --- concentration detection --- circulating tumor cells (CTC) --- prostate cancer (PC3) --- cervical carcinoma (HeLa) --- label-free detection --- SERS --- Ag NPs --- coffee ring --- pesticide detection --- Surface-enhanced Raman spectroscopy (SERS) --- wire mesh --- steel mesh --- SERS platform --- Escherichia coli --- Bacillus subtilis --- biomolecule --- surface enhanced Raman spectroscopy (SERS) --- nanomaterial --- analysis --- identification --- biology --- chemometrics --- resistance --- biosensing --- rapid detection --- Ag nanowires --- tartrazine --- large yellow croaker --- surface-enhanced Raman spectroscopy --- transformer aging --- concentration detection --- circulating tumor cells (CTC) --- prostate cancer (PC3) --- cervical carcinoma (HeLa) --- label-free detection

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This book provides an overview of the design and physico-chemical properties of nanoparticles developed for biomedical applications such as targeting and detection of pathologies, nanovectorization of drugs, radiosensitization, metal detection, and nanocomposite implants. The considerations necessary when developing a new nanomedicine are also developed, including toxicological investigation, biodistribution, and efficacy. This book provides an accurate and current representation of the field by addressing the promises and hurdles of nanomedicine via 20 different pertinent studies. Covering a wide range of areas, this book is an excellent partner for physico-chemists, doctors, pharmacologists, and biochemists working on nanosciences dedicated to medicine, both in industry and in academia.

alginate --- chitosan --- gold nanoparticles --- biochemical mechanism --- cancer imaging --- lignin --- thioredoxin reductase --- antimiR --- nanoparticles --- surface enhanced Raman scattering --- biomedical applications --- protein --- multidrug resistant (MDR) microorganisms --- nano-bio interaction --- curcumin --- autophagy --- MIC --- nanoparticle --- biocompatible --- gene delivery --- self-assembly --- glioblastoma --- dual functional imaging nanoprobe --- SERS --- antibiotics --- biogenic nanoparticles --- Hg2+ ions detection --- antimicrobial --- histamine --- layer-by-layer --- dihydroartemisinin --- computational electromagnetism --- photolysis --- Ag-film --- chitosan nanoparticles --- UiO-66 --- plasma liquid Interactions --- anticancer --- MBC --- nanophotonics --- targeted nanoparticles --- near-infrared --- hybrid Fe-Si nanoparticles --- FTIR --- thermoplastic polymer --- synergism --- prognosis --- medical devices --- silver nanoparticles --- glioma --- plasma --- iron oxide superparamagnetic nanoparticles --- oxidative stress --- mycosynthesis --- membrane integrity --- drug delivery --- nanocomposites --- finite element method --- cell labeling --- in vivo application --- non-thermal plasma --- nanocellulose --- biocompatibility --- liposomes --- nanocarriers --- upconversion nanoparticles --- Candida glabrata --- nanomaterials --- middle ear prosthesis --- short-wave infrared --- cytoreduction surgery --- fibril --- nanostars --- fluorescent nanoparticle --- density functional theory calculations --- cross-link --- mitoxantrone --- heat --- SERS sensor --- Caco2 cells --- apoptosis --- surface-enhanced Raman spectroscopy (SERS) --- MFC --- magnetic nanoparticles --- antibiotic resistance --- laser pyrolysis --- cytotoxicity --- core-shell nanoparticles --- enzyme --- extracellular --- nanomaterial synthesis --- cancer cell targeting --- nanodiamond --- breast cancer --- metal-enhanced fluorescence (MEF) --- PEG --- radiation --- trans-resveratrol derivative --- radiosensitization --- cancer --- surface-enhanced Raman scattering (SERS) --- TEM